Show simple item record

dc.contributor.authorFernández Caggiano, Mariana
dc.contributor.authorBarallobre-Barreiro, Javier
dc.contributor.authorRego-Pérez, Ignacio
dc.contributor.authorCrespo-Leiro, María Generosa
dc.contributor.authorPaniagua-Martín, María J.
dc.contributor.authorGrille Cancela, Zulaika
dc.contributor.authorBlanco García, Francisco J
dc.contributor.authorDoménech, Nieves
dc.date.accessioned2017-09-15T11:38:40Z
dc.date.available2017-09-15T11:38:40Z
dc.date.issued2013-03-23
dc.identifier.citationFernández-Caggiano M, Barallobre-Barreiro J, Rego-Pérez I, et al. Mitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in spanish population. Mitochondrion. 2013;13(4):263-268es_ES
dc.identifier.issn1567-7249
dc.identifier.issn1872-8278
dc.identifier.urihttp://hdl.handle.net/2183/19475
dc.description.abstract[Abstract] Idiopathic dilated cardiomyopathy (IDC) is a structural heart disease with strong genetic background. The different single nucleotide polymorphisms (SNPs) that constitute mitochondrial haplogroups could play an important role in IDC progression. The aim of this study was to test frequencies of mitochondrial haplogroups in healthy controls (n = 422) and IDC patients (n = 304) of a Caucasian Spanish population. To achieve this, ten major European haplogroups were identified. Frequencies and Odds Ratios for the association between IDC and haplogroups were calculated in both groups. We found that compared to healthy controls, the prevalence of haplogroup H was significantly higher in IDC patients (40.0% vs 50.7%, p-value = 0.040).es_ES
dc.description.sponsorshipInstituto de Salud Carlos III; PS09/00840es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation.urihttp://dx.doi.org/10.1016/j.mito.2013.03.005es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Españaes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectMitochondrial haplogroupses_ES
dc.subjectIdiopathic dilated cardiomyopathyes_ES
dc.subjectOxidative stresses_ES
dc.subjectReactive oxygen specieses_ES
dc.subjectSingle nucleotide polymorphismses_ES
dc.titleMitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in Spanish populationes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessinfo:eu-repo/semantics/openAccesses_ES
UDC.journalTitleMitochondriones_ES
UDC.volume13es_ES
UDC.issue4es_ES
UDC.startPage263es_ES
UDC.endPage268es_ES


Files in this item

Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record