• High rates of protein intake are associated with an accelerated rate of decline of residual kidney function in incident peritoneal dialysis patients 

      Otero Alonso, Pablo; Pérez-Fontán, Miguel; López Iglesias, Antía; García Falcón, María Teresa; Rodríguez-Carmona, Ana (Oxford Academic, 2019-01-04)
      [Abstract] Background Preservation of residual kidney function (RKF) is a relevant objective in peritoneal dialysis (PD) patients. The influence of dietary protein intake (PI) on this variable has not been adequately ...
    • Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3 

      Heras, Violeta; Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Sánchez-Tapia, María J.; Ruiz-Pino, Francisco; Roa, Juan; Lara-Chica, Maribel; Morrugares-Carmona, Rosario; Jouy, Nathalie; Abreu, Ana P.; Prevot, Vincent; Belsham, Denise; Vázquez, María J.; Calzado, Marco A.; Pinilla, Leonor; Gaytán, Francisco; Latronico, Ana C.; Kaiser, Ursula B.; Castellano, Juan M.; Tena-Sempere, Manuel (Public Library of Science (PLoS), 2019-11-07)
      [Abstract] Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; ...
    • Importance of exercise in the control of metabolic and inflammatory parameters at the moment of onset in type 1 diabetic subjects 

      Martínez-Ramonde, T.; Alonso, N.; Cordido, Fernando; Cervelló, E.; Cañizares, Angelina; Martínez-Peinado, P.; Sempere, J.M.; Roche, E. (Thieme, 2014-05-05)
      [Abstract] The onset of type 1 diabetes coincides with the final phase of β-cell destruction. In some cases, this period is characterized by the presence of a functional reserve of β-cells, favouring an adequate metabolic ...
    • Influence of Age on Rat Bone-Marrow Mesenchymal Stem Cells Potential 

      Fafián Labora, Juan Antonio; Fernández-Pernas, Pablo; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Oreiro, Natividad; Sangiao-Alvarellos, Susana; Mateos, Jesús; Arufe, M.C. (Nature, 2015-11-19)
      [Abstract] Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone ...
    • Low serum levels of vitamin D are associated with progression of subclinical atherosclerotic vascular disease in peritoneal dialysis patients: a prospective, multicenter study 

      Pérez-Fontán, Miguel; Borrás Sans, Mercé; Bajo Rubio, María Auxiliadora; Rodríguez Carmona, Ana; Betriu, Angels; Valdivielso, José Manuel; Fernández, Elvira (Karger, 2017-02-25)
      [Abstract] Background: The prevalence of subclinical atherosclerosis and the main predictors of progression of this condition in patients undergoing peritoneal dialysis (PD) have been insufficiently investigated. Objectives ...
    • Mitochondrial Dysfunction Plays a Relevant Role in Pathophysiology of Peritoneal Membrane Damage Induced by Peritoneal Dialysis 

      Ramil-Gómez, Olalla; Rodríguez-Carmona, Ana; Fernández-Rodríguez, Jennifer Adriana; Pérez-Fontán, Miguel; Ferreiro-Hermida, Tamara; López Pardo, Mirian; Pérez-López, Teresa; López-Armada, María José (MDPI, 2021-03-13)
      [Abstract] Preservation of the peritoneal membrane is an essential determinant of the long-term outcome of peritoneal dialysis (PD). Epithelial-to-mesenchymal transition (EMT) plays a central role in the pathogenesis of ...
    • Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test 

      Pena-Bello, Lara; Seoane-Pillado, Teresa; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Cordido, María; Cordido, Fernando (Elsevier para European Federation of Internal Medicine, 2017-06-09)
      [Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...
    • Peritoneal dialysis Is an independent factor associated to lower intima media thickness in dialysis patients free from previous cardiovascular disease 

      Borrás, Mercé; Cambray, Serafí; Crespo-Masip, María; Pérez-Fontán, Miguel; Bozic, Milica; Bermúdez-López, Marcelino; Fernández, Elvira; Betriu, Ángels; Valdivieso, José M. (Frontiers, 2018-12-04)
      [Abstract] Carotid intima media thickness (cIMT) displays prognostic value as a marker of cardiovascular risk in dialysis patients. However, few data are available regarding the impact of dialysis modality on cIMT. The aim ...
    • Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients 

      Pérez-Fontán, Miguel; Rodríguez Carmona, Ana; Barreda, D.; López-Muñiz, Andrés; Blanco-Castro, N.; García Falcón, María Teresa (Karger, 2010)
      [Abstract] Background: Peritoneal protein excretion (PPE) is a potential marker of the outcome in peritoneal dialysis (PD) patients. Method: Observational study of a cohort of 269 patients starting PD in a single unit. ...
    • Peritoneal total protein transport assessed from peritoneal equilibration tests using different dialysate glucose concentrations 

      Gomes, Ana Marta; Pérez-Fontán, Miguel; Rodríguez-Carmona, Ana; López-Muñiz, Andrés; Fernández-Villar, Marcos; Peteiro-Cartelle, Javier; García-Falcón, Teresa (SAGE, 2010-09)
      [Abstract] Background: The peritoneal equilibration test (PET) permits assessment of peritoneal protein transport, but this potential marker of outcome in peritoneal dialysis (PD) patients lacks adequate standardization. ...
    • Peritoneal water transport characteristics of diabetic patients undergoing peritoneal dialysis: a longitudinal study 

      Fernandes, Ana; Ribera-Sánchez, Roi; Rodríguez Carmona, Ana; López-Iglesias, Antía; Leite-Costa, Natacha; Pérez-Fontán, Miguel (Karger, 2017-06-21)
      [Abstract] Background: Volume overload is frequent in diabetics undergoing peritoneal dialysis (PD), and may play a significant role in the excess mortality observed in these patients. The characteristics of peritoneal ...
    • Persistent overhydration associates a significant risk of peritoneal infection with enteric germs in patients treated with peritoneal dialysis 

      Fiel, D. Carvalho; Pérez-Fontán, Miguel; López-Iglesias, Antía; Bravo González-Blas, L.; García Gago, L.; García Falcón, María Teresa; Rodríguez-Carmona, Ana (Elsevier, 2019-11)
      [Abstract] Background: Overhydration (OH) complicates frequently the clinical course of Peritoneal Dialysis (PD) patients, and keeps a controversial association with the risk of peritoneal infection. The main objective ...
    • Pituitary MRI features in acromegaly resulting from ectopic GHRH secretion from a neuroendocrine tumor: analysis of 30 cases 

      Potorac, Iulia; Bonneville, Jean-François; Daly, Adrian F.; de Herder, Wouter; Fainstein-Day, Patricia; Chanson, Philippe; Korbonits, Marta; Cordido, Fernando; Lamback, Elisa Baranski; Abid, Mohamed; Raverot, Véronique; Raverot, Gerald; Anda Apiñániz, Emma; Caron, Philippe; Du Boullay, Helene; Bidlingmaier, Martin; Bolanowski, Marek; Laloi-Michelin, Marie; Borson-Chazot, Francoise; Chabre, Olivier; Christin-Maitre, Sophie; Briet, Claire; Díaz-Soto, Gonzalo; Bonneville, Fabrice; Castinetti, Frederic; Gadelha, Mônica R.; Oliveira Santana, Nathalie; Stelmachowska-Banaś, Maria; Gudbjartsson, Tomas; Villar-Taibo, Rocío; Zornitzki, Taiba; Tshibanda, Luaba; Petrossians, Patrick; Beckers, Albert (Oxford University Press on behalf of the Endocrine Society, 2022-05-04)
      [Abstract] Context: Ectopic acromegaly is a consequence of rare neuroendocrine tumors (NETs) that secrete GHRH. This abnormal GHRH secretion drives GH and IGF-1 excess, with a clinical presentation similar to classical ...
    • Practical guidelines for diagnosis and treatment of acromegaly 

      Cordido, Fernando; García-Arnés, Juan Antonio; Marazuela, Mónica; Torres Vela, Elena (Elsevier, 2013-10)
      [Abstract] Acromegaly and gigantism are due to excess GH secretion, usually by a pituitary adenoma. It is an uncommon disease. Diagnosis is made by showing elevated GH and IGF-I levels in patients with a clinical picture ...
    • Resultados del trabajo cooperativo de los registros españoles de diálisis peritoneal: análisis de 12 años de seguimiento 

      Remón Rodríguez, César; Quirós Ganga, Pedro; Portolés-Pérez, José; Gómez-Roldán, Carmina; Miguel-Carrasco, Alfonso; Borrás Sans, Mercé; Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Sánchez-Álvarez, Emilio; Rodríguez Suárez, Carmen (Sociedad Española de Nefrología, 2014)
      [Resumen] Introducción y objetivos: Actualmente no existe un registro que muestre en su conjunto y globalidad la realidad de la diálisis peritoneal (DP) en España. Sin embargo, para distintos congresos y reuniones se ha ...
    • Serum levels of the adipomyokine irisin in patients with chronic kidney disease 

      Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Sangiao-Alvarellos, Susana; García Falcón, María Teresa; Pena-Bello, Lara; López-Muñiz, Andrés; Cordido, Fernando (Elsevier, 2016-12-14)
      [Abstract] Background. Irisin is an adipomyokine with claimed anti-obesity and anti-diabetic effects. This hormone has been insufficiently studied in patients with advanced chronic kidney disease (CKD). Objective. To ...
    • Situación de la infección por SARS-CoV-2 en pacientes en tratamiento renal sustitutivo. Informe del Registro COVID-19 de la Sociedad Española de Nefrología (SEN) 

      Sánchez-Álvarez, J. Emilio; Pérez-Fontán, Miguel; Jiménez Martín, Carlos; Blasco Pelícano, Miquel; Cabezas Reina, Carlos Jesús; Sevillano Prieto, Ángel M.; Melilli, Edoardo; Crespo Barrios, Marta; Macía Heras, Manuel; Pino y Pino, María Dolores del (Elsevier, 2020-04-16)
      [Resumen] Introducción. La reciente aparición de la pandemia por el coronavirus SARS-CoV-2 ha impactado de forma muy importante en la población general. Los pacientes en tratamiento renal sustitutivo (TRS) no han sido ...
    • The SEEN comprehensive clinical survey of adult obesity: executive summary 

      Ballesteros-Pomar, María D.; Vilarrasa, Nuria; Rubio Herrera, Miguel Ángel; Barahona, María José; Bueno, Marta; Caixás, Assumpta; Calañas Continente, Alfonso; Ciudin, Andreea; Cordido, Fernando; Hollanda, Ana de; Díaz, María Jesús; Flores, Lliliam; García Luna, Pedro Pablo; García Pérez-Sevillano, Fernando; Goday, Albert; Lecube, Albert; López Gómez, Juan José; Miñambres, Inka; Morales Gorria, María José; Morinigo, Rosa; Nicolau, Joana; Pellitero, Silvia; Salvador, Javier; Valdés, Sergio; Bretón Lesmes, Irene (Elsevier, 2021-04-09)
      [Abstract] Obesity is one of the great challenges in healthcare nowadays with important implications for health so requiring comprehensive management. This document aims to establish practical and evidence-based recommendations ...
    • The Spanish Society of Nephrology (SENEFRO) commentary to the Spain GBD 2016 report: Keeping chronic kidney disease out of sight of health authorities will only magnify the problem 

      Ortiz, Alberto; Sánchez-Niño, María Dolores; Crespo-Barrio, Marta; De-Sequeira-Ortiz, Patricia; Fernández-Giráldez, Elvira; García-Maset, Rafael; Macía-Heras, Manuel; Pérez-Fontán, Miguel; Rodríguez-Portillo, Mariano; Salgueira-Lazo, Mercedes; Sánchez-Álvarez, Emilio; Santamaría-Olmo, Rafael; Simal-Blanco, Fernando; Pino-Pino, María Dolores (Elsevier, 2018-11-28)
      [Abstract] The Global Burden of Disease (GBD) study measures the health of populations worldwide and by country on an annual basis and aims at helping guide public policy on health issues. The GBD estimates for Spain in ...
    • Thyroid Function Alteration in Obesity and the Effect of Bariatric Surgery 

      Cordido, María; Juiz-Valiña, Paula; Urones Cuesta, Paula; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2022-02-28)
      [Abstract] The most common endocrine disease in obesity is hypothyroidism and secondary endocrine alterations, including abnormal thyroid function, are frequent in obesity. It is unclear whether impaired thyroid function ...