Now showing items 119-138 of 174

    • Popeye's sign, heart disease, and amyloidosis 

      Barge-Caballero, Gonzalo; Gargallo-Fernández, Paula; Barge-Caballero, Eduardo; Crespo-Leiro, María Generosa (Elsevier, 2019-02-21)
    • POT1 and damage response malfunction trigger acquisition of somatic activating mutations in the VEGF pathway in cardiac angiosarcomas 

      Calvete, Oriol; García-Pavía, Pablo; Domínguez, Fernando; Mosteiro, Lluc; Pérez-Cabornero, Lucía; Cantalapiedra, Diego; Zorio, Esther; Ramón y Cajal, Teresa; Crespo-Leiro, María Generosa; Teulé, Álex; Lázaro, Conxi; Morente, Manuel; Urioste, Miguel; Benitez, Javier (American Heart Association, 2019-09-17)
      [Abstract] Background Mutations in the POT1 gene explain abnormally long telomeres and multiple tumors including cardiac angiosarcomas (CAS). However, the link between long telomeres and tumorigenesis is poorly ...
    • Preoperative toxoplasma gondii serostatus does not affect long-term survival of cardiac transplant recipients: analysis of the Spanish Heart Transplantation Registry 

      Barge-Caballero, Eduardo; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Brossa-Loidi, Vicens; Rangel-Sousa, Diego; Gómez-Bueno, Manuel; Farrero-Torres, Marta; Díaz-Molina, Beatriz; Delgado-Jiménez, Juan F.; Martínez-Sellés, Manuel; López-Granados, Amador; De la Fuente-Galán, Luis; González-Costello, José; Garrido-Bravo, Iris P.; Blasco-Peiró, Teresa; Rábago, Gregorio; González-Vílchez, Francisco (Elsevier, 2017-10-07)
      [Abstract] Background. It's unclear whether pre-transplant T. gondii seropositivity is associated with impaired survival in heart transplant recipients. Objectives. To test the above-mentioned hypothesis in the Spanish ...
    • Prevalence and correlates of cost-related medication nonadherence to immunosuppressive drugs after heart transplantation: the international multicenter cross-sectional bright study 

      Schönfeld, Sandra; Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Russell, Cynthia L.; Crespo-Leiro, María Generosa; De Geest, Sabina (Wolters Kluwer, 2020)
      [Abstract] Background: Cost-related medication nonadherence (CRMNA) refers to not taking medications as prescribed because of difficulties paying for them. Objectives: The aims of this study were (1) to assess the ...
    • Prevalence of tricuspid regurgitation after orthotopic heart transplantation and its evolution in the follow-up period: a long-term study 

      López-Vilella, Raquel; Paniagua-Martín, María J.; González-Vílchez, Francisco; Donoso Trenado, Víctor; Barge-Caballero, Eduardo; Sánchez-Lázaro, Ignacio; Aller Fernández, Ana Vanesa; Martínez-Dolz, Luis; Crespo-Leiro, María Generosa; Almenar-Bonet, Luis (Elsevier, 2022-10-26)
      [Abstract] Background. Tricuspid regurgitation (TR) after heart transplant (HT) can be an important complication depending on its etiology and severity. This study aims to analyze the prevalence of TR, the causes, and its ...
    • Prevalence, characteristics and prognostic impact of aortic valve disease in patients with heart failure and reduced, mildly reduced, and preserved ejection fraction: an analysis of the ESC Heart Failure Long-Term Registry 

      Shahim, Bahira; Shahim, Angiza; Adamo, Marianna; Chioncel, Ovidiu; Benson, Lina; Crespo-Leiro, María Generosa; Anker, Stefan D.; Coats, Andrew J.S.; Filippatos, Gerasimos; Lainscak, Mitja; McDonagh, Theresa; Mebazaa, Alexandre; Piepoli, Massimo F.; Rosano, Giuseppe M.C.; Ruschitzka, Frank; Savarese, Gianluigi; Seferovic, Petar; Volterrani, Maurizio; Segovia-Cubero, Javier; Amir, Offer; Palic, Benjamin; magg, Aldo P.; Metra, Marco; Lund, Lars H. (Wiley, 2023-05-21)
      [Abstract] Aims: To assess the prevalence, clinical characteristics, and outcomes of patients with heart failure (HF) with or without moderate to severe aortic valve disease (AVD) (aortic stenosis [AS], aortic regurgitation ...
    • Prevalence, Incidence, and Outcomes of Hyperkalaemia in Patients with Chronic Heart Failure and Reduced Ejection Fraction from a Spanish Multicentre Study: SPANIK-HF Design and Baseline Characteristics 

