Browsing Investigación (FCS) by Title

Now showing items 569-588 of 1286

    • Hakai reduces cell-substratum adhesion and increases epithelial cell invasion 

      Rodríguez-Rigueiro, Teresa; Valladares-Ayerbes, Manuel; Haz, Mar; Antón-Aparicio, Luis M.; Figueroa, Angélica (BioMed Central, 2011-11-03)
      [Abstract] Background. The dynamic regulation of cell-cell adhesions is crucial for developmental processes, including tissue formation, differentiation and motility. Adherens junctions are important components of the ...

    • Hand motor fatigability induced by a simple isometric task in spinal cord injury 

      Onate-Figuérez, Ana; Soto-León, Vanesa; Avendaño-Coy, Alejandro; Mordillo-Mateos, Laura; Pérez-Borrego, Yolanda A.; Redondo-Galán, Carolina; Arias, Pablo; Oliviero, Antonio (MDPI, 2022-08-30)
      [Abstract] This study aimed: (1) to evaluate the hand motor fatigability in people with spinal cord injury (SCI) and compare it with measurements obtained form an able-bodied population; (2) to compare the hand motor ...

    • Health determinants of nutritional status in community-dwelling older population: the VERISAÚDE study 

      Maseda, Ana; Gómez Caamaño, Sarai; Lorenzo-López, Laura; López-López, Rocío; Diego-Díez, Clara; Sanluís-Martínez, Verónica; Valdiglesias, Vanessa; Millán-Calenti, José Carlos (Cambridge, 2016-03-15)
      [Abstract] Objective Malnutrition is a common and relevant syndrome in elderly people due to its influence on quality of life. The main aim of the present study was to identify health determinants of malnutrition or risk ...

    • Healthcare experience among patients with type 2 diabetes: A cross-sectional survey using the IEXPAC tool 

      Orozco-Beltrán, Domingo; Artola-Menéndez, Sara; Hormigo-Pozo, Antonio; Cararach-Salami, Daniel; Alonso-Jerez, José Luis; Álvaro-Grande, Epifanio; Villalibre-Arias, Covadonga; De-Toro, Javier; Galindo-Puerto, María José; Marín-Jiménez, Ignacio; Gómez-García, Antón; Ledesma-Rodríguez, Rocío; Fernández, Gonzalo; Ferreira de Campos, Karine (Wiley, 2021-02-15)
      [Abstract] Aim: To assess the experience with health care among patients with type 2 diabetes (T2DM) and to evaluate patients' demographic variables and healthcare-related characteristics which may affect their ...

    • Healthcare experience and their relationship with demographic, disease and healthcare-related variables: a cross-sectional survey of patients with chronic diseases using the IEXPAC scale. 

      Orozco-Beltrán, Domingo; De-Toro, Javier; Galindo, María J.; Marín-Jiménez, Ignacio; Casellas, Francesc; Fuster-RuizdeApodaca, María J.; García-Vivar, María L.; Hormigo-Pozo, Antonio; Guilabert, Mercedes; Sánchez-Vega, Nuria; Fernández, Gonzalo; Cea-Calvo, Luis (Springer, 2018-11-15)
      [Abstract] BACKGROUND: Patient experience is acknowledged as a principal aspect of quality healthcare delivery, and it has implications with regard to outcomes. OBJECTIVES: Our objective was to evaluate the healthcare ...

    • Health‐related quality of life, social support, and caregiver burden between six and 120 months after heart transplantation: a Spanish multicenter cross‐sectional study 

      Delgado Jiménez, Juan Francisco; Almenar-Bonet, Luis; González-Vílchez, Francisco; Arizón-del-Prado, José M.; Gómez-Bueno, Manuel; De la Fuente-Galán, Luis; Brossa-Loidi, Vicens; Fernández-Yáñez, Juan; Díaz Molina, Beatriz; Pascual Figal, Domingo A.; Lage-Gallé, Ernesto; Sanz-Julve, Marisa; Manito-Lorite, Nicolás; Crespo-Leiro, María Generosa (Wiley, 2015-06-15)
      [Abstract] A multicenter cross-sectional study was conducted to determine the current heart transplant (HTx) outcomes in Spain. Clinical and functional status, health-related quality of life (HRQoL), social support, and ...

