Browsing by Author "Tasdemir, Deniz"

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Advanced Methods for Natural Products Discovery: Bioactivity Screening, Dereplication, Metabolomics Profiling, Genomic Sequencing, Databases and Informatic Tools, and Structure Elucidation

Gaudêncio, Susana P.; Bayram, Engin; Lukić Bilela, Lada; Cueto, Mercedes; Díaz-Marrero, Ana R.; Haznedaroglu, Berat Zeki; Jiménez, Carlos; Mandalakis, Manolis; Pereira, Florbela; Reyes, Fernando; Tasdemir, Deniz (MDPI, 2023-05-19)

[Abstract] Natural Products (NP) are essential for the discovery of novel drugs and products for numerous biotechnological applications. The NP discovery process is expensive and time-consuming, having as major hurdles ...
Bioactivity and Metabolome Mining of Deep-Sea Sediment-Derived Microorganisms Reveal New Hybrid PKS-NRPS Macrolactone from Aspergillus versicolor PS108-62

Magot, Florent; Soen, Gwendoline van; Buedenbender, Larissa; Li, Fengjie; Soltwedel, Thomas; Grauso, Laura; Mangoni, Alfonso; Blümel, Martina; Tasdemir, Deniz (MDPI, 2023-01-28)

[Abstract] Despite low temperatures, poor nutrient levels and high pressure, microorganisms thrive in deep-sea environments of polar regions. The adaptability to such extreme environments renders deep-sea microorganisms ...