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http://hdl.handle.net/2183/14516 Cross nearest-spike interval based method to measure synchrony dynamics
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Faes, Christel
Molenberghs, Geert
Espinosa, Nelson
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Bibliographic citation
González Montoro AM, Cao R, Faes C, Molenberghs G, Espinosa N, Cudeiro J, Mariño J. Cross nearest-spike interval based method to measure synchrony dynamics. Math Biosci Eng. 2014;11(1):27-48
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Abstract
[Abstract] A new synchrony index for neural activity is de ned in this paper.
The method is able to measure synchrony dynamics in low ring rate scenarios.
It is based on the computation of the time intervals between nearest spikes of
two given spike trains. Generalized additive models are proposed for the synchrony
pro les obtained by this method. Two hypothesis tests are proposed
to assess for di erences in the level of synchronization in a real data example.
Bootstrap methods are used to calibrate the distribution of the tests. Also, the
expected synchrony due to chance is computed analytically and by simulation
to assess for actual synchronization.
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This is a pre-copy-editing, author-produced PDF of an article accepted for publication in "Mathematical Biosciences and Engineering" following peer review.