Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways

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UDC.coleccionInvestigaciónes_ES
UDC.departamentoFisioterapia, Medicina e Ciencias Biomédicases_ES
UDC.endPage1057es_ES
UDC.grupoInvInvestigación en Xerontoloxía (INIBIC)es_ES
UDC.grupoInvGrupo de Investigación en Xerontoloxía e Xeriatría (GIGG)es_ES
UDC.institutoCentroINIBIC - Instituto de Investigacións Biomédicas de A Coruñaes_ES
UDC.issue12es_ES
UDC.journalTitleJournal of the American Medical Directors Associationes_ES
UDC.startPage1049es_ES
UDC.volume18es_ES
dc.contributor.authorMarcos-Pérez, Diego
dc.contributor.authorSánchez-Flores, María
dc.contributor.authorMaseda, Ana
dc.contributor.authorLorenzo-López, Laura
dc.contributor.authorMillán-Calenti, José Carlos
dc.contributor.authorStrasser, Barbara
dc.contributor.authorGostner, Johanna
dc.contributor.authorFuchs, Dietmar
dc.contributor.authorPásaro, Eduardo
dc.contributor.authorValdiglesias, Vanessa
dc.contributor.authorLaffon, Blanca
dc.date.accessioned2018-01-15T11:23:39Z
dc.date.embargoEndDate2018-08-08es_ES
dc.date.embargoLift2018-08-08
dc.date.issued2017-08-08
dc.descriptionOriginal studyes_ES
dc.description.sponsorshipThis work was supported by Xunta de Galicia (grant numbers ED431B 2016/013, GPC2014/082, and FrailNet network IN607C 2016/08). V. Valdiglesias was supported by a Xunta de Galicia postdoctoral fellowship (reference ED481B 2016/190-0). D. Marcos-Pérez and M. Sánchez-Flores were supported by INDITEX-UDC fellowships.es_ES
dc.description.sponsorshipXunta de Galicia; GPC2014/082es_ES
dc.description.sponsorshipXunta de Galicia; IN607C 2016/08es_ES
dc.description.sponsorshipXunta de Galicia; ED431B 2016/013
dc.identifier.citationMarcos-Pérez D, Sánchez-Flores M, Maseda A, Lorenzo-López L, Millán-Calenti JC, Strasser B, Gostner JM, Fuchs D, Pásaro E, Valdiglesias V, Laffon B. Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways. J Am Med Dir Assoc. 2017 Dec 1;18(12):1049-1057.es_ES
dc.identifier.issn1525-8610
dc.identifier.issn1538-9375
dc.identifier.urihttp://hdl.handle.net/2183/19988
dc.language.isospaes_ES
dc.publisherElsevier para AMDA (The Society for Post-Acute and Long-Term Cara Medicine)es_ES
dc.relation.urihttp://dx.doi.org/10.1016/j.jamda.2017.06.021es_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY 4.0)es_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectFrailtyes_ES
dc.subjectImmune activationes_ES
dc.subjectKynurenine/tryptophan ratio neopterines_ES
dc.subjectNitritees_ES
dc.subjectPhenylalanine/tyrosine ratioes_ES
dc.titleFrailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathwayses_ES
dc.typejournal articlees_ES
dspace.entity.typePublication
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