• Central Resistance to Thyroid Hormones in Morbidly Obese Subjects is Reversed after Bariatric Surgery-Induced Weight Loss 

      Juiz-Valiña, Paula; Cordido, María; Outeiriño-Blanco, Elena; Pértega-Díaz, Sonia; Varela-Rodríguez, Bárbara María; García-Brao, María Jesús; Mena, Enrique; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2020-01-28)
      [Abstract] Endocrine abnormalities are common in obesity, including altered thyroid function. The altered thyroid function of obesity may be due to a mild acquired resistance to the thyroid hormone. The aim of this study ...
    • Changes in hypothalamic expression of the Lin28/let-7 system and related MicroRNAs during postnatal maturation and after experimental manipulations of puberty 

      Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Ruiz-Pino, Francisco; Navarro, V.M.; Sánchez-Garrido, M.A.; León, Silvia; Diéguez, Carlos; Cordido, Fernando; Matagne, V.; Dissen, G.A.; Ojeda, S.R.; Pinilla, Leonor; Tena-Sempere, Manuel (Endocrine Society, 2013)
      [Abstract] Lin28 and Lin28b are related RNA-binding proteins that inhibit the maturation of miRNAs of the let-7 family and participate in the control of cellular stemness and early embryonic development. Considerable ...
    • Circulating levels of irisin in hypopituitary and normal subjects 

      Pena-Bello, Lara; Pértega-Díaz, Sonia; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Eiras-Leal, Raquel; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Pérez-Fontán, Miguel; Cordido, María; Cordido, Fernando (PLoS ONE, 2016-07-29)
      [Abstract] Context. The recently identified myokine irisin conveys some of the benefits of exercise. Hypopituitarism with adult growth hormone deficiency (HP) is a situation characterized by decreased GH secretion and an ...
    • Clinical significance of T2-weighted sequence intensity on magnetic resonance imaging in clinically non-functioning pituitary adenomas 

      Iglesias, Pedro; Biagetti, Betina; Araújo-Castro, Marta; Alcázar, Victoria; Guerrero-Pérez, Fernando; Riveiro, Noelia; Casteràs, Anna; García Gómez, Carlos; García Izquierdo, Belén; Viedma Torres, Víctor; Pascual-Corrales, Eider; Pavón, Isabel; Villabona, Carles; Cordido, Fernando; Díez, Juan J. (Thieme, 2023-12)
      [Abstract] Background Little is known about the relationship between signal intensity patterns on T2-weighted magnetic resonance imaging (MRI) in non-functioning pituitary adenomas (NFPAs). Objective In this study, the ...
    • Compared decline of residual kidney function in patients treated with automated peritoneal dialysis and continuous ambulatory peritoneal dialysis: a multicenter study 

      Pérez-Fontán, Miguel; Remón Rodríguez, César; Borrás Sans, Mercé; Sánchez Álvarez, Emilio; da Cunha Naveira, Marta; Quirós Ganga, Pedro; López-Calviño, Beatriz; Rodríguez Suárez, Carmen; Rodríguez-Carmona, Ana (Karger, 2015-01-08)
      [Abstract] BACKGROUND: There is controversy concerning the compared rates of decline of residual kidney function (RKF) in patients treated with continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal ...
    • Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome 

      Margusino-Framiñán, Luis; Pértega-Díaz, Sonia; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Pita-Gutiérrez, Francisco; Pita-Fernández, Salvador; Cordido, Fernando (Elsevier, 2015-08-20)
      [Abstract] Context. There is no uniform standard of care for acromegaly. Due to the high costs involved, steps must be taken to ensure the cost-effective delivery of treatment. Objective. Taking the results of an earlier ...
    • Craniopharyngioma in the elderly: a multicenter and nationwide study in Spain 

