• Evaluation of Plakophilin-3 mRNA as a biomarker for detection of circulating tumor cells in gastrointestinal cancer patients 

      Valladares-Ayerbes, Manuel; Díaz-Prado, Silvia; Reboredo, Margarita; Medina, Vanessa; Lorenzo-Patiño, María J.; Iglesias-Díaz, Pilar; Haz, Mar; Pértega-Díaz, Sonia; Santamarina, Isabel; Blanco, Moisés; Quindós-Varela, María; Figueroa, Angélica; Antón-Aparicio, Luis M. (American Association for Cancer Research, 2010-05-25)
      [Abstract] Background: This study aims to assess Plakophilin-3 (PKP3) as a surrogate biomarker of circulating tumor cells in patients with gastrointestinal cancer. Methods: The primary aim is to estimate the diagnostic ...
    • Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer 

      Valladares-Ayerbes, Manuel; Blanco, Moisés; Reboredo, Margarita; Lorenzo-Patiño, María J.; Iglesias-Díaz, Pilar; Haz, Mar; Díaz-Prado, Silvia; Medina, Vanessa; Santamarina, Isabel; Pértega-Díaz, Sonia; Figueroa, Angélica; Antón-Aparicio, Luis M. (MDPI, 2012-04-05)
      [Abstract] We aim to estimate the diagnostic performances of anterior gradient homolog-2 (AGR2) and Leucine-rich repeat-containing-G-protein-coupled receptor 5 (LGR5) in peripheral blood (PB) as mRNA biomarkers in colorectal ...
    • Prostate cancer and Hedgehog signalling pathway 

      Antón-Aparicio, Luis M.; García Campelo, Rosario; Casinello Espinosa, J.; Valladares-Ayerbes, Manuel; Reboredo, Margarita; Díaz-Prado, Silvia; Aparicio Gallego, Guadalupe (Springer, 2007-08-02)
      [Abstract] The Hedgehog (Hh) family of intercellular signalling proteins have come to be recognised as key mediators in many fundamental processes in embryonic development. Their activities are central to the growth, ...