Now showing items 1277-1286 of 1286

    • Weight-related quality of life in spanish obese subjects suitable for bariatric surgery is lower than in their North American counterparts: a case–control study 

      Caixás, Assumpta; Lecube, Albert; Morales, María-José; Calañas Continente, Alfonso; Moreiro, José; Cordido, Fernando; Díaz, María-Jesús; Másmiquel, Lluís; Moreno, Basilio; Vidal, Josep; Goday, Albert; Arrizabalaga, Juan-José; García-Luna, Pedro-Pablo; Iglesias, Paloma; Burguera, Bartolomé; Rubio, Miguel-Ángel; Monereo, Susana; Crosby, Ross D.; Kolotkin, Ronette L. (Springer, 2012-10-23)
      [Abstract] Background: Obesity impairs quality of life, but the perception of the impairment could be different from one country to another. The purpose was to compare weight-related quality of life (QOL) between cohorts ...
    • What causes grief in dementia caregivers? 

      Warchol-Biedermann, Katarzyna; Mojs, Ewa; Gregersen, Rikke; Maibom, Kirsten; Millán-Calenti, José Carlos; Maseda, Ana (Elsevier, 2014-06-26)
      [Abstract] Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the world. Most AD patients become dependent on their relatives, i.e. family caregivers. Providing care to a person with AD ...
    • What did we learn from 'omics' studies in osteoarthritis 

      Ruiz-Romero, Cristina; Rego-Pérez, Ignacio; Blanco García, Francisco J (Wolters Kluwer, 2018-01-01)
      [Abstract] Purpose of review: 'Omics' technologies developed for the massive analysis of the major biologically relevant molecules (genes, proteins, metabolites) have been applied to the study of osteoarthritis (OA) for ...
    • Will neurological care change over the next 5 years due to the COVID-19 pandemic?: key informant consensus survey 

      Matías-Guiu, J.; Matías-Guiu, Jordi A.; Álvarez-Sabín, José; Ara, José Ramón; Arenillas, Juan; Casado-Naranjo, Ignacio; Castellanos, María del Mar; Jiménez-Hernández, María Dolores; Lainez-Andrés, José Miguel; Moral, Esther; Morales, Ana; Rodríguez-Antigüedad, Alfredo; Segura, Tomás; Serrano-Castro, Pedro; Díez-Tejedor, Exuperio (Elsevier, 2020-05-21)
      [Abstract] Introduction. The COVID-19 pandemic will give rise to long-term changes in neurological care, which are not easily predictable. Material and methods. A key informant survey was used to enquire about the changes ...
    • Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast‐derived ADAMTS‐7 and ‐12 

      Pérez-García, Selene; Carrión, Mar; Villanueva-Romero, Raúl; Hermida Gómez, Tamara; Fernández-Moreno, Mercedes; Mellado, Mario; Blanco García, Francisco J; Juarranz, Yasmina; Gomariz, Rosa P. (Wiley, 2019-03-22)
      [Abstract] Failure of therapeutic approaches for the treatment of osteoarthritis (OA) based on the inhibition of metalloproteinases, might be because of their constitutive expression in homeostasis, together with their ...
    • Wnt signalling and cancer stem cells 

      Espada, Jesús; Calvo, Moisés B.; Díaz-Prado, Silvia; Medina, Vanessa (Springer, 2009-07-15)
      [Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and ...
    • World Alzheimer's month: cognitive frailty, Alzheimer's disease and dementia: how do they relate?: the role of cognitive reserve 

      Lorenzo-López, Laura; Gandoy-Crego, Manuel; Tolentino, Leida C. (Frontiers, 2023-10-06)
    • Worse outcome in stroke patients treated with rt-PA without early reperfusion: associated factors 

      Iglesias-Rey, Ramón; Rodríguez-Yáñez, Manuel; Rodríguez-Castro, Enrique; Pumar, José Manuel; Arias, Susana; Santamaría, María; López-Dequidt, Iria; Hervella, Pablo; Correa-Paz, Clara; Sobrino, Tomás; Vivien, Denis; Campos, Francisco; Castellanos, María del Mar; Castillo, José (Springer Nature, 2017-11-07)
      [Abstract] Based on preclinical studies suggesting that recombinant tissue plasminogen activator (rt-PA) may promote ischemic brain injuries, we investigated in patients the possible risk of worse clinical outcome after ...
    • Yo soy vosotros 

      Mariño Alfonso, Xurxo (Universitat de València, 2019)
      [Resumen] A los humanos modernos nos está resultando complicado encontrarnos. El mayor reto de la neurociencia está en comprender cómo surge la mente autoconsciente a partir de la actividad electroquímica de la ...
    • ZenoSWATH DIA proteomics and clustering analysis of the effect of cysteamine at the cellular level in cystinotic fibroblasts 

      Ortea, Ignacio; Rodríguez-Martínez, Lorena; Carrera, Mónica; Fafián Labora, Juan Antonio; Arufe, M.C.; González-Barcia, Miguel; Fernández-Ferreiro, Anxo; Mateos, Jesús (Elsevier, 2024-11-05)
      [Abstract] Cysteamine, an aminothiol, is the only available treatment for cystinosis, an incurable metabolic recessive disease characterized by detrimental symptoms at the renal, ocular, and muscular levels. Cystinosis is ...