Browsing Investigación (FCS) by Title

Now showing items 821-840 of 1289

    • Naming as a window to word retrieval changes in healthy and pathological ageing: Methodological considerations 

      Martínez-Ferreiro, Silvia (Wiley, 2022-12-12)
      [Abstract] Background: Word retrieval skills change across the lifespan. Permanent alterations in the form of decreased accuracy or increased response time can be a consequence of both normal ageing processes or the presence ...

    • Nasal intermittent positive pressure ventilation and bronchopulmonary dysplasia among very preterm infants never intubated during the first neonatal admission: a multicenter cohort study 

      Ávila-Álvarez, Alejandro; García-Muñoz Rodrigo, Fermín; Solís-García, Gonzalo; Pértega-Díaz, Sonia; Sánchez Luna, Manuel; Iriondo-Sanz, Martín; Elorza Fernández, Dolores; Zozaya, Carlos (Frontiers, 2022-04-27)
      [Abstract] Introduction: While non-invasive positive-pressure ventilation (NIPPV) is increasingly used as a mode of respiratory support for preterm infants, it remains unclear whether this technique translates into improved ...

    • Natural history and surgical outcomes of Rathke’s cleft cysts: a spanish multicenter study 

      Menéndez-Torre, Edelmiro Luis; Gutiérrez-Hurtado, Alba; Ollero García-Agulló, María Dolores; Irigaray Echarri, Ana; Martín, Patricia; Parra, Paola; González-Molero, Inmaculada; Araújo-Castro, Marta; Idrobo, Cindy; Moure Rodríguez, María Dolores; Molina, Ana Rosa; Biagetti, Betina; Iglesias, Pedro; Paja, Miguel; Villar-Taibo, Rocío; Pena-Dubra, Alberto; Vicente Delgado, Almudena; Guerrero-Pérez, Fernando; Cordido, Fernando; Aulinas, Anna; Mateu, Manel; Soto-González, Alfonso (Frontiers, 2024-06-17)
      [Abstract] Rathke’s cleft cysts (RCC) are a common type of lesion found in the sellar or suprasellar area. They are usually monitored clinically, but in some cases, surgery may be required. However, their natural progression ...

    • Neoplasias en pacientes con infección por VIH: estudio descriptivo de 129 casos en el período 1993-2010 

      Meijide, Héctor; Mena, Álvaro; Pernas, Berta; Castro-Iglesias, Ángeles; López, Soledad; Vázquez-Rodríguez, Pilar; Bello, Laura; Baliñas, Josefa; Rodríguez-Martínez, Guillermo; Pedreira, José D. (Sociedad Chilena de Infectología, 2013)
      [Resumen] Introducción: Uno de los problemas asociados a la infección por VIH es el desarrollo de neoplasias. La incidencia y espectro de los distintos cánceres se ha visto modificada con la incorporación del tratamiento ...

    • Neurological recovery after traumatic spinal cord injury: prognostic value of magnetic resonance 

      Mora-Boga, Rubén; Vázquez-Muíños, Olalla; Pértega-Díaz, Sonia; Salvador de la Barrera, Sebastián; Ferreiro-Velasco, M.E.; Rodríguez-Sotillo, Antonio; Meijide-Faílde, Rosa; Montoto Marqués, Antonio (Nature, 2022-02-01)
      [Abstract] Study design: Retrospective observational study. Objectives: Assess the relationship between Magnetic Resonance (MR) image patterns and neurological recovery in patients with Traumatic Spinal Cord Injury ...

    • Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping 

      van Helvoort, Eefje M.; Welsing, Paco M.J.; Jansen, Mylène P.; Gielis, Willem Paul; Loef, Marieke; Kloppenburg, Margreet; Blanco García, Francisco J; Haugen, Ida K.; Berenbaum, Francis; Bay-Jensen, Anne-C; Ladel, Christoph H.; Lalande, Agnes; Larkin, Jonathan; Loughlin, John; Mobasheri, Ali; Weinans, Harrie; Lafeber, Floris; Eijkelkamp, Niels; Mastbergen, Simon (BMJ, 2021-12-15)
      [Abstract] Objectives: Osteoarthritis (OA) patients with a neuropathic pain (NP) component may represent a specific phenotype. This study compares joint damage, pain and functional disability between knee OA patients with ...

    • New insights into molecular mechanisms of sunitinib-associated side effects 

      Aparicio Gallego, Guadalupe; Blanco, Moisés; Figueroa, Angélica; García-Campelo, Rosario; Valladares-Ayerbes, Manuel; Grande Pulido, Enrique; Antón-Aparicio, Luis M. (American Association for Cancer Research, 2011-12)
      [Abstract] The introduction of targeted therapy represents a major advance in the treatment of tumor progression. Targeted agents are a novel therapeutic approach developed to disrupt different cellular signaling pathways. ...

    • New tools for old problems: magnetic stimulation to study (and help) the brain 

      Rivadulla, Casto; Aguilá Macías, Jordi; Prieto-Soler, Sandra; Aguilar, Juan; Cudeiro, Javier (Springer Nature, 2017)
      [Abstract] Magnetic stimulation techniques, either repetitive TMS (rTMS) or Static Magnetic Fields, allow to modulate brain activity through the skull in a non invasive and painless way. When rTMS is used, low frequencies ...

    • Next-generation sequencing and quantitative proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging 

      Mateos, Jesús; Fafián Labora, Juan Antonio; Morente-López, Miriam; Lesende-Rodríguez, Iván; Monserrat, Lorenzo; Ódena, María A.; Oliveira, Eliandre de; De-Toro, Javier; Arufe, M.C. (PLOS, 2018-10-31)
      [Abstract] Hutchinson-Gilford progeria syndrome (HGPS) is a very rare fatal disease characterized for accelerated aging. Although the causal agent, a point mutation in LMNA gene, was identified more than a decade ago, the ...

    • NF-κB/IKK Activation by Small Extracellular Vesicles Within the SASP 

      Fafián Labora, Juan Antonio; O'Loghlen, Ana (Wiley, 2021-06-29)
      [Abstract] Cellular senescence plays an important role in different biological and pathological conditions. Senescent cells communicate with their microenvironment through a plethora of soluble factors, metalloproteases ...

    • Niosomes-Based Gene Delivery Systems for Effective Transfection of Human Mesenchymal Stem Cells 

      Carballo-Pedrares, Natalia; Kattar, Axel; Concheiro, Ángel; Álvarez-Lorenzo, Carmen; Rey-Rico, Ana (Elsevier, 2021-07-11)
      [Abstract] Gene transfer to mesenchymal stem cells (MSCs) has arisen as a powerful approach to increase the therapeutic potential of this effective cell population. Over recent years, niosomes have emerged as self-assembled ...

    • Nitric Oxide Compounds Have Different Effects Profiles on Human Articular Chondrocyte Metabolism 

      Andrés, María C. de; Maneiro, Emilia; Martín, Miguel A.; Arenas, Joaquín; Blanco García, Francisco J (BioMed Central, 2013-09-11)
      [Abstract] Introduction. The pathogenesis of osteoarthritis (OA) is characterized by the production of high amounts of nitric oxide (NO), as a consequence of up-regulation of chondrocyte-inducible nitric oxide synthase ...

    • Nitric oxide-mediated cortical activation: a diffuse wake-up system 

      Mariño Alfonso, Xurxo; Cudeiro, Javier (Society of Neuroscience, 2003)
      Nitric oxide (NO) has been implicated in some of the central pathways engaged in the regulation of the sleep–wake cycle. The existence of nitric oxide synthase (NOS) in the cholinergic basal forebrain (BF) cells projecting ...

    • No obesity paradox for health-related quality of life in patients with heart failure and reduced ejection fraction: insights from the VIDA multicenter study 

      Cassadó-Valls, Paula; Enjuanes, Cristina; Anguita, Manuel; Formiga, Francesc; Almenar, Luis; Crespo-Leiro, María Generosa; Manzano, Luis; Muñiz, Javier; Chaves, José; Hidalgo, Encarna; Ramos-Polo, Raúl; Yun, Sergi; José-Bazán, Núria; Moliner, Pedro; Comín-Colet, Josep (MDPI, 2024-12-12)
      [Abstract] Background and Objectives: Previous studies showed that, paradoxically, obese patients with heart failure (HF) have better clinical outcomes compared to overweight, normal, or underweight patients. Scientific ...

    • Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015) 

      Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; García-Sancho, Paula; Díez, Juan José; Cordido, Fernando; Villabona, Carles (Elsevier, 2017-04-04)
      [Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design ...

    • Notch signalling in cancer stem cells 

      Bolós Fernández, Victoria; Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Díaz-Prado, Silvia; Grande Pulido, Enrique (Springer, 2009)
      [Abstract] A new theory about the development of solid tumours is emerging from the idea that solid tumours, like normal adult tissues, contain stem cells (called cancer stem cells) and arise from them. Genetic mutations ...

    • Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma 

      Puente, Javier; Lainez, Nuria; Dueñas, Marta; Méndez-Vidal, María José; Esteban, Emilio; Castellano, Daniel; Martínez-Fernández, Mónica; Basterretxea, Laura; Juan-Fita, María José; Antón-Aparicio, Luis M.; León, Luis; Lambea, Julio; Pérez-Valderrama, Begoña; Vázquez, Sergio; Suárez, Cristina; García del Muro, Xavier; Gallardo, Enrique; Maroto, José Pablo; Samaniego, M. Luz; Suárez-Paniagua, Beatriz; Sanz, Julián; Paramio, Jesús M. (Impact Journals, 2017-03-23)
      [Abstract] Background: Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further ...

    • Un nuevo enfoque terapéutico, termalismo y el trastorno del espectro autista 

      Meijide-Faílde, Rosa (Autismo Galicia, 2024-10-21)
      [Resumen] Los tratamientos en balnearios utilizan aguas mineromedicinales con el objetivo de mejorar y prevenir problemas de salud. Con una gran tradición médica de uso en los últimos años se han realizado múltiples ...

    • Nutritional determinants of frailty in older adults: a systematic review 

      Lorenzo-López, Laura; Maseda, Ana; Labra, Carmen de; Regueiro-Folgueira, Laura; Rodríguez-Villamil, José Luis; Millán-Calenti, José Carlos (BioMed Central, 2017-05-15)
      [Abstract] Background. Frailty is a geriatric syndrome that affects multiple domains of human functioning. A variety of problems contributes to the development of this syndrome; poor nutritional status is an important ...

    • O paradoxo dos videoxogos 

      Mariño Alfonso, Xurxo (Nova Escola galega, 2017)