Viroloxía clínica: Envíos recentes

Mostrando ítems 11-15 de 42

    • Effectiveness and Safety of Sofosbuvir/Velpatasvir ± Ribavirin vs Glecaprevir/Pibrentasvir in Genotype 3 Hepatitis C Virus Infected Patients 

      Margusino-Framiñán, Luis; Cid-Silva, Purificación; Rotea-Salvo, Sandra; Mena, Álvaro; Suárez-López, Francisco; Vázquez-Rodríguez, Pilar; Delgado, Manuel; Sanclaudio-Luhia, Ana I.; Martín-Herranz, Isabel; Castro-Iglesias, Ángeles (BMJ Publishing Group, 2020-02-07)
      [Abstract] Objectives. Sofosbuvir/velpatasvir±ribavirin (SOF/VEL±RBV) and glecaprevir/pibrentasvir (GLE/PIB) are the drug combinations of choice for treating individuals with genotype 3 hepatitis C virus (G3-HCV) infection. ...

    • Deep-Sequencing Reveals Broad Subtype-Specific HCV Resistance Mutations Associated with Treatment Failure 

      Chen, Qian; Perales, Celia; Soria, María Eugenia; García-Cehic, Damir; Gregori, Josep; Rodríguez-Frías, Francisco; Buti, M.; Crespo, Javier; Calleja, J.L.; Tabernero, David; Vila Salvador, Marta; Lázaro, Fernando; Rando-Segura, Ariadna; Nieto-Aponte, Leonardo; Llorens-Revull, Meritxell; Cortese, Maria Francesca; Fernández, Irati; Castellote, José; Niubó, Jordi; Imaz, Arkaitz; Delgado, Manuel; Cañizares, Angelina; Castro-Iglesias, Ángeles (Elsevier, 2019-12-16)
      [Abstract] A percentage of hepatitis C virus (HCV)-infected patients fail direct acting antiviral (DAA)-based treatment regimens, often because of drug resistance-associated substitutions (RAS). The aim of this study was ...

    • Effectiveness and Safety of Direct‐Acting Antivirals in Hepatitis C Infected Patients With Mental Disorders: Results in Real Clinical Practice 

      Bobadilla-Pérez, Eva; Cid-Silva, Purificación; Rodríguez‐Sotelo, Alejandro; Yáñez‐Rubal, Juan C.; Mena, Álvaro; Suárez-López, Francisco; Prieto‐Pérez, Andrea; Giménez‐Arufe, Víctor; Delgado, Manuel; Sanclaudio‐Luhia, Ana I.; Martín‐Herranz, Isabel; Castro-Iglesias, Ángeles; Margusino-Framiñán, Luis (Willey Online Library, 2020-03-17)
      [Abstract] The aim of this study is to analyze the effectiveness and safety of direct‐acting antivirals (DAAs) in psychiatric patients with chronic hepatitis C (CHC). Secondary objectives included adherence and drug‐drug ...

    • Diverse large HIV-1 non-subtype B clusters are spreading among men who have sex with men in Spain 

      Delgado, Elena; Benito, Sonia; Montero, Vanessa; Cuevas, María Teresa; Fernández-García, Aurora; Sánchez-Martínez, Mónica; García-Bodas, Elena; Díez-Fuertes, Francisco; Gil, Horacio; Cañada, Javier; Carrera, Cristina; Martínez-López, Jesús; Sintes, Marcos; Pérez-Álvarez, Lucía; Thomson, Michael M.; Castro-Iglesias, Ángeles (Frontiers, 2019-08-03)
      [Abstract] In Western Europe, the HIV-1 epidemic among men who have sex with men (MSM) is dominated by subtype B. However, recently, other genetic forms have been reported to circulate in this population, as evidenced ...

    • Liver-related events and mortality among elderly patients with advanced chronic hepatitis C treated with direct-acting antivirals 

      Rodríguez-Osorio, Iria; Mena, Álvaro; Meijide, Héctor; Morano, Luis; Delgado, Manuel; Cid-Silva, Purificación; Margusino-Framiñán, Luis; Pedreira, José D.; Castro-Iglesias, Ángeles (Plos ONE, 2019-06-03)
      [Abstract] BACKGROUND: Direct-acting antivirals (DAAs) are effective in patients aged ≥65 years. However, little is known about the effects of DAAs on survival, liver decompensation and development of hepatocellular ...