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Potentiometric characterisation of cyclodextrin inclusion complexes of local anaesthetics

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URI: http://hdl.handle.net/2183/14120

Publication date

2011-09

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Bibliographic citation

Isabel Brandariz & Emilia Iglesias (2011) Potentiometric characterisation of cyclodextrin inclusion complexes of local anaesthetics, Supramolecular Chemistry, 23:9, 607-613, DOI: 10.1080/10610278.2011.593632

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Academic degree

Abstract

The complexation of several local anaesthetics by β and γ-cyclodextrins was studied by potentiometry with glass electrode. Tetracaine and dibucaine complexation constants were determined at 25°C in the presence of 0.1 M of NaCl. It was found that prilocaine and lidocaine complexes cannot be detected.

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Keywords

Inclusion complexes Cyclodextrin Potentiometric technique Local anaesthetics

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http://dx.doi.org/10.1080/10610278.2011.593632

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This is an Accepted Manuscript of an article published by Taylor & Francis Group in Supramolecular Chemistry on Volume 23, Issue 9, September 2011, available online at: http://www.tandfonline.com/10.1080/10610278.2011.593632

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Investigación (FCIE)