Browsing by Author "Robalo, M. Paula"

Now showing items 1-3 of 3

    • Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Teixeira, Ricardo Gonçalves; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Alba-González, Anabel; Salamini-Montemurri, Martín; Pech-Puch, Dawrin; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2021-02-11)
      [Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...

    • Iron(II)-cyclopentadienyl compounds are cytotoxic against colon adenocarcinoma cell lines: Ethylenebis(diphenylphosphane) vs. triphenylphosphane 

      Avecilla, Fernando; Pilon, Adhan; Rácz, Bálint; Gátszegi, Gerda T.; Spengler, Gabriella; Robalo, M. Paula; Enyedy, Éva Anna; Garcia, Maria Helena; Valente, Andreia (Elsevier, 2023)
      [Abstract] Structure-activity studies aiming to understand the role of each coligand in the formulation of new metallodrugs is an important subject. In that frame, six new compounds with general formula [Fe(η5-C5H5)(dppe ...

    • RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Carvalho, Andreia; Fernandes, Alexandra; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2018-10-19)
      [Abstract] Ruthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present the synthesis and characterization of half-sandwich ...