INIBIC-OCT - Artigos: Envíos recentes
Mostrando ítems 11-15 de 21
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Potential role of sugar transporters in cancer and their relationship with anticancer therapy
(Hindawi, 2010-06-20)[Abstract] Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. ... -
A novel procedure for protein extraction from formalin-fixed paraffin-embedded tissues
(Wiley, 2011-05-18)[Abstract] Most of the archived pathological specimens in hospitals are kept as formalin-fixed paraffin-embedded tissues (FFPE) for long-term preservation. Up to now, these samples are only used for immunohistochemistry ... -
Sunitinib-induced asthenia: from molecular basis to clinical relief
(Taylor & Francis, 2011-11-01)[Abstract] Asthenia-fatigue syndrome (AFS) is defined as a persistent, subjective sense of tiredness related to cancer or its treatment and greatly impacts quality of life among cancer patients. All tyrosine kinase inhibitors, ... -
Hakai reduces cell-substratum adhesion and increases epithelial cell invasion
(BioMed Central, 2011-11-03)[Abstract] Background. The dynamic regulation of cell-cell adhesions is crucial for developmental processes, including tissue formation, differentiation and motility. Adherens junctions are important components of the ... -
Biological influence of Hakai in cancer: a 10-year review
(Springer, 2012-02-19)[Abstract] In order to metastasize, cancer cells must first detach from the primary tumor, migrate, invade through tissues, and attach to a second site. Hakai was discovered as an E3 ubiquitin-ligase that mediates the ...