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Rheumatoid arthritis response to treatment across IgG1 allotype – anti-TNF incompatibility: a case-only study
(BioMed Central, 2015-03-18)
[Abstract] INTRODUCTION:
We have hypothesized that incompatibility between the G1m genotype of the patient and the G1m1 and G1m17 allotypes carried by infliximab (INX) and adalimumab (ADM) could decrease the efficacy of ...
Evaluation of 12 GWAS-drawn SNPs as biomarkers of rheumatoid arthritis response to TNF inhibitors. A potential SNP association with response to etanercept
(PLoS, 2019-02-28)
[Abstract] Research in rheumatoid arthritis (RA) is increasingly focused on the discovery of biomarkers that could enable personalized treatments. The genetic biomarkers associated with the response to TNF inhibitors (TNFi) ...
Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus
(BioMed Central, 2014-06-19)
[Abstract] INTRODUCTION:
We aimed to replicate a recent study which showed higher genetic risk load at 15 loci in men than in women with systemic lupus erythematosus (SLE). This difference was very significant, and it was ...