      Delgado-Jiménez, Juan F.; Segovia-Cubero, Javier; Almenar-Bonet, Luis; Juan-Bagudá, Javier de; Lara-Padrón, Antonio; García-Pinilla, José Manuel; Bonilla-Palomas, Juan Luis; López-Fernández, Silvia; Mirabet-Pérez, Sonia; Gómez-Otero, Inés; Castro-Fernández, Antonio; Díaz-Molina, Beatriz; Goirigolzarri-Artaza, Josebe; Rincón-Pérez, Luis Miguel; Pascual-Figal, Domigo A.; Anguita-Sánchez, Manuel; Muñiz, Javier; Crespo-Leiro, María Generosa (MDPI, 2022-02-22)
      [Abstract] Hyperkalaemia is a growing concern in the treatment of patients with heart failure and reduced ejection fraction (HFrEF) as it limits the use of some prognostic-modifying drugs and has a negative impact on ...
    • Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology 

      Piepoli, Massimo Francesco; Adamo, Marianna; Barison, Andrea; Bestetti, Reinaldo B.; Biegus, Jan; Böhm, Michael; Butler, Javed; Carapetis, Jonathan; Ceconi, Claudio; Chioncel, Ovidiu; Coats, Andrew; Crespo-Leiro, María Generosa; de Simone, Giovanni; Drexel, Heinz; Emdin, Michele; Farmakis, Dimitros; Halle, Martin; Heymans, Stephane; Jaarsma, Tiny; Jankowska, Ewa; Lainscak, Mitja; Lam, Carolyn S.P.; Løchen, Maja-Lisa; Lopatin, Yuri; Maggioni, Aldo; Matrone, Benedetta; Metra, Marco; Noonan, Katharine; Pina, Ileana; Prescott, Eva; Rosano, Giuseppe; Seferovic, Petar M.; Sliwa, Karen; Stewart, Simon; Uijl, Alicia; Vaartjes, Ilonca; Vermeulen, Roel; Verschuren, W.M.; Volterrani, Maurizio; Von Haehling, Stephan; Hoes, Arno (Oxford Academic, 2022-01-27)
      [Abstract] The heart failure epidemic is growing and its prevention, in order to reduce associated hospital readmission rates and its clinical and economic burden, is a key issue in modern cardiovascular medicine. The ...
    • Prognostic implications of atrial fibrillation in heart failure with reduced, mid-range, and preserved ejection fraction: a report from 14 964 patients in the European Society of Cardiology Heart Failure Long-Term Registry 

      Zafrir, Barak; Lund, Lars H.; Laroche, Cecile; Ruschitzka, Frank; Crespo-Leiro, María Generosa; Coats, Andrew J.S.; Anker, Stefan; Filippatos, Gerasimos; Seferovic, Petar M.; Maggioni, Aldo P.; Mora Martín, Manuel De; Polonski, Lech; Silva-Cardoso, José; Amir, Offer (Oxford, 2018-10-15)
      [Abstract] Aim. To investigate the characteristics long-term prognostic implications (up to ∼2.2 years) of atrial fibrillation (AF) compared to sinus rhythm (SR), between acute and chronic heart failure (HF) with reduced ...
    • Prognostic Implications of Pathogenic Truncating Variants in the TTN Gene 

