Leguia, MarianaVila-Sanjurjo, AntónChain, PatrickMaljkovic Berry, IrinaJarman, Richard G.Pollett, Simon2025-01-102025-01-102019-11-21Leguia M, Vila-Sanjurjo A, Chain PSG et al. Precision Medicine and Precision Public Health in the Era of Pathogen Next-Generation Sequencing. The Journal of Infectious Diseases 2020;221:S289–91.1537-6613http://hdl.handle.net/2183/40658This is a pre-copyedited, author-produced version of an article accepted for publication in The Journal of Infectious Diseases following peer review. The version of record is available online at https://doi.org/10.1093/infdis/jiz424[Abstract] This brief report serves as an introduction to a supplement of the Journal of Infectious Diseases entitled “Next-Generation Sequencing (NGS) Technologies to Advance Global Infectious Disease Research.” We briefly discuss the history of NGS technologies and describe how the techniques developed during the past 40 years have impacted our understanding of infectious diseases. Our focus is on the application of NGS in the context of pathogen genomics. Beyond obvious clinical and public health applications, we also discuss the challenges that still remain within this rapidly evolving field.engInfectious diseasesNext generation sequencingPathogen genomicsjournal articleopen access10.1093/infdis/jiz424