Amino Acid–Viologen Hybrids: Synthesis, Cucurbituril Host–Guest Chemistry, and Implementation on the Production of Peptides
| UDC.coleccion | Investigación | es_ES |
| UDC.departamento | Química | es_ES |
| UDC.endPage | 764 | es_ES |
| UDC.grupoInv | Química Molecular e de Materiais (QUIMOLMAT) | es_ES |
| UDC.issue | 1 | es_ES |
| UDC.journalTitle | The Journal of Organic Chemistry | es_ES |
| UDC.startPage | 760 | es_ES |
| UDC.volume | 87 | es_ES |
| dc.contributor.author | Barravecchia Prado, Liliana Inés | |
| dc.contributor.author | Neira, Iago | |
| dc.contributor.author | Pazos, Elena | |
| dc.contributor.author | Peinador, Carlos | |
| dc.contributor.author | García, Marcos D. | |
| dc.date.accessioned | 2022-03-08T11:01:16Z | |
| dc.date.available | 2022-03-08T11:01:16Z | |
| dc.date.issued | 2021-12-10 | |
| dc.description | Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG | es_ES |
| dc.description.abstract | [Abstract] We present herein the development of a series of viologen–amino acid hybrids, obtained in good yields either by successive alkylations of 4,4′-bipyridine, or by Zincke reactions followed by a second alkylation step. The potential of the obtained amino acids has been exemplified, either as typical guests of the curcubituril family of hosts (particularly CB[7]/[8]) or as suitable building blocks for the solution/solid-phase synthesis of two model tripeptides with the viologen core inserted within their sequences. | es_ES |
| dc.description.sponsorship | The authors are grateful for the funding received from the Agencia Estatal de Investigación and FEDER (PID2019-105272GB-I00 and CTQ2017-89166-R), the Consellería de Educación, Universidade e Formación Profesional, Xunta de Galicia (ED431C 2018/39 and 508/2020), and the European Research Council (Grant Agreement No. 851179). I.N. thanks the MECD (FPU program) for financial support. E.P. thanks the Agencia Estatal de Investigación for her Ramón y Cajal contract (RYC2019-027199-I). Funding for open access charge: Universidade da Coruña/CISUG | es_ES |
| dc.description.sponsorship | Xunta de Galicia; ED431C 2018/39 | es_ES |
| dc.description.sponsorship | Xunta de Galicia; ED431C 508/2020 | es_ES |
| dc.identifier.citation | Barravecchia, L.; Neira, I.; Pazos, E.; Peinador, C.; García, M. D. Amino Acid–Viologen Hybrids: Synthesis, Cucurbituril Host–Guest Chemistry, and Implementation on the Production of Peptides. J. Org. Chem. 2022, 87, 1, 760–764. https://doi.org/10.1021/acs.joc.1c02040 | es_ES |
| dc.identifier.issn | 0022-3263 | |
| dc.identifier.issn | 1520-6904 | |
| dc.identifier.uri | http://hdl.handle.net/2183/29896 | |
| dc.language.iso | eng | es_ES |
| dc.publisher | American Chemical Society | es_ES |
| dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/851179 | es_ES |
| dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-105272GB-I00/ES/DESARROLLO DE NUEVOS CICLOFANOS AUTOENSAMBLADOS Y SU IMPLEMENTACION EN ESTRUCTURAS NANOMETRICAS/ | |
| dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/CTQ2017-89166-R/ES/HERRAMIENTAS PEPTIDICAS PARA APLICACIONES BIOLOGICAS: SENSORES INTELIGENTES PARA ESTUDIAR NITRACION DE PROTEINAS Y NANOMATERIALES CON FUNCIONALIDADES MODULABLES/ | |
| dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RYC2019-027199-I/ES/ | |
| dc.relation.uri | https://doi.org/10.1021/acs.joc.1c02040 | es_ES |
| dc.rights | Atribución 4.0 Internacional | es_ES |
| dc.rights.accessRights | open access | es_ES |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.title | Amino Acid–Viologen Hybrids: Synthesis, Cucurbituril Host–Guest Chemistry, and Implementation on the Production of Peptides | es_ES |
| dc.type | journal article | es_ES |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 2937ed3e-6088-4530-ba68-f72739264fd1 | |
| relation.isAuthorOfPublication | df653ec8-e85e-4f0c-9ffb-4b81d43fc20c | |
| relation.isAuthorOfPublication | 86a2d4e7-c65e-4cbb-ad78-02434b0eca6d | |
| relation.isAuthorOfPublication.latestForDiscovery | 2937ed3e-6088-4530-ba68-f72739264fd1 |
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