Relevance of the extraction stage on the anti-inflammatory action of fucoidans

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Flórez-Fernández, Noelia
Torres, María Dolores
Buján, Manuela
Muíños, Alexandra
Lamas Vázquez, María José
Domínguez, Herminia

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Flórez-Fernández N, Vaamonde-García C, Torres MD, Buján M, Muíños A, Muiños A, Lamas-Vázquez MJ, Meijide-Faílde R, Blanco FJ, Domínguez H. Relevance of the extraction stage on the anti-inflammatory action of fucoidans. Pharmaceutics. 2023 Mar 1;15(3):808

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[Abstract] The anti-inflammatory action of fucoidans is well known, based on both in vitro and some in vivo studies. The other biological properties of these compounds, their lack of toxicity, and the possibility of obtaining them from a widely distributed and renewable source, makes them attractive novel bioactives. However, fucoidans' heterogeneity and variability in composition, structure, and properties depending on seaweed species, biotic and abiotic factors and processing conditions, especially during extraction and purification stages, make it difficult for standardization. A review of the available technologies, including those based on intensification strategies, and their influence on fucoidan composition, structure, and anti-inflammatory potential of crude extracts and fractions is presented.

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Creative Commons Attribution 4.0 International Licence (CC-BY 4.0)
Creative Commons Attribution 4.0 International Licence (CC-BY 4.0)

Except where otherwise noted, this item's license is described as Creative Commons Attribution 4.0 International Licence (CC-BY 4.0)