Browsing by Author "Roma-Rodrigues, Catarina"

Now showing items 1-2 of 2

    • Evaluation of the in Vitro and in Vivo Efficacy of Ruthenium Polypyridyl Compounds Against Breast Cancer 

      Lenis Rojas, Óscar; Roma-Rodrigues, Catarina; Fernandes, Alexandra R.; Carvalho, Andreia; Cordeiro, Sandra; Guerra-Varela, Jorge; Sánchez, Laura; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández, Jesús J. (MDPI, 2021-08-18)
      [Abstract] The clinical success of cisplatin, carboplatin, and oxaliplatin has sparked the interest of medicinal inorganic chemistry to synthesize and study compounds with non-platinum metal centers. Despite Ru(II)–polypyridyl ...

    • Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Teixeira, Ricardo Gonçalves; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Alba-González, Anabel; Salamini-Montemurri, Martín; Pech-Puch, Dawrin; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2021-02-11)
      [Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...