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Multistage Detection of Tetrodotoxin Traces in Diodon hystrix Collected in El Salvador
(MDPI, 2023-06-25)
[Abstract] This study describes a multistage methodology to detect minute amounts of tetrodotoxin in fishes, a plan that may be broadened to include other marine organisms. This methodology was applied to porcupinefish ...
Structural, Thermal and Functional Properties of a Hybrid Dicyanamide-Perovskite Solid Solution
(MDPI, 2022-06-18)
[Abstract]: In Solid-State Chemistry, a well-known route to obtain new compounds and modulate their
properties is the formation of solid solutions, a strategy widely exploited in the case of classical inorganic
perovskites ...
Combining JBCA and Marfey's methodology to determine the absolute configuration of threonines: the case of gunungamide A, a new cyclic depsipeptide containing chloropyrrole from the sponge Discodermia sp.
(Royal Society of Chemistry, 2018-10-29)
[Abstract] A combination of configurational analysis based on coupling constants (JBCA) and Marfey's aminoacid derivatization allowed us to distinguish between the different possible diastereoisomers of threonines in ...
Datura stramonium Flowers as a Potential Natural Resource of Bioactive Molecules: Identification of Anti-Inflammatory Agents and Molecular Docking Analysis
(MDPI, 2023-07-04)
[Abstract] The present study investigated the antioxidant, antibacterial, antiviral and anti-inflammatory activities of different aerial parts (flowers, leaves and seeds) of Datura stramonium. The plant material was extracted ...
The Outer Membrane Protein FstC of Aeromonas salmonicida subsp. salmonicida Acts as Receptor for Amonabactin Siderophores and Displays a Wide Ligand Plasticity. Structure–Activity Relationships of Synthetic Amonabactin Analogues
(American Chemical Society, 2019-09-26)
[Abstract] Amonabactins are a group of four related catecholate siderophores produced by several species of the genus Aeromonas, including A. hydrophila and the fish pathogen A. salmonicida subsp. salmonicida. Although the ...
Luminescent Ln(III)-Metallopeptide Sensors for Monitoring Pseudomonas aeruginosa Elastase B Activity in Complex Biological Media
(American Chemical Society, 2024-09-06)
[Abstract] The detection and monitoring of Pseudomonas aeruginosa and its virulence factors, such as the LasB protease, are crucial for managing bacterial infections. Traditional fluorescent sensors for this protease face ...
A Bio-inspired Hypoxia Sensor using HIF1a-Oxygen-Dependent Degradation Domain
(Nature, 2019-05-08)
[Abstract] Functional imaging has become an important tool in oncology because it not only provides information about the size and localization of the tumour, but also about the pathophysiological features of the tumoural ...
Convergent Total Synthesis of the Siderophore Piscibactin as Its Ga3+ Complex
(American Chemical Society, 2021-01-15)
[Abstract] The siderophore piscibactin is a key virulence factor involved in the iron uptake of pathogenic bacteria Photobacterium damselae subsp. piscicida and Vibrio anguillarum, responsible for the fish diseases ...
Solid-Phase Zincke Reaction for the Synthesis of Peptide-4,4′-bipyridinium Conjugates
(Thieme, 2020-02)
[Abstract] We present herein the development of a new synthetic strategy for the conjugation of 4,4′-bipyridinium derivatives into peptide scaffolds. The methodology, based on the development of a solid-phase version of ...
The Fish Pathogen Vibrio ordalii Under Iron Deprivation Produces the Siderophore Piscibactin
(MDPI, 2019-09-03)
[Abstract] Vibrio ordalii is the causative agent of vibriosis, mainly in salmonid fishes, and its virulence mechanisms are still not completely understood. In previous works we demonstrated that V. ordalii possess several ...
