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Now showing items 21-27 of 27

A novel procedure for protein extraction from formalin-fixed paraffin-embedded tissues

Rodríguez-Rigueiro, Teresa; Valladares-Ayerbes, Manuel; Haz, Mar; Blanco, Moisés; Aparicio Gallego, Guadalupe; Fernández-Puente, Patricia; Blanco García, Francisco J; Lorenzo-Patiño, María J.; Antón-Aparicio, Luis M.; Figueroa, Angélica (Wiley, 2011-05-18)

[Abstract] Most of the archived pathological specimens in hospitals are kept as formalin-fixed paraffin-embedded tissues (FFPE) for long-term preservation. Up to now, these samples are only used for immunohistochemistry ...

Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition

Antón-Aparicio, Luis M.; Abella Cajigal, Vanessa; Valladares-Ayerbes, Manuel; Figueroa, Angélica (Springer, 2013-05-29)

[Abstract] Epithelial-to-mesenchymal transition (EMT), one of the crucial steps for carcinoma cells to acquire invasive capacity, results from the disruption of cell–cell contacts and the acquisition of a motile mesenchymal ...

A new scenario in metastatic renal cell carcinoma: a SOG‑GU consensus

Vázquez Estévez, Sergio; Anido Herranz, Urbano; Lázaro Quintela, Martín; Fernández Calvo, Ovidio; Fernández-Núñez, Natalia; Dios Álvarez, N. de; Varela, V.; Campos Balea, B.; Agraso, S.; Areses, M. C.; Iglesias, L.; Blanco, Moisés; Maciá, S.; Antón-Aparicio, Luis M. (Springer, 2020-02-15)

[Abstract] Background This article describes and compares approved targeted therapies and the newer immunotherapy agents. Materials and methods This article especially performs an in-depth review of currently available ...

Radium-223 dichloride: a new paradigm in the treatment of prostate cancer

Anido Herranz, Urbano; Fernández Calvo, Ovidio; Afonso Afonso, Francisco Javier; Rodríguez Martínez de Llano, Sofía; Lázaro Quintela, Martín; León Mateos, Luis; Vázquez Estévez, Sergio; Antón-Aparicio, Luis M. (Taylor & Francis, 2015-01-02)

[Abstract] Radionuclides have been widely used for cancer treatment. Recently, new research about radium-223 dichloride has been conducted in prostate cancer, which reveals that it is the first radiopharmaceutical to ...

Experience with Sunitinib in metastatic renal cell carcinoma (mRCC) patients: pooled analysis from 3 Spanish observational prospective studies

Castellano, Daniel; Maroto, José Pablo; Espinosa, Enrique; Grande, Enrique; Bolós Fernández, Victoria; Llinares, Julia; Esteban, Emilio; González del Alba, Aránzazu; Climent, Miguel Ángel; Arranz, José Ángel; Méndez, María José; Fernández Parra, Eva; Antón-Aparicio, Luis M.; Bayona, Cristina; Gallegos, Isabel; Gallardo, Enrique; Samaniego, Luz; García Donas, Jesús (Taylor & Francis, 2017-08-28)

[Abstract] Background: A pivotal, randomized, phase III trial demonstrated a statistically significant superiority of sunitinib over interferon-α in metastatic renal cell carcinoma (mRCC) patients. Objective: To evaluate ...

Effect of gender on patients with non-small-cell lung cancer treated with immune checkpoint inhibitors: a real-world study

Calleja-Chucla, Teresa; Cordeiro González, Patricia; Martínez-Pradeda, Alejandro; Pértega-Díaz, Sonia; Margusino-Framiñán, Luis; Antolín Novoa, Silvia (MDPI, 2025-02-11)

[Abstract] Objective: To evaluate the differences in overall survival (OS) and progression-free survival (PFS) between men and women with non-small-cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs) ...

Circulating levels of GDF15, MMP7 and miR-200c as a poor prognostic signature in gastric cancer

Blanco, Moisés; Tarrío, Nuria; Reboredo, Margarita; Haz, Mar; García, Jorge; Quindós-Varela, María; Figueroa, Angélica; Antón-Aparicio, Luis M.; Calvo, Lourdes; Valladares-Ayerbes, Manuel (Future Science, 2014-06-20)

[Abstract] Aim: To analyze GDF15 and MMP7 serum levels as diagnostic biomarkers in gastric cancer (GC) patients. The prognostic value of GDF15 and MMP7 serum levels in combination with miR-200c blood expression was also ...