Now showing items 1-13 of 13

    • Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian "Briareum asbestinum" 

      Pech-Puch, Dawrin; Joseph-Nathan, Pedro; Burgueño-Tapia, Eleuterio; González-Salas, Carlos; Martínez Matamoros, Diana; Pereira, David; Pereira, Renato; Jiménez, Carlos; Rodríguez, Jaime (Springer Nature, 2021-01-12)
      [Abstract] The four new briarane diterpenoids 2-butyryloxybriarane B-3 (2), 9-acetylbriarenolide S (3), briarenolide W (4), and 12-isobriarenolide P (5), along with briarane B-3 (1) and the five known diterpenes 6–10 were ...
    • Anti-inflammatory effects of 5α,8α-epidioxycholest-6-en-3β-ol, a steroidal endoperoxide isolated from "Aplysia depilans", based on bioguided fractionation and NMR analysis 

      Pereira, Renato; Pereira, David; Jiménez, Carlos; Rodríguez, Jaime; Nieto, Rosa M.; Videira, Romeu; Silva, Olga; Andrade, Paula B.; Valentão, Patrícia (MDPI, 2019-06-03)
      [Abstract:] Sea hares of "Aplysia" genus are recognized as a source of a diverse range of metabolites. 5α,8α-Endoperoxides belong to a group of oxidized sterols commonly found in marine organisms and display several ...
    • Antiviral and Antiproliferative Potential of Marine Organisms from the Yucatan Peninsula, Mexico 

      Pech-Puch, Dawrin; Berastegui-Cabrera, Judith; Pérez Povedano, Mar Anabel; Villegas-Hernández, Harold; Guillén-Hernández, Sergio; Cautain, Bastien; Reyes, Fernando; Pachón, Jerónimo; Gómez, Patricia; Rodríguez, Jaime; Jiménez, Carlos; Sánchez-Céspedes, Javier (Frontiers, 2020-08-20)
      [Abstract] Viral infections are one of the main human health problems in recent decades and the cancer remains one of the most lethal diseases worldwide. The development of new antiviral drugs for the treatment of human ...
    • Bistratamides M and N, Oxazole-Thiazole Containing Cyclic Hexapeptides Isolated from Lissoclinum bistratum Interaction of Zinc (II) with Bistratamide K 

      Urda, Carlos; Fernández, Rogelio; Rodríguez, Jaime; Pérez, Marta; Jiménez, Carlos; Cuevas, Carmen (Multidisciplinary Dixital Publishing Institute, 2017-07-01)
      [Abstract] Two novel oxazole-thiazole containing cyclic hexapeptides, bistratamides M (1) and N (2) have been isolated from the marine ascidian Lissoclinum bistratum (L. bistratum) collected in Raja Ampat (Papua Bar, ...
    • Cytotoxic furanoditerpenes from the sponge Spongia tubulifera collected in the Mexican Caribbean 

      Pech-Puch, Dawrin; Rodríguez, Jaime; Cautain, Bastien; Sandoval-Castro, Carlos Alfredo; Jiménez, Carlos (MDPI, 2019-07-16)
      [Abstract] Two new spongian furanoditerpenes, 3β-hydroxyspongia-13(16),14-dien-2-one (1) and 19-dehydroxy-spongian diterpene 17 (2), along with five known terpenes, the spongian furanoditerpenes 9-nor-3-hydroxyspongia-3, ...
    • Development of Antibacterial Steel Surfaces Through Laser Texturing 

      Villapún, Victor M.; Pérez Gómez, Astrid; Wei, W.; Dover, L. G.; Thompson, Jonathan R.; Barthels, T.; Rodríguez, Jaime; Cox, S.; González, S. (AIP Publishing, 2020-09-22)
      [Abstract] The aim of the present study was to develop novel antibacterial touch surfaces through the laser texturing optimization of stainless steel. A wide range of laser fluence (2.11 J/cm2–5.64 J/cm2) and scanning ...
    • Dolabelladienols A–C, New Diterpenes Isolated from Brazilian Brown Alga Dictyota pfaffii 

      Pardo-Vargas, Alonso; Barcelos Oliveira, Ingrid de; Stephens, Paulo Roberto Soares; Cirne-Santos, Claudio Cesar; Palmer Paixão, Izabel Christina Nunes de; Ramos, Freddy Alejandro; Jiménez, Carlos; Rodríguez, Jaime; Resende, Jackson Antonio Lamounier Camargos; Teixeira, Valeria Laneuville; Castellanos, Leonardo (Multidisciplinary Digital Publishing Institute, 2014)
      [Abstract:]The marine brown alga Dictyota pfaffii from Atol das Rocas, in Northeast Brazil is a rich source of dolabellane diterpene, which has the potential to be used in future antiviral drugs by inhibiting reverse ...
    • In vitro and in vivo assessment of the efficacy of bromoageliferin, an alkaloid isolated from the sponge "Agelas dilatata", against "Pseudomonas aeruginosa" 

      Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-06-23)
      [Abstract] The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the ...
    • Marine natural products from the Yucatan peninsula 

      Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Lenis Rojas, Oscar; Rodríguez, Jaime; Jiménez, Carlos (MDPI AG, 2020-01-16)
      [Abstract]: Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive ...
    • Marine Organisms from the Yucatan Peninsula (Mexico) as a Potential Natural Source of Antibacterial Compounds 

      Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Gómez, Patricia; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Novoa Olmedo, María Lourdes; Guillén-Hernández, Sergio; Villegas-Hernández, Harold; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-07-18)
      [Abstract] A total of 51 sponges (Porifera) and 13 ascidians (Chordata) were collected on the coast of the Yucatan Peninsula (Mexico) and extracted with organic solvents. The resulting extracts were screened for antibacterial ...
    • Natural Products from Antarctic Colonial Ascidians of the Genera Aplidium and Synoicum: Variability and Defensive Role 

      Núñez-Pons, Laura; Carbone, Marianna; Vázquez, Jennifer; Rodríguez, Jaime; Nieto, Rosa M.; Varela, María Mercedes; Gavagnin, Margherita; Ávila, Conxita
      Ascidians have developed multiple defensive strategies mostly related to physical, nutritional or chemical properties of the tunic. One of such is chemical defense based on secondary metabolites. We analyzed a series of ...
    • Relative Configuration of Micrograms of Natural Compounds Using Proton Residual Chemical Shift Anisotropy 

      Nath, Nilamoni; Fuentes-Monteverde, Juan Carlos; Pech-Puch, Dawrin; Rodríguez, Jaime; Jiménez, Carlos; Noll, Markus; Kreiter, Alexander; Reggelin, Michael; Navarro-Vázquez, Armando; Griesinger, Christian (Nature, 2020-09-01)
      [Abstract] 3D molecular structure determination is a challenge for organic compounds or natural products available in minute amounts. Proton/proton and proton/carbon correlations yield the constitution. J couplings and ...
    • Synthesis of Acetylhomoagmatine 

      Castellanos, Leonardo; Duque, Carmenza; Rodríguez, Jaime; Jiménez, Carlos (Molecular Diversity Preservation International, 2006)
      The first total synthesis of acetylhomoagmatine, a natural product isolated form the methanolic extracts from the sponge Cliona celata, is performed in four steps in a very high yield.