      Peña-Peña, Maria Luisa; Ochoa, Juan Pablo; Barriales-Villa, Roberto; Cicerchia, Marcos; Palomino-Doza, Julián; Salazar-Mediguchia, Joel; Lamounier, Arsonval; Trujillo-Quintero, Juan Pablo; García-Giustiniani, Diego; Fernández, Xusto; Ortiz-Genga, Martín; Monserrat, Lorenzo; Crespo-Leiro, María Generosa (Elsevier, 2020-05-01)
      [Abstract] Introduction and objectives: TTN gene truncating variants (TTNtv) are a frequent cause of dilated cardiomyopathy (DCM). However, there are discrepant data on the associated prognosis. Our objectives were to ...
    • Prognostic significance of heart rate and its long-term trend in cardiac transplant patients 

      Barge-Caballero, Eduardo; Jiménez-López, Jesús; Chávez-Leal, Sergio; Barge-Caballero, Gonzalo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Cuenca-Castillo, José J.; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier para Sociedad Española de Cardiología, 2015-04-11)
      [Abstract] Introduction and objectives. The aim of the present study was to examine the prognostic significance of heart rate and its trend in heart transplantation. Methods. This observational study enrolled 170 patients ...
    • Prognostic value of discharge heart rate in acute heart failure patients: more relevant in atrial fibrillation? 

      Agra Bermejo, Rosa; Pascual Figal, Domingo A.; Gude Sampedro, Francisco; Delgado-Jiménez, Juan F.; Vidal-Pérez, Rafael Carlos; Gómez Otero, Inés; Ferrero-Gregori, Andreu; Álvarez-García, Jesús; Worner Diz, Fernando; Segovia, Jesús; Crespo-Leiro, María Generosa; Cinca Cuscullola, Juan; Fernández-Avilés, Francisco; González-Juanatey, J.R. (Elsevier, 2020-02)
      [Abstract] Aims. The prognostic impact of heart rate (HR) in acute heart failure (AHF) patients is not well known especially in atrial fibrillation (AF) patients. The aim of the study was to evaluate the impact of admission ...
    • Prognostic value of serum lactate levels in patients undergoing urgent heart transplant: a subanalysis of the ASIS-TC spanish multicenter study 

      Couto-Mallón, David; González-Vílchez, Francisco; Almenar-Bonet, Luis; Díaz-Molina, Beatriz; Segovia-Cubero, Javier; González-Costello, José; Delgado-Jiménez, Juan F.; Castel-Lavilla, María A.; Crespo-Leiro, María Generosa; Rangel-Sousa, Diego; Martínez-Sellés, Manuel; Rábago, Gregorio; De-la-Fuente Galán, Luis; Blasco-Peiró, Teresa; Hervás-Sotomayor, Daniela; Garrido-Bravo, Iris P.; Mirabet, Sonia; Muñiz, Javier; Barge-Caballero, Eduardo (Elsevier, 2018-05-30)
      [Abstract] Introduction and objectives. To study the prognostic value of serum lactate in patients under temporary preoperative mechanical circulatory support who underwent urgent heart transplant. Methods. We conducted ...
    • Prognostic value of the nutritional risk index in heart transplant recipients 

      Barge-Caballero, Eduardo; García-López, Fernando; Marzoa Rivas, Raquel; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Solla-Buceta, Miguel; Velasco-Sierra, Carlos; Pita-Gutiérrez, Francisco; Herrera-Noreña, José M.; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier para Sociedad Española de Cardiología, 2017-02-10)
      [Abstract] Introduction and objectives. To study the prognostic impact of preoperative nutritional status, as assessed through the nutritional risk index (NRI), on postoperative outcomes after heart transplantation ...
    • Protocolo diagnóstico de las miocardiopatías genéticas 

      Martínez-Paz, E.; Barge-Caballero, Gonzalo; Crespo-Leiro, María Generosa (Elsevier, 2017-10-29)
      [Resumen] Características generales. Las miocardiopatías genéticas engloban un grupo heterogéneo de enfermedades. Algunas afectan de forma aislada al músculo cardíaco, en otros casos forman parte del espectro de una ...
    • Pulmonary vascular remodeling and prognosis in patients evaluated for heart transplantation: insights from the OCTOPUS-CHF study 

