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Cell therapy and tissue engineering for cartilage repair
(IntechOpen, 2018-02-14)
[Abstract] The integrity of the articular cartilage is necessary for the proper functioning of the diarthrodial
joint. The self-repair capacity of this tissue is very limited and, currently, there
is no effective treatment ...
Cone-beam CT-guided lung biopsies: results in 94 patients
(MDPI, 2020-12-10)
[Abstract] Background: The aim of this study was to evaluate the diagnostic capacity of Cone-Beam computed tomography (CT)-guided transthoracic percutaneous biopsies on lung lesions in our setting and to detect risk factors ...
Reduced levels of H₂S in diabetes-associated osteoarthritis are linked to hyperglycaemia, Nrf-2/HO-1 signalling downregulation and chondrocyte dysfunction
(MDPI, 2022-03-25)
[Abstract] Different findings indicate that type 2 diabetes is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Changes in the ...
Higher synovial immunohistochemistry reactivity of IL-17A, Dkk1, and TGF-β1 in patients with early psoriatic arthritis and rheumatoid arthritis could predict the use of biologics
(MDPI, 2024-04-08)
[Abstract] Background: Delay in diagnosis and therapy in patients with arthritis commonly leads to progressive articular damage. The study aimed to investigate the immunohistochemical reactivity of synovial cytokines ...
Concordance between pressure platform and pedigraph
(MDPI, 2021-12-09)
[Abstract] Objectives: Determine the concordance between two methods of obtaining the plantar footprint (pedigraph and pressure platform). Methods: A descriptive, cross-sectional, observational study of prevalence was ...
Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process
(Elsevier, 2021-12)
[Abstract] Objective: Physical function is one of the Outcome Measures in Rheumatology (OMERACT) core outcome domains for hand osteoarthritis studies. Our aim was to select appropriate instrument(s) to measure this domain, ...
Women’s satisfaction with childbirth and postpartum care and associated variables
(Universidade de São Paulo, 2021-06-09)
[Abstract] Objective: To determine the level of satisfaction with childbirth and the postpartum period.
Method: This is a longitudinal, observational study. Clinical variables of the patients and delivery were collected, ...
Mitochondrial biogenesis: a potential therapeutic target for osteoarthritis
(Elsevier, 2020-05-14)
[Abstract] Mitochondrial dysfunction of human articular chondrocytes is considered a hallmark of cartilage degradation and OA pathogenesis. Due to the huge number of cellular processes in which mitochondria is implicated, ...
Defective chaperone-mediated autophagy is a hallmark of joint disease in patients with knee osteoarthritis
(Elsevier, 2023-03-08)
[Abstract] Objective: Defects in autophagy contribute to joint aging and Osteoarthritis (OA). Identifying specific autophagy types could be useful for developing novel treatments for OA.
Design: An autophagy-related ...
