Buscar
Mostrando ítems 1-10 de 11
Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis
(Multidisciplinary Digital Publishing Institute, 2016)
Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs). Although the genotoxic and cytotoxic responses to OA ...
Okadaic Acid: More than a Diarrheic Toxin
(Multidisciplinary Digital Publishing Institute, 2013)
Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be consumed by humans causing alimentary ...
Okadaic Acid Meet and Greet: An Insight into Detection Methods, Response Strategies and Genotoxic Effects in Marine Invertebrates
(Multidisciplinary Digital Publishing Institute, 2013)
Harmful Algal Blooms (HABs) constitute one of the most important sources of contamination in the oceans, producing high concentrations of potentially harmful biotoxins that are accumulated across the food chains. One such ...
Evaluation of Okadaic Acid-Induced Genotoxicity in Human Cells Using the Micronucleus Test and γH2AX Analysis
(Taylor and Francis, 2011-06-27)
[Abstract] Marine algal blooms have become a public health concern due to increasing frequency in the environment and severity of exposure consequences. Human intoxications produced by phycotoxins occur globally through ...
Okadaic Acid Induces Morphological Changes, Apoptosis and Cell Cycle Alterations in Different Human Cell Types
(Royal Society of Chemistry (Gran Bretaña), 2011-03-28)
[Abstract] Okadaic acid (OA) is a marine toxin produced by dinoflagellate species which is frequently accumulated in molluscs usual in the human diet. The exact action mechanism of OA has not been described yet and the ...
Induction of Oxidative DNA Damage by the Marine Toxin Okadaic Acid Depends on Human Cell Type
(Elsevier, 2011-03-01)
[Abstract] The marine toxin okadaic acid (OA) is the main representative of diarrhoeic shellfish poisoning (DSP) toxins. Its ingestion induces nausea, vomiting, diarrhoea and abdominal ache. It has also been found to trigger ...
Cytogenetic Effects Induced by Prestige Oil on Human Populations: The Role of Polymorphisms in Genes Involved in Metabolism and DNA Repair
(Elsevier, 2008-04-18)
[Abstract] The spill from the oil tanker Prestige (NW Spain, November 2002) was perhaps the biggest ecological disaster that happened worldwide in the last decades. As a consequence of this catastrophe a general concern ...
Assessment of Okadaic Acid Effects on Cytotoxicity, DNA Damage and DNA Repair in Human Cells
(Elsevier, 2010-05-26)
[Abstract] Okadaic acid (OA) is a phycotoxin produced by several types of dinoflagellates causing diarrheic shellfish poisoning (DSP) in humans. Symptoms induced by DSP toxins are mainly gastrointestinal, but the intoxication ...
The Organic Selenium Compound Selenomethionine Modulates Bleomycin-Induced DNA Damage and Repair in Human Leukocytes
(Springer, 2009-05-08)
[Abstract] The objective of this work was to evaluate the effects of selenomethionine (SeMet) on the induction, repair, and persistence of DNA damage in human leukocytes challenged with bleomycin (BLM). Comet assay was ...