Use this link to cite:
http://hdl.handle.net/2183/18343 Paramagnetic lanthanide chelates for multicontrast MRI
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Authors
Cakic, Nevenka
Savic, Tanja
Stricker-Shaver, Janice
Truffault, Vincent
Mirkes, Christian
Pohmann, Rolf
Scheffler, Klaus
Angelovski, Goran
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Journal Title
Bibliographic citation
Cakic N., Savic T., Stricker-Shaver J., Truffault V., Platas-Iglesias C., Mirkes C., et al. Paramagnetic lanthanide chelates for multicontrast MRI. Chem. Commun. 2016, 59, 9224. https://doi.org/10.1039/C6CC04011J
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Abstract
[Abstract] The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex exhibits an extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.