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dc.contributor.authorFacal, David
dc.contributor.authorMaseda, Ana
dc.contributor.authorPereiro Rozas, Arturo
dc.contributor.authorGandoy-Crego, Manuel
dc.contributor.authorLorenzo-López, Laura
dc.contributor.authorYanguas, Javier
dc.contributor.authorMillán-Calenti, José Carlos
dc.date.accessioned2019-01-03T08:45:47Z
dc.date.issued2018-12-07
dc.identifier.citationFacal D, Maseda A, Pereiro AX, et al. Cognitive frailty: a conceptual systematic review and an operational proposal for future research. Maturitas. 2018; 121:48-56es_ES
dc.identifier.issn0378-5122
dc.identifier.urihttp://hdl.handle.net/2183/21550
dc.description.abstract[Abstract] Objective. To analyze the definition of “cognitive frailty” and to study the conceptual and operational definitions used and their implications for empirical research. The relationships between this concept and cognitive reserve, the role of neuropathology and brain reserve, motor signs of aging and the reversibility of cognitive frailty are also discussed. Study design. Systematic review of empirical studies identified from Medline Advanced 1966, CINAHL, Web of Science, PsycINFO, and Scopus until August 2017. Main – outcome measures. Effect sizes. The quality of the articles was assessed by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Statement. Three independent reviewers participated in the study selection and data extraction. Results. Nineteen studies involving 31,707 participants met the inclusion criteria. Significant associations were reported between cognitive frailty and physical frailty or gait speed. Screening instruments were usually used to determine objective cognitive decline rather than extensive neuropsychological assessments. Educational level was the only indicator of cognitive reserve that was systematically included in the evaluation of cognitive frailty. Motor decline and gait variables were not systematically included in protocols for the assessment of cognitive frailty. Conclusions. A strong operational definition would benefit both the development of treatments to counter cognitive frailty and the assessment of treatment effectiveness. Nevertheless, since there is clear agreement regarding the importance of interventions for and the prevention of cognitive frailty, randomized controlled trials investigating the efficacy of preventive interventions are necessary.es_ES
dc.description.sponsorshipXunta de Galicia; ED431C-2017/27es_ES
dc.description.sponsorshipXunta de Galicia; ED431C 2017/49es_ES
dc.description.sponsorshipXunta de Galicia; ED431F 2017/09es_ES
dc.description.sponsorshipXunta de Galicia; IN607C 2016/08es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation.urihttps://doi.org/10.1016/j.maturitas.2018.12.006es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Españaes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectCognitive frailtyes_ES
dc.subjectCognitive aginges_ES
dc.subjectCognitive impairmentes_ES
dc.subjectPhysical frailtyes_ES
dc.subjectCognitive reservees_ES
dc.titleCognitive frailty: a conceptual systematic review and an operational proposal for future researches_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessinfo:eu-repo/semantics/embargoedAccesses_ES
dc.date.embargoEndDate2019-12-07es_ES
dc.date.embargoLift2019-12-07
UDC.journalTitleMaturitases_ES
UDC.volume121es_ES
UDC.startPage48es_ES
UDC.endPage56es_ES


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