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Prediction of compound-target interaction using several artificial intelligence algorithms and comparison with a consensus-based strategy
(BMC, 2024-03-07)
[Absctract]: For understanding a chemical compound’s mechanism of action and its side effects, as well as for drug discovery, it is crucial to predict its possible protein targets. This study examines 15 developed ...
El funcionamiento en la vida diaria de los niños con trastorno del espectro del autismo: aproximación a través del uso de un cuestionario basado en la CIF(-IA)
(Asociación Española de Profesionales del Autismo, 2016-11-17)
Automatic feature extraction using genetic programming: An application to epileptic EEG classification
(Elsevier, 2011-08)
[Abstract]: This paper applies genetic programming (GP) to perform automatic feature extraction from original feature database with the aim of improving the discriminatory performance of a classifier and reducing the input ...
S2SNet: a tool for transforming characters and numeric sequences into star network topological indices in chemoinformatics, bioinformatics, biomedical, and social-legal sciences
(Bentham, 2013)
[Abstract] The study of complex systems such as proteins/DNA/RNA or dynamics of tax law systems can be carried out with the complex network theory. This allows the numerical quantification of the significant information ...
Gene Prioritization through Consensus Strategy, Enrichment Methodologies Analysis, and Networking for Osteosarcoma Pathogenesis
(M D P I AG, 2020-02-05)
[Abstract] Osteosarcoma is the most common subtype of primary bone cancer, affecting mostly adolescents. In recent years, several studies have focused on elucidating the molecular mechanisms of this sarcoma; however, its ...
Decrypting strong and weak single-walled carbon nanotubes interactions with mitochondrial voltage-dependent anion channels using molecular docking and perturbation theory
(Nature, 2017-10-16)
[Abstract] The current molecular docking study provided the Free Energy of Binding (FEB) for the interaction (nanotoxicity) between VDAC mitochondrial channels of three species (VDAC1-Mus musculus, VDAC1-Homo sapiens, ...
ANN multiscale model of anti-HIV Drugs activity vs AIDS prevalence in the US at county level based on information indices of molecular graphs and social networks
(American Chemical Society, 2014)
[Abstract] This work is aimed at describing the workflow for a methodology that combines chemoinformatics and pharmacoepidemiology methods and at reporting the first predictive model developed with this methodology. The ...
Experimental Study and ANN Dual-Time Scale Perturbation Model of Electrokinetic Properties of Microbiota
(Frontiers Science, 2017-06-30)
[Abstract] The electrokinetic properties of the rumen microbiota are involved in cell surface adhesion and microbial metabolism. An in vitro study was carried out in batch culture to determine the effects of three levels ...
Molecular Docking and Machine Learning Analysis of Abemaciclib in Colon Cancer
(BioMed Central Ltd., 2020-07-08)
[Abstract]
Background -
The main challenge in cancer research is the identification of different omic variables that present a prognostic value and personalised diagnosis for each tumour. The fact that the diagnosis is ...