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Toxo: A Library for Calculating Penetrance Tables of High-Order Epistasis Models
(BioMed Central Ltd., 2020-04-09)
[Abstract]
Background
Epistasis is defined as the interaction between different genes when expressing a specific phenotype. The most common way to characterize an epistatic relationship is using a penetrance table, which ...
Evaluation of Existing Methods for High-Order Epistasis Detection
(Institute of Electrical and Electronics Engineers, 2020-10-15)
[Abstract]
Finding epistatic interactions among loci when expressing a phenotype is a widely employed strategy to understand the genetic architecture of complex traits in GWAS. The abundance of methods dedicated to the ...
PyToxo: a Python tool for calculating penetrance tables of high-order epistasis models
(BMC, 2022)
[Abstract] Background
Epistasis is the interaction between different genes when expressing a certain phenotype. If epistasis involves more than two loci it is called high-order epistasis. High-order epistasis is an area ...
A SIMD Algorithm for the Detection of Epistatic Interactions of Any Order
(Elsevier, 2022)
[Abstract] Epistasis is a phenomenon in which a phenotype outcome is determined by the interaction of genetic variation at two or more loci and it cannot be attributed to the additive combination of effects corresponding ...
Fiuncho: a program for any-order epistasis detection in CPU clusters
(Springer, 2022)
[Abstract]: Epistasis can be defined as the statistical interaction of genes during the expression of a phenotype. It is believed that it plays a fundamental role in gene expression, as individual genetic variants have ...