Self-Assembled Peptide–Inorganic Nanoparticle Superstructures: From Component Design to Applications

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Pigliacelli, Claudia
Sánchez-Fernández, Rosalía

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C. Pigliacelli, R. Sánchez-Fernández, M. D. García, C. Peinador and E. Pazos, Self-assembled peptide–inorganic nanoparticle superstructures: from component design to applications, Chem. Commun., 2020, 56, 8000–8014. https://doi.org/10.1039/D0CC02914A

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[Abstract] Peptides have become excellent platforms for the design of peptide–nanoparticle hybrid superstructures, owing to their self-assembly and binding/recognition capabilities. Morover, peptide sequences can be encoded and modified to finely tune the structure of the hybrid systems and pursue functionalities that hold promise in an array of high-end applications. This feature article summarizes the different methodologies that have been developed to obtain self-assembled peptide–inorganic nanoparticle hybrid architectures, and discusses how the proper encoding of the peptide sequences can be used for tailoring the architecture and/or functionality of the final systems. We also describe the applications of these hybrid superstructures in different fields, with a brief look at future possibilities towards the development of new functional hybrid materials.

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