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Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D₃ Analogs with Locked Mobility at C-17 

Fraga, Ramón; Len, Kateryna; Lutzing, Regis; Laverny, Gilles; Loureiro, Julián; Maestro, Miguel; Rochel, Natacha; Rodríguez-Borges, Enrique; Mouriño, Antonio (Wiley, 2021-08-11)
[Abstract] Vitamin D receptor ligands have potential for the treatment of hyperproliferative diseases and disorders related to the immune system. However, hypercalcemic effects limit their therapeutical uses and call for ...

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Author
Fraga, Ramón (1)
Laverny, Gilles (1)
Len, Kateryna (1)
Loureiro, Julián (1)
Lutzing, Regis (1)
Maestro, Miguel (1)Mouriño, Antonio (1)Rochel, Natacha (1)Rodríguez-Borges, Enrique (1)Subject
Allenes (1)
Orthoester-Claisen rearrangement (1)
Pd-catalyzed reactions (1)
Synthesis (1)
Vitamin D analogs (1)
... View MoreDate Issued2021 (1)
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