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Conjugation of different immunogenic enterococcal vaccine target antigens leads to extended strain coverage
(Oxford University Press, 2019-07-09)
[Abstract] Enterococci have emerged as important nosocomial pathogens due to their resistance to the most commonly used antibiotics. Alternative treatments or prevention options are aimed at polysaccharides and surface-related ...
Cytotoxic furanoditerpenes from the sponge Spongia tubulifera collected in the Mexican Caribbean
(MDPI, 2019-07-16)
[Abstract] Two new spongian furanoditerpenes, 3β-hydroxyspongia-13(16),14-dien-2-one (1) and 19-dehydroxy-spongian diterpene 17 (2), along with five known terpenes, the spongian furanoditerpenes 9-nor-3-hydroxyspongia-3, ...
Subcellular duplex DNA and G‐quadruplex interaction profiling of a hexagonal PtII metallacycle
(Wiley, 2019-04-19)
[Abstract] Metal‐driven self‐assembly afforded a multitude of fascinating supramolecular coordination complexes (SCCs) with applications as catalysts, host–guest, and stimuli‐responsive systems. However, the interest in ...
Anti-Inflammatory Effects of 5α,8α-Epidioxycholest-6-en-3β-ol, a Steroidal Endoperoxide Isolated from Aplysia depilans, Based on Bioguided Fractionation and NMR Analysis
(MDPI, 2019-06-03)
[Abstract:] Sea hares of "Aplysia" genus are recognized as a source of a diverse range of metabolites. 5α,8α-Endoperoxides belong to a group of oxidized sterols commonly found in marine organisms and display several ...
Thinking Outside the Blue Box: From Molecular to Supramolecular PH-Responsiveness
(Royal Society of Chemistry, 2019-10-23)
[Abstract] We present herein the development of a new polycationic cyclophane: the “red box”, second in a series of hydrazone-based analogues of the well-known organic receptor cyclobis(paraquat-p-phenylene)cyclophane ...
Synthesis of D–A–A and D–A–D Pyrimidine π-Systems Using Triorganoindium Reagents: Optical, Vibrational, and Electrochemical Studies
(American Chemical Society (ACS), 2019-06-26)
[Abstract] A series of donor–acceptor–acceptor (D–A–A) and donor–acceptor–donor (D–A–D) systems based on a pyrimidine π-spacer with various substituents at the C-2 position has been successfully prepared. The synthesis ...
Thinking Outside the Blue Box: Induced Fit within a Unique Self-Assembled Polycationic Cyclophane
(ACS, 2019-02-07)
[Abstract] We present herein the development of a new polycationic molecular receptor, inspired by the ubiquitous cyclobis(paraquat-p-phenylene)cyclophane (“blue box”). Our analogue, the “white box”, has been easily ...