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Inflammaging contributes to osteoarthritis development and human microbiota variations and vice versa: a systematic review
(Elsevier, 2024-11-28)
[Abstract] Objective: To report evidence on microbiota and its relationship with inflammaging, the innate immune system and osteoarthritis (OA) in human patients.
Design: A systematic review was performed in accordance ...
Longitudinal stability of molecular endotypes of knee osteoarthritis patients
(Elsevier, 2024-11-08)
[Abstract]
Objective: To assess the longitudinal stability of biomarker-based molecular endotypes of knee osteoarthritis (KOA) participants from APPROACH and to evaluate the consistency of findings in an independent ...
Fluctuation of bone marrow lesions and inflammatory MRI markers over 2 years and concurrent associations with quantitative cartilage loss
(Sage, 2024-10-26)
[Abstract] Objective: To assess whether change of semiquantitatively magnetic resonance imaging (MRI)-defined bone marrow lesions (BMLs) and inflammatory markers is associated with change in quantitatively-assessed cartilage ...
Suicide deaths and substance use in Spain between 2010 and 2022
(Frontiers, 2024-09-30)
[Abstract]
Background: Suicide is a serious public health problem that affects our entire country. The aim of this research was to study the variation in completed suicide rates between 2010 and 2022 in Spain and their ...
Nutritional epigenomics: bioactive dietary compounds in the epigenetic regulation of osteoarthritis
(MDPI, 2024-08-30)
of Osteoarthritis
Karla Mariuxi Villagrán-Andrade 1, Carmen Núñez-Carro 1 , Francisco J. Blanco 1,2 and María C. de Andrés 1,*
1 Unidad de Epigenética, Grupo de Investigación en Reumatología (GIR), Instituto de Investigación Biomédica
de A Coruña (INIBIC), Complexo...
Hospitalario Universitario, de A Coruña (CHUAC), Sergas, 15006 A Coruña, Spain; kariuxva@hotmail.com (K.M.V.-A.); carmen.nunez.carro@sergas.es (C.N.-C.); fblagar@sergas.es (F.J.B.) 2 Grupo de Investigación en Reumatología y Salud, Departamento de Fisioterapia...
Hospitalario Universitario, de A Coruña (CHUAC), Sergas, 15006 A Coruña, Spain; kariuxva@hotmail.com (K.M.V.-A.); carmen.nunez.carro@sergas.es (C.N.-C.); fblagar@sergas.es (F.J.B.) 2 Grupo de Investigación en Reumatología y Salud, Departamento de Fisioterapia...
First-attempt awake tracheal intubation success rate using a hyperangulated unchannelled videolaryngoscope vs. a channelled videolaryngoscope in patients with anticipated difficult airway: a randomised controlled trial
(Association of Anaesthetists, 2024-07-29)
[Abstract] Introduction: There is uncertainty about the optimal videolaryngoscope for awake tracheal intubation in patients with anticipated difficult airway. The use of channelled and unchannelled videolaryngoscopy has ...
Impact of universal use of a hyperangulated videolaryngoscope as the first option for all intubations in the ICU: a prospective before-after study
(Elsevier, 2024-07-02)
[Abstract] Background: Tracheal intubation in ICU is associated with high incidence of difficult intubations. The study aimed to investigate whether the "universal" use of a hyperangulated videolaryngoscope would increase ...
Mitochondrial role on cellular apoptosis, autophagy, and senescence during osteoarthritis pathogenesis
(MDPI, 2024-06-04)
Pathogenesis
Andrea Dalmao-Fernández 1,2 , Tamara Hermida-Gómez 1,3,4, Uxia Nogueira-Recalde 1, Ignacio Rego-Pérez 1 ,
Francisco J. Blanco-Garcia 1,5,* and Mercedes Fernández-Moreno 1,3,*
1 Grupo de Investigación en Reumatología (GIR), Instituto de...
Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade de A Coruña (UDC), 15071 A Coruña, Spain; a.d.fernandez@farmasi.uio.no (A.D.-F.); tamara.hermida.gomez@sergas.es (T.H.-G.); uxia...
Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade de A Coruña (UDC), 15071 A Coruña, Spain; a.d.fernandez@farmasi.uio.no (A.D.-F.); tamara.hermida.gomez@sergas.es (T.H.-G.); uxia...
Severity and progression of structural hand OA is not associated with progression of structural knee OA: the IMI-APPROACH cohort
(Elsevier, 2024-05)
[Abstract]. Objective. To investigate whether structural hand OA or its progression is associated with structural knee OA progression after two years in a population with symptomatic knee OA.
Methods. We used baseline and ...
Higher synovial immunohistochemistry reactivity of IL-17A, Dkk1, and TGF-β1 in patients with early psoriatic arthritis and rheumatoid arthritis could predict the use of biologics
(MDPI, 2024-04-08)
[Abstract] Background: Delay in diagnosis and therapy in patients with arthritis commonly leads to progressive articular damage. The study aimed to investigate the immunohistochemical reactivity of synovial cytokines ...