      Martínez-Solano, Jorge; Gutiérrez-Ibañes, Enrique; Ortiz-Bautista, Carlos; García-Cosío, María Dolores; Sarnago-Cebada, Santiago; Díaz-Molina, Beatriz; Pascual, Isaac; Oteo-Domínguez, Juan Francisco; Gómez-Bueno, Manuel; Calviño-Santos, Ramón; Crespo-Leiro, María Generosa; Gómez-Hospital, Joan Antoni; Díez-López, Carles; García-Lara, Juan; Garrido-Bravo, Iris P.; de la Fuente-Galán, Luis; López-Díaz, Javier; Mirabet-Pérez, Sonia; Martínez-Sellés, Manuel (MDPI, 2022-12-06)
      [Abstract] Objective: In patients with advanced heart failure, the intravascular optical coherence tomography (OCT) of subsegmental pulmonary artery measurements is correlated with right heart catheterization parameters. ...
    • Rationale and design of the ESC Heart Failure III Registry – Implementation and discovery 

      Lund, Lars H.; Crespo-Leiro, María Generosa; Laroche, Cecile; García-Pinilla, José M.; Bennis, Ahmed; Vataman, Eleonora B.; Polovina, Marija; Radovanovic, Slavica; Apostolovic, Svetlana R.; Asanin, Milika; Gackowski, Andrzej; Kaplon-Cieslicka, Agnieszka; Cabac-Pogorevici, Irina; Anker, Stefan D.; Chioncel, Ovidiu; Coats, Andrew J.S.; Filippatos, Gerasimos; Lainscak, Mitja; Mcdonagh, Theresa; Mebazaa, Alexandre; Metra, Marco; Piepoli, Massimo; Rosano, Giuseppe M.; Ruschitzka, Frank; Savarese, Gianluigi; Seferovic, Petar; Lung, Bernard; Popescu, Bogdan A.; Maggioni, Aldo P. (John Wiley & Sons, 2023-11-21)
      [Abstract] Aims: Heart failure outcomes remain poor despite advances in therapy. The European Society of Cardiology Heart Failure III Registry (ESC HF III Registry) aims to characterize HF clinical features and outcomes ...
    • Redefining the molecular rejection states in 3230 heart transplant biopsies: relationships to parenchymal injury and graft survival 

      Halloran, Phillip F.; Madill-Thomsen, Katelynn; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martín; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Jamil, Aayla; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Melenovsky, Vojtech; Patel, Jignesh; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas (Elsevier, 2024-03-26)
      [Abstract] The first-generation Molecular Microscope (MMDx) system for heart transplant endomyocardial biopsies used expression of rejection-associated transcripts (RATs) to diagnose not only T cell-mediated rejection ...
    • Reduced mitochondrial pyruvate carrier expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin 

      López-Vázquez, Paula; Fernández-Caggiano, Mariana; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Paniagua-Martín, María J.; Enríquez-Vázquez, Daniel; Vázquez-Rodríguez, José M.; Doménech, Nieves; Crespo-Leiro, María Generosa (Frontiers, 2024-03-08)
      [Abstract] Introduction and objectives: Mitochondrial pyruvate carrier (MPC) mediates the entry of pyruvate into mitochondria, determining whether pyruvate is incorporated into the Krebs cycle or metabolized in the cytosol. ...
    • Registro Español de Trasplante Cardiaco. XXVI Informe Oficial de la Sección de Insuficiencia Cardiaca y Trasplante Cardiaco de la Sociedad Española de Cardiología (1984-2014) 

      González-Vílchez, Francisco; Segovia Cubero, Javier; Almenar, Luis; Crespo-Leiro, María Generosa; Arizón-del-Prado, José M.; Villa, Adolfo; Delgado-Jiménez, Juan F.; Roig, Eulàlia; Lage, Ernesto; González-Costello, José (Elsevier para Sociedad Española de Cardiología, 2015-10-09)
      [Resumen] Introducción y objetivos. Se presentan las características y resultados del trasplante cardiaco en España desde que empezó su actividad en mayo de 1984. Métodos. Se realiza un análisis descriptivo de las ...