    • Heart Failure Association of the European Society of Cardiology position paper on the management of left ventricular assist device-supported patients for the non-left ventricular assist device specialist healthcare provider: Part 2: at the emergency department 

      Milicic, Davor; Ben-Avraham, Binyamin; Chioncel, Ovidiu; Barac, Yaron; Goncalvesova, Eva; Grupper, Avishai; Altenberger, Johann; Frigeiro, Maria; Ristic, Arsen; De Jonge, Nicolaas; Tsui, Steven; Lavee, Jacob; Rosano, Giuseppe; Crespo-Leiro, María Generosa; Coats, Andrew J.S.; Seferovic, Petar; Ruschitzka, Frank; Metra, Marco; Anker, Stefan; Filippatos, Gerasimos; Adamopoulos, Stamatis; Abuhazira, Miriam; Elliston, Jeremy; Gotsman, Israel; Hamdan, Righab; Hammer, Yoav; Hasin, Tal; Hill, Lorrena; Ben-Zadok, Osnat Itzhaki; Mullens, Wilfried; Nalbantgil, Sanem; Piepoli, Massimo; Ponikowski, Piotr; Potena, Luciano; Ruhparwar, Arjang; Shaul, Aviv; Tops, Laurens F.; Winnik, Stephan; Jaarsma, Tiny; Gustafsson, Finn; Ben-Gal, Tuvia (Wiley, 2021-09-14)
      [Abstract] The improvement in left ventricular assist device (LVAD) technology and scarcity of donor hearts have increased dramatically the population of the LVAD-supported patients and the probability of those patients ...

    • Heart rate control and its predictors in patients with heart failure and sinus rhythm: data from the European Society of Cardiology Long-Term Registry 

      Tyminska, Agata; Ozieranski, Krzysztof; Wawrzacz, Marek; Balsam, Pawel; Maciejewski, Cezary; Kleszczewska, Magdalena; Zawadzka, Magdalena; Marchel, Michal; Crespo-Leiro, María Generosa; Maggioni, Aldo P.; Drozdz, Jaroslaw; Opolski, Grzegorz; Grabowski, Marcin; Kaplon-Cieslicka, Agnieszka (Via Medica, 2022-08-17)
      [Abstract] Background: Higher resting heart rate (HR) in patients with heart failure (HF) and sinus rhythm (SR) is associated with increased mortality. In patients hospitalized for HF, the aim herein, was to assess the ...

    • Heart transplantation and left ventricular assist systems: not too early, not too late 

      Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo (Wiley, 2017-11-16)

    • Heart transplantation: focus on donor recovery strategies, left ventricular assist devices, and novel therapies 

      Crespo-Leiro, María Generosa; Costanzo, María Rosa; Gustafsson, Finn; Khush, Kiran K.; Macdonald, Peter S.; Potena, Luciano; Stehlik, Josef; Zuckermann, Andreas; Mehra, Mandeep R. (Oxford Academic, 2022-06-14)
      [Abstract] Heart transplantation is advocated in selected patients with advanced heart failure in the absence of contraindications. Principal challenges in heart transplantation centre around an insufficient and underutilized ...

    • Hedgehog signalling as a target in cancer stem cells 

      Medina Villaamil, Vanessa; Blanco, Moisés; Díaz-Prado, Silvia; Espada, Jesús (Spirnger, 2009)
      [Abstract] Hedgehog (Hh) is one of the most important signalling pathways. Together with the Wnt, TGF-β/BMP and Notch pathways, it is involved in both embryonic development and adult tissue homeostasis. This is because Hh ...

    • Helping the family carers of Alzheimer's patients: from theory... to practice: a preliminary study 

      Millán-Calenti, José Carlos; Gandoy-Crego, Manuel; Antelo-Martelo, M.; López-Martínez, M.; Riveiro López, M.P.; Mayán Santos, José Manuel (Elsevier, 2000-04-24)
      [Abstract] Alzheimer's disease (AD) represents one of the most important health issues in the western world. The ongoing care that the AD patient requires typically causes high stress levels, fatigue, irritation and ...

    • Hemophagocytic syndrome in patients from SLE Registry from the Spanish Society of Rheumatology (RELESSER) 

      Lois Iglesias, Ana J.; Rua Figueroa, I.; De-Toro, Javier; Zea-Mendoza, A.; López-Longo, J.; Calvo, J.; Galindo, M.; Uriarte-Isacelaya, E.; Pego-Reigosa, J. (BMJ, 2017)

    • Hemorragia digestiva alta secundaria a sarcoma de Kaposi gástrico y duodenal 

      Bello, Laura; Pardeiro Pértega, Remedios; Couto Wörner, Ignacio; Vázquez Rodríguez, Pilar; López-Calvo, Soledad; Castro-Iglesias, Ángeles; Mena, Álvaro; Alonso Aguirre, Pedro; Pedreira, José D. (Sociedad Española de Patología Digestiva, 2012)

    • Hepatitis E 3ra genotype infection in people living with HIV in Spain 

      Rivero-Juárez, A.; Frías, Mario; López-López, Pedro; Berenguer, Juan; García, Federico; Macías, Juan; Alcaraz, Begoña; Castro-Iglesias, Ángeles; Caballero-Gómez, Javier; Rivero, Antonio (Frontiers, 2020-09-11)
      [Abstract] Background: The objective of our study was to assess the prevalence and incidence of HEV in people living with HIV (PLWH) in a Spanish national cohort. Methods: Retrospective longitudinal study including PLWH ...

    • HFA of the ESC position paper on the management of LVAD supported patients for the non LVAD specialist healthcare provider part 1: introduction and at the non-hospital settings in the community 

      Ben-Avraham, Binyamin; Crespo-Leiro, María Generosa; Filippatos, Gerasimos; Gotsman, Israel; Seferovic, Petar; Hasin, Tal; Potena, Luciano; Milicic, Davor; Coats, Andrew J.S.; Rosano, Giuseppe; Ruschitzka, Frank; Metra, Marco; Anker, Stefan; Altenberger, Johann; Adamopoulos, Stamatis; Barac, Yaron; Chioncel, Ovidiu; De Jonge, Nicolaas; Elliston, Jeremy; Frigeiro, Maria; Goncalvesova, Eva; Grupper, Avishai; Hamdan, Righab; Hammer, Yoav; Hill, Lorrena; Ben-Zadok, Osnat Itzhaki; Abuhazira, Miriam; Lavee, Jacob; Mullens, Wilfried; Nalbantgil, Sanem; Piepoli, Massimo; Ponikowski, Piotr; Ristic, Arsen; Ruhparwar, Arjang; Shaul, Aviv; Tops, Laurens F.; Tsui, Steven; Winnik, Stephan; Jaarsma, Tiny; Gustafsson, Finn; Ben-Gal, Tuvia (Wiley, 2021-09-14)
      [Abstract] The accepted use of left ventricular assist device (LVAD) technology as a good alternative for the treatment of patients with advanced heart failure together with the improved survival of the LVAD-supported ...

    • HFA of the ESC position paper on the management of LVAD-supported patients for the non-LVAD specialist healthcare provider Part 3: at the hospital and discharge 

      Gustafsson, Finn; Chioncel, Ovidiu; Hasin, Tal; Grupper, Avishai; Shaul, Aviv; Nalbantgil, Sanem; Hammer, Yoav; Mullens, Wilfried; Tops, Laurens F.; Elliston, Jeremy; Tsui, Steven; Milicic, Davor; Altenberger, Johann; Abuhazira, Miriam; Winnik, Stephan; Lavee, Jacob; Piepoli, Massimo; Hill, Lorrena; Hamdan, Righab; Ruhparwar, Arjang; Anker, Stephan; Crespo-Leiro, María Generosa; Coats, Andrew J.S.; Filippatos, Gerasimos; Metra, Marco; Rosano, Giuseppe; Seferovic, Petar; Ruschitzka, Frank; Adamopoulos, Stamatis; Barac, Yaron; De Jonge, Nicolaas; Frigeiro, Maria; Goncalvesova, Eva; Gotsman, Israel; Ponikowski, Piotr; Potena, Luciano; Ristic, Arsen; Jaarsma, Tiny; Gal, Tuvia Ben; Ben-Avraham, Binyamin; Ben-Zadok, Osnat Itzhaki (Wiley, 2021-09-28)
      [Abstract] The growing population of left ventricular assist device (LVAD)-supported patients increases the probability of an LVAD- supported patient hospitalized in the internal or surgical wards with certain expected ...

    • Hif-1α knockdown reduces glycolytic metabolism and induces cell death of human synovial fibroblasts under normoxic conditions 

      Del Rey, Manuel J.; Valín, Álvaro; Usategui, Alicia; García-Herrero, Carmen M.; Sánchez-Aragó, María; Cuezva, José M.; Galindo, María; Bravo, Beatriz; Cañete, Juan D.; Blanco García, Francisco J; Criado, Gabriel; Pablos, José L. (Nature, 2017-06-16)
      [Abstract] Increased glycolysis and HIF-1α activity are characteristics of cells under hypoxic or inflammatory conditions. Besides, in normal O2 environments, elevated rates of glycolysis support critical cellular mechanisms ...

    • High efficacy and tolerability of hepatitis C genotype 2 treatment with direct-acting antivirals in real world: analysis of the Hepa-C Registry 

      Aranda, E.B.; Mariño, Zoe; Calvo, S.; Carrión, J.A.; Fernández, I.; García-Samaniego, J.; Baliellas, C.; Pascasio, J.M.; Albillos, A.; Carrillo, C.F.; Castro-Iglesias, Ángeles; Planas, J.M.M.; Giner, C.P.; Palomares, J.J.M.; Llaneras, J.; Arenas, J.; Fernández-Bermejo, M.; Fernández, C.; López, R.M.G.; García, P.B.; Romero-Gómez, Manuel; Sáez-Royuela, F. (Elsevier, 2017)

    • High efficacy of Sofosbuvir plus Simeprevir in a large cohort of Spanish cirrhotic patients infected with genotypes 1 and 4 

      Mariño, Zoe; Pascasio-Acevedo, Juan M.; Gallego, Adolfo; Diago, Moisés; Baliellas, Carme; Morillas, Rosa; Prieto, Martín; Moreno, José M.; Sánchez-Antolín, Gloria; Vergara, Mercedes; Forné, Monserrat; Fernández, Inmaculada; Castro-Iglesias, Ángeles; Pascual, Sonia; Gómez, Alexandra; Castells, Lluis; Montero, José L.; Crespo, Javier; Calleja, José L.; García-Samaniego, Javier; Carrión, José A.; Arencibia, Ana C.; Blasco, Alejandro; López-Núñez, Carmen; Sánchez Ruano, Juan José; Gea-Rodríguez, Francisco; Giráldez, Álvaro; Cabezas, Joaquín; Hontangas, Vanessa; Torras, Xavier; Castellote, José; Romero-Gómez, Manuel; Turnes, Juan; Artaza, Tomás de; Narváez, Isidro; Cuervas-Mons Martínez, Valentín; Forns, Xavier (Wiley, 2017-05-08)
      [Abstract] Background and Aims. Hepatitis C (HCV) therapy with Sofosbuvir (SOF)/Simeprevir (SMV) in clinical trials and real‐world clinical practice, showed high rates of sustained virological response (SVR) in non‐cirrhotic ...