Search
Now showing items 1-10 of 51
Prediction of Breast Cancer Proteins Involved in Immunotherapy, Metastasis, and RNA-Binding Using Molecular Descriptors and Artifcial Neural Networks
(Springer Nature, 2020-05-22)
[Abstract]
Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein expression
deregulation, signaling pathway alterations, hormone disruption, ethnicity and environmental
determinants are involved. ...
General machine learning model, review, and experimental-theoretic study of magnolol activity in enterotoxigenic induced oxidative stress
(Bentham Science, 2017)
[Abstract] This study evaluated the antioxidative effects of magnolol based on the mouse model induced by Enterotoxigenic Escherichia coli (E. coli, ETEC). All experimental mice were equally treated with ETEC suspensions ...
Ontologies in medicinal chemistry: current status and future challenges
(Bentham Science, 2013)
[Abstract] Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, ...
A genetic algorithms-based approach for optimizing similarity aggregation in ontology matching
(Springer, 2013)
[Abstract] Ontology matching consists of finding the semantic relations between different ontologies and is widely recognized as an essential process to achieve an adequate interoperability between people, systems or ...
SNOMED2HL7: a tool to normalize and bind SNOMED CT concepts to the HL7 Reference Information Model
(Elsevier, 2017-10)
[Abstract] BACKGROUND: Current clinical research and practice requires interoperability among systems in a complex and highly dynamic domain. There has been a significant effort in recent years to develop integrative common ...
Vivencias ocupacionales de personas recientemente jubiladas en el entorno urbano de la provincia de A Coruña
(Universidad de Chile, 2017)
[Abstract] Objetivos: En la actualidad, se ha podido observar un envejecimiento progresivo de la población, lo que ha aumentado el interés acerca
de la jubilación, ya que la duración de esta será cada vez más prolongada ...
Influence of disability on maternal care
(Springer, 2015)
[Abstract] The purpose of the study was to examine how women with physical disabilities perceive the influence of their disability on maternal care during the first 3 years of their child’s life, to describe the main ...
Perturbation-Theory Machine Learning (PTML) Multilabel Model of the ChEMBL Dataset of Preclinical Assays for Antisarcoma Compounds
(American Chemical Society, 2020-10-14)
[Abstract]
Sarcomas are a group of malignant neoplasms of connective tissue with a different etiology than carcinomas. The efforts to discover new drugs with antisarcoma activity have generated large datasets of multiple ...
OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine
(Springer Nature, 2020-03-24)
[Abstract]
Breast cancer (BC) is the leading cause of cancer-related death among women and the most commonly diagnosed cancer worldwide. Although in recent years large-scale efforts have focused on identifying new therapeutic ...
Improvement of Epitope Prediction Using Peptide Sequence Descriptors and Machine Learning
(MDPI, 2019)
[Abstract] In this work, we improved a previous model used for the prediction of proteomes as new
B-cell epitopes in vaccine design. The predicted epitope activity of a queried peptide is based on its
sequence, a known ...
