Now showing items 1-2 of 2

    • Gender-Affirming Hormone Therapy Modifies the CpG Methylation Pattern of the ESR1 Gene Promoter After Six Months of Treatment in Transmen 

      Fernández, Rosa; Ramírez, Karla; Gómez-Gil, Esther; Cortés-Cortés, Joselyn; Mora, Mireia; Aranda, Gloria; Delgado Zayas, Enrique; Esteva, Isabel; Almaraz, Mari Cruz; Guillamon, Antonio; Pásaro, Eduardo (2020)
      [Abstract] Background Brain sexual differentiation is a process that results from the effects of sex steroids on the developing brain. Evidence shows that epigenetics plays a main role in the formation of enduring brain ...
    • Mitochondrial genetics and epigenetics in osteoarthritis 

      Rego-Pérez, Ignacio; Durán-Sotuela, Alejandro; Ramos-Louro, Paula; Blanco García, Francisco J (Frontiers, 2020-01-17)
      [Abstract] During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated. Not only mitochondrial dysfunction but also mitochondrial ...