Listar1. Investigación por tema "NMR imaging"

Mostrando ítems 1-7 de 7

    • Approaching the kinetic inertness of macrocyclic gadolinium(III)-based MRI contrast agents with highly rigid open-chain derivatives 

      Tircsó, Gyula; Regueiro-Figueroa, Martín; Nagy, Viktória; Garda, Zoltán; Garai, Tamás; Kálmán, Ferenc; Esteban-Gómez, David; Tóth, Éva; Platas-Iglesias, Carlos (Wiley, 2016-01-08)
      [Abstract] A highly rigid open-chain octadentate ligand (H4cddadpa) containing a diaminocylohexane unit to replace the ethylenediamine bridge of 6,6′-[(ethane-1,2 diylbis{(carboxymethyl)azanediyl})bis(methylene)] dipicolinic ...

    • Gd3+-based magnetic resonance imaging contrast agent responsive to Zn2+ 

      Regueiro-Figueroa, Martín; Gündüz, Serhat; Patinec, Véronique; Logothetis, Nikos K.; Esteban-Gómez, David; Tripier, Raphaël; Angelovski, Goran; Platas-Iglesias, Carlos (American Chemical Society, 2015-10-15)
      [Abstract] We report the heteroditopic ligand H5L, which contains a DO3A unit for Gd3+ complexation connected to an NO2A moiety through a N-propylacetamide linker. The synthesis of the ligand followed a convergent route ...

    • High relaxivity Mn2+-based MRI contrast agents 

      Regueiro-Figueroa, Martín; Rolla, Gabriele A.; Esteban-Gómez, David; Blas, Andrés de; Rodríguez-Blas, Teresa; Botta, Mauro; Platas-Iglesias, Carlos (Wiley, 2014-12-16)
      [Abstract] Stable Mn2+ mono- and binuclear complexes containing pentadentate 6,6′-((methylazanediyl)bis(methylene)) dipicolinic acid coordinating units give remarkably high relaxivities due to the presence of two inner-sphere ...

    • Magnetic anisotropies in rhombic lanthanide(III) complexes do not conform to Bleaney’s theory 

      Castro, Goretti; Regueiro-Figueroa, Martín; Esteban-Gómez, David; Pérez-Lourido, Paulo; Platas-Iglesias, Carlos; Valencia, Laura (American Chemical Society, 2016-04-04)
      [Abstract] We report a complete set of magnetic susceptibilities of lanthanide complexes with a macrocyclic ligand based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing four hydroxyethyl ...

    • Paramagnetic lanthanide chelates for multicontrast MRI 

      Cakic, Nevenka; Savic, Tanja; Stricker-Shaver, Janice; Truffault, Vincent; Platas-Iglesias, Carlos; Mirkes, Christian; Pohmann, Rolf; Scheffler, Klaus; Angelovski, Goran (Royal Society of Chemistry, 2016-06-02)
      [Abstract] The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex ...

    • Transient versus static electron spin relaxation in Mn2+ complexes relevant as MRI contrast agents 

      Platas-Iglesias, Carlos; Esteban-Gómez, David; Helm, Lothar; Regueiro-Figueroa, Martín (American Chemical Society, 2016-08-18)
      [Abstract] The zero-field splitting (ZFS) parameters of the [Mn(EDTA)(H2O)]2–·2H2O and [Mn(MeNO2A)(H2O)]·2H2O systems were estimated by using DFT and ab initio CASSCF/NEVPT2 calculations (EDTA = 2,2′,2″,2‴-(ethane-1,2-di ...

    • Unexpected Changes in the Population of Coordination Isomers for the Lanthanide Ion Complexes of DOTMA–Tetraglycinate 

      Kumas, Cemile; Fernando, W. Shirangi; Zhao, Piyu; Regueiro-Figueroa, Martín; Kiefer, Garry E.; Martins, André F.; Platas-Iglesias, Carlos; Sherry, A. Dean (American Chemical Society, 2016-09-19)
      [Abstract] Lanthanide complexes with DOTA–tetraglycinate (DOTA-(gly)4) heavily favor the square antiprismatic (SAP) coordination isomer in aqueous solution, a structural feature that has made them useful as water-based ...