      Iglesias, Pedro; Nocete, Ignacio; Moure Rodríguez, María Dolores; Venegas-Moreno, Eva; Ares, Jessica; Biagetti, Betina; Rodríguez Berrocal, Víctor; Guerrero-Pérez, Fernando; Vicente, Almudena; Villar-Taibo, Rocío; Cordido, Fernando; Paja, Miguel; Glerean, Mariela; González Rivera, Natividad; Dios Fuentes, Elena; Blanco, Concepción; Álvarez-Escolá, Crisitina; Martín, Tomás; Webb, Susan M.; Bernabeu, Ignacio; Villabona, Carles; Soto-Moreno, Alfonso; Gaztambide, Sonia; Díez, Juan José (Karger, 2020-10-09)
      [Abstract] Background: Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. Aim: To evaluate the clinicopathological features and therapeutic ...
    • Deregulation of miR-324/KISS1/kisspeptin in early ectopic pregnancy: mechanistic findings with clinical and diagnostic implications 

      Romero-Ruiz, Antonio; Avendaño, María S.; Domínguez, Francisco; Lozoya, Teresa; Molina-Abril, Helena; Sangiao-Alvarellos, Susana; Gurrea, Marta; Lara-Chica, Maribel; Fernández-Sánchez, Manuel; Torres-Jiménez, Encarnación; Perdices-López, Cecilia; Abbara, Ali; Steffani, Liliana; Calzado, Marco A.; Dhilo, Waljit S.; Pellicer, Antonio; Tena-Sempere, Manuel (Elsevier, 2019-05)
      [Abstract] BACKGROUND: Ectopic pregnancy is a life-threatening condition for which novel screening tools that would enable early accurate diagnosis would improve clinical outcomes. Kisspeptins, encoded by KISS1, play ...
    • Effect of cabergoline on tumor remnant after surgery in nonfunctioning pituitary adenoma 

      Iglesias, Pedro; Biagetti, Betina; Araújo-Castro, Marta; Alcázar, Victoria; Guerrero-Pérez, Fernando; Rivero, Noelia; Casteràs, Anna; García Izquierdo, Belén; García Gómez, Carlos; Viedma Torres, Víctor; Pascual-Corrales, Eider; Pavón, Isabel; Villabona, Carles; Cordido, Fernando; Díez, Juan J. (Springer, 2022-11-10)
      [Abstract] Background: In recent years, dopamine agonists (DAs) have become an attractive therapeutic option to prevent both tumor growth and post-surgical tumor remnant growth in clinically non-functioning pituitary adenoma ...
    • Effect of dialysis modality and other prescription factors on peritoneal protein excretion in peritoneal dialysis 

      Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Pértega-Díaz, Sonia; López-Calviño, Beatriz; López-Muñiz, Andrés; García-Falcón, Teresa (Elsevier, 2012-11)
      [Abstract] Background: There is a deficit of information regarding the factors that influence peritoneal protein excretion (PPE) during PD therapy. In particular, the effects of the modality of PD and other conditions of ...
    • Effect of ghrelin on glucose-insulin homeostasis: therapeutic implications 

      Sangiao-Alvarellos, Susana; Cordido, Fernando (Hindawi, 2010)
      [Abstract] Ghrelin is a 28-amino-acid peptide that displays a strong growth hormone- (GH-) releasing activity through the activation of the growth hormone secretagogue receptor (GHSR). The first studies about role of ghrelin ...
    • Effect of weight loss after bariatric surgery on thyroid-stimulating hormone levels in euthyroid patients with morbid obesity 

      Juiz-Valiña, Paula; Outeiriño-Blanco, Elena; Pértega-Díaz, Sonia; Varela-Rodríguez, Bárbara María; García-Brao, María Jesús; Mena, Enrique; Pena-Bello, Lara; Cordido, María; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2019-05-20)
      [Abstract] Obesity is associated with several endocrine abnormalities, including thyroid dysfunction. The objective of this study was to investigate the effect of weight loss after bariatric surgery on thyroid-stimulating ...
    • Effectiveness of lanreotide autogel 120 mg at extended dosing intervals for acromegaly 

