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Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation

Suárez-Fuentetaja, Natalia; Doménech, Nieves; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Grille Cancela, Zulaika; Pombo-Otero, Jorge; Muñiz, Javier; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier, 2012-11-10)

[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...

In-hospital postoperative infection after heart transplantation: risk factors and development of a novel predictive score

Fernández-Ugidos, Paula; Barge-Caballero, Eduardo; Gómez-López, Rocío; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Iglesias-Gil, Carmen; Aller-Fernández, Vanesa; González-Barbeito, Miguel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2019-05-11)

[Abstract] Introduction: Infection is one of the most significant complications following heart transplantation (HT). The aim of this study was to identify specific risk factors for early postoperative infections in HT ...

Incidence, Risk Factors and Prognostic Impact of Cytomegalovirus Infection After Heart Transplantation

Méndez-Eirín, Elizabet; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Grille Cancela, Zulaika; Blanco-Canosa, Paula; Cañizares-Castellanos, Angelina; González Barbeito, Miguel; Aller Fernández, Ana Vanesa; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-03-20)

[Abstract] Introduction and objectives. To assess the risk factors of CMV infection after heart transplant (HT) and its influence on long-term prognosis. Methods. We conducted a retrospective single-centre study of ...

Determinants of maximal oxygen uptake in patients with heart failure

Roibal-Pravio, J.; Barge-Caballero, Eduardo; Barbeito Caamaño, Cayetana; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pardo-Martínez, Patricia; Grille Cancela, Zulaika; Blanco-Canosa, Paula; García-Pinilla, José Manuel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-03-27)

[Abstract] Aims Maximum oxygen uptake (VO₂max) is an essential parameter to assess functional capacity of patients with heart failure (HF). We aimed to identify clinical factors that determine its value, as they have not ...

Prognostic significance of heart rate and its long-term trend in cardiac transplant patients

Barge-Caballero, Eduardo; Jiménez-López, Jesús; Chávez-Leal, Sergio; Barge-Caballero, Gonzalo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Cuenca-Castillo, José J.; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier para Sociedad Española de Cardiología, 2015-04-11)

[Abstract] Introduction and objectives. The aim of the present study was to examine the prognostic significance of heart rate and its trend in heart transplantation. Methods. This observational study enrolled 170 patients ...

Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation

Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)

[Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...

Impact of short-term mechanical circulatory support with extracorporeal devices on postoperative outcomes after emergency heart transplantation: data from a multi-institutional Spanish cohort

Barge-Caballero, Eduardo; Almenar-Bonet, Luis; Villa-Arranz, Adolfo; Pérez-Villa, Félix; Segovia Cubero, Javier; Delgado-Jiménez, Juan F.; González-Vílchez, Francisco; Manito-Lorite, Nicolás; De la Fuente-Galán, Luis; Brossa-Loidi, Vicens; Lambert Rodríguez, José Luis; Pacual-Figal, Domingo; Lage-Gallé, Ernesto; Arizón-del-Prado, José M.; Sanz-Julve, Marisa; Muñiz, Javier; Crespo-Leiro, María Generosa (Elsevier, 2014-07-01)

[Abstract] Objectives. We sought to investigate the potential impact of preoperative short-term mechanical circulatory support (MCS) with extracorporeal devices on postoperative outcomes after emergency heart transplantation ...

Advanced heart failure: a position statement of the Heart Failure Association of the European Society of Cardiology

Crespo-Leiro, María Generosa; Metra, Marco; Lund, Lars H.; Milicic, Davor; Costanzo, Maria Rosa; Filippatos, Gerasimos; Gustafsson, Finn; Tsui, Steven; Barge-Caballero, Eduardo; De Jonge, Nicolaas; Frigerio, Maria; Hamdan, Righab; Hasin, Tal; Hülsmann, Martin; Nalbantgil, Sanem; Potena, Luciano; Bauersachs, Johann; Gkouziouta, Aggeliki; Ruhparwar, Arjang; Ristic, A.D.; Straburzynska-Migaj, Ewa; McDonagh, Theresa; Seferovic, Petar M.; Ruschitzka, Frank (Wiley, 2018-05-27)

[Abstract] This article updates the Heart Failure Association of the European Society of Cardiology (ESC) 2007 classification of advanced heart failure and describes new diagnostic and treatment options for these patients. ...

Paroxysmal bradyarrhythmias are frequent among heart transplant recipients with unexplained syncope: a study based on implantable loop recorders

Martínez-Paz, E.; Barge-Caballero, Eduardo; Álvarez-Roy, Laura; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Mosquera-Pérez, Ignacio; Pérez-Álvarez, Luisa; Muñiz, Javier; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2017-12-13)

Estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco: ¿un factor pronóstico independiente?

Barge-Caballero, Eduardo; Berbeito-Caamaño, Cayetana; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Herrera-Noreña, José M.; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2016-08-31)

[Resumen] Introducción y objetivos. Analizar la influencia pronóstica del estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco (TC). Métodos. Se realizó un estudio retrospectivo unicéntrico ...

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