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Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
(Elsevier, 2012-11-10)
[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...
Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation
(Elsevier, 2020-06-07)
[Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...
Impact of short-term mechanical circulatory support with extracorporeal devices on postoperative outcomes after emergency heart transplantation: data from a multi-institutional Spanish cohort
(Elsevier, 2014-07-01)
[Abstract] Objectives.
We sought to investigate the potential impact of preoperative short-term mechanical circulatory support (MCS) with extracorporeal devices on postoperative outcomes after emergency heart transplantation ...
Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry
(Willey Online Library, 2019-12-09)
[Abstract]
Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the ...
Real World Comparison of Spironolactone and Eplerenone in Patients With Heart Failure
(Elsevier, 2022-01-06)
[Abstract] Aims. In the absence of previous direct comparative studies, we aimed to evaluate the effectiveness of spironolactone and eplerenone in patients with heart failure and reduced ejection fraction (HFrEF) in a ...
Pitx2c is reactivated in the failing myocardium and stimulates Myf5 expression in cultured cardiomyocytes
(PLoS, 2014-03-04)
[Abstract] Background. Pitx2 (paired-like homeodomain 2 transcription factor) is crucial for heart development, but its role in heart failure (HF) remains uncertain. The present study lays the groundwork implicating Pitx2 ...
Prevalence and severity of renal dysfunction among 1062 heart transplant patients according to criteria based on serum creatinine and estimated glomerular filtration rate: results from the CAPRI study
(Wiley, 2009-12-18)
[Abstract] Chronic kidney disease (CKD) is staged on the basis of glomerular filtration rate; generally, the MDRD study estimate, eGFR, is used. Renal dysfunction (RD) in heart transplant (HT) patients is often evaluated ...
Renal dysfunction after orthotopic heart transplantation: incidence, natural history, and risk factors
(Elsevier, 2003-08-30)
[Abstract] Background. Renal dysfunction is a common complication after orthotopic heart transplantation (HT). The importance of factors other than exposure to immunosuppressive drugs is unclear. The purpose of this study ...