      Bernabéu, Ignacio; Fajardo, Carmen; Marazuela, Mónica; Cordido, Fernando; Venegas, Eva; Pablos Velasco, Pedro de; Piedrola Maroto, Gonzalo; Olvera Márquez, María del Pilar; Pavón de Paz, Isabel; Carvalho, Davide; Romero, Carmen; De la Cruz, Guillermo; Álvarez Escolá, Cristina (Springer, 2020-07-28)
      [Abstract] Purpose. Recent data indicate that extended dosing intervals (EDIs) with lanreotide autogel 120 mg are effective and well-received among patients with acromegaly who have achieved biochemical control with monthly ...
    • Enterococcal peritonitis in peritoneal dialysis patients: last name matters 

      Pérez-Fontán, Miguel; Rodríguez-Carmona, Ana; Rodríguez-Mayo, María (SAGE, 2011)
    • Evaluation of Thyroid Hormone Replacement Dosing in Morbidly Obese Hypothyroid Patients after Bariatric Surgery-Induced Weight Loss 

      Juiz-Valiña, Paula; Cordido, María; Outeiriño-Blanco, Elena; Pértega-Díaz, Sonia; Urones Cuesta, Paula; García-Brao, María Jesús; Mena, Enrique; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2021-08-19)
      [Abstract] The most frequent endocrine disease in obese patients is hypothyroidism. To date, there are no clear data regarding what happens to the dose of levothyroxine (LT4) after bariatric surgery (BS). The objective of ...
    • Executive summary of the consensus document on hypophysitis of the Neuroendocrinology Area of Knowledge of the Spanish Society of Endocrinology and Nutrition 

      Iglesias, Pedro; Biagetti, Betina; Guerrero-Pérez, Fernando; Vicente, Almudena; Cordido, Fernando; Díez, Juan J. (Elsevier, 2023-03)
      [Abstract] The term hypophysitis is used to designate a heterogeneous group of pituitary conditions characterized by the presence of inflammatory infiltration of the adenohypophysis, neurohypophysis, or both. Although ...
    • Factors associated with therapeutic response in acromegaly diagnosed in the elderly in Spain 

      Biagetti, Betina; Iglesias, Pedro; Villar-Taibo, Rocío; Moure, María-Dolores; Paja, Miguel; Araújo-Castro, Marta; Ares, Jessica; Álvarez-Escola, Cristina; Vicente, Almudena; Álvarez Guivernau, Élia; Novoa-Testa, Iria; Guerrero Pérez, Fernando; Cámara, Rosa; Lecumberri, Beatriz; García Gómez, Carlos; Bernabéu, Ignacio; Manjón, Laura; Gaztambide, Sonia; Cordido, Fernando; Webb, Susan; Webb, Susan M.; Menéndez-Torre, Edelmiro Luis; Díez, Juan J.; Simó, Rafael; Puig-Domingo, Manel (Frontiers, 2022-09-16)
      [Abstract] Context: Some reports suggest that acromegaly in elderly patients has a more benign clinical behavior and could have a better response to first-generation long-acting somatostatin receptor ligands (SRL). However, ...
    • FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle 

      Varela-Rodríguez, Bárbara María; Pena-Bello, Lara; Juiz-Valiña, Paula; Vidal Bretal, Beatriz; Cordido, Fernando; Sangiao-Alvarellos, Susana (Nature, 2016-07-19)
      [Abstract] Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum ...
    • Getting the right patient on the right renal replacement therapy 

      Pérez-Fontán, Miguel; Rodríguez-Carmona, Ana; López-Muñiz, Andrés; García-Falcón, Teresa (Karger, 2012-05)
      [Abstract] Adequate selection of the modality of renal replacement therapy (RRT), ideally based on well-planned predialysis care, informed decision by the patient and timely initiation of dialysis, is essential to optimize ...
    • Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism 

      Sangiao-Alvarellos, Susana; Helming, Steffen; Vázquez, María J.; Klussmann, Sven; Cordido, Fernando (Elsevier, 2011)
      [Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ...