The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands [Review]

Maestro, Miguel; Seoane, Samuel

Use this link to cite:

http://hdl.handle.net/2183/32531

The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands [Review]

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Maestro_Miguel_2022_Centennial_Collection_VDR_Ligands_Metabolites_Analogs_Hybrids_NonSecosteroidal_Ligands.pdf (22.44 MB)

Identifiers

URI: http://hdl.handle.net/2183/32531

DOI: 10.3390/nu14224927

Publication date

2022-11-21

Authors

Maestro, Miguel

Seoane, Samuel

Bibliographic citation

Maestro, M.A.; Seoane, S. The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands. Nutrients 2022, 14, 4927. https://doi.org/10.3390/nu14224927

Abstract

[Abstract] Since the discovery of vitamin D a century ago, a great number of metabolites, analogs, hybrids and nonsteroidal VDR ligands have been developed. An enormous effort has been made to synthesize compounds which present beneficial properties while attaining lower calcium serum levels than calcitriol. This structural review covers VDR ligands published to date.

Description

This article belongs to the Special Issue A Commemorative Issue in Honor of Centennial of the Discovery of Vitamin D-The Central Role of Vitamin D in Physiology