Browsing by Author "Montaner, Joan"

Now showing items 1-10 of 10

    • A predictive clinical-genetic model of tissue plasminogen activator response in acute ischemic stroke 

      Del Río-Espínola, Alberto; Fernández-Cadenas, Israel; Giralt, Dolors; Quiroga, Adoración; Gutiérrez-Agulló, María; Quintana, Manuel; Fernández-Álvarez, Patricia; Domingues-Montanari, Sophie; Mendióroz, Maite; Delgado, Pilar; Turck, Natacha; Ruiz Laza, Agustín; Ribó, Marc; Castellanos, María del Mar; Obach, Victor; Martínez, Sergi; Freijo Guerrero, María del Mar; Jiménez-Conde, Jordi; Cuadrado-Godia, Elisa; Roquer, Jaume; Chacón, Pilar; Martí-Fábregas, Joan; Sánchez, Jean Charles; Montaner, Joan (John Wiley & Sons, 2012-06-09)
      [Abstract] Objective: Wide interindividual variability exists in response to tissue plasminogen activator (t-PA) treatment in the acute phase of ischemic stroke. We aimed to find genetic variations associated with hemorrhagic ...

    • Blood biomarker panels for the early prediction of stroke‐associated complications 

      Faura, Júlia; Bustamante, Alejandro; Reverté, Silvia; García-Berrocoso, Teresa; Millán, Mónica; Castellanos, María del Mar; Lara-Rodríguez, Blanca; Zaragoza, Josep; Ventura, Oriol; Hernández-Pérez, María; van Eeendenburg, Cecile; Cardona, Pere; López-Cancio, Elena; Cánovas, David; Serena, Joaquín; Rubiera, Marta; Dávalos, Antoni; Montaner, Joan (American Heart Association, 2021-02-26)
      [Abstract] Background. Acute decompensated heart failure (ADHF) and respiratory tract infections (RTIs) are potentially life‐threatening complications in patients experiencing stroke during hospitalization. We aimed to ...

    • Blood biomarkers predictive of epilepsy after an acute stroke event 

      Abraira, Laura; Santamarina, Estevo; Cazorla, Sonia; Bustamante, Alejandro; Quintana, Manuel; Toledo, Manuel; Fonseca, Elena; Grau-López, Laia; Jiménez, Marta; Ciurans, Jordi; Becerra, Juan Luis; Millán, Mónica; Hernández-Pérez, María; Cardona, Pere; Terceño, Mikel; Zaragoza, Josep; Cánovas, David; Gasull, Teresa; Ustrell, Xavier; Rubiera, Marta; Castellanos, María del Mar; Montaner, Joan; Álvarez-Sabín, Jose (John Wiley & Sons, 2020-08-28)
      [Abstract] Objective: Blood biomarkers have not been widely investigated in poststroke epilepsy. In this study, we aimed to describe clinical factors and biomarkers present during acute stroke and analyze their association ...

    • Estudio de la situación actual del Teleictus en España 

      Barragán-Prieto, Ana; Pérez-Sánchez, Soledad; Castellanos, María del Mar; González-García, Alejandro; Montaner, Joan (Elsevier, 2023-08-07)
      [Resumen] Introducción. En los últimos años se ha establecido el uso del Teleictus como una herramienta fundamental para extender la atención a los pacientes con ictus agudo hasta hospitales que no disponen de neurólogos ...

    • Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: consensus document and practice guidance 

      Gil-Núñez, Antonio; Masjuan, Jaime; Montaner, Joan; Castellanos, María del Mar; Segura, Tomás; Cardona, Pere; Tembl, José Ignacio; Purroy, Francesc; Arenillas, Juan; Palacio, Enrique (Elsevier, 2021-12-11)
      [Abstract] Introduction: Patients with history of stroke or transient ischaemic attack present considerable risk of future vascular events. Reducing levels of low-density lipoprotein (LDL) cholesterol decreases the ...

    • RP11-362K2.2:RP11-767I20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma: a GWAS meta-analysis 

      Muiño, Elena; Cárcel-Márquez, Jara; Carrera, Caty; Llucià-Carol, Laia; Gallego-Fábrega, Cristina; Cullel, Natalia; Lledós, Miquel; Castillo, José; Sobrino, Tomás; Campos, Francisco; Rodríguez-Castro, Emilio; Millán, Mónica; Muñoz-Narbona, Lucía; Bustamante, Alejandro; López-Cancio Martínez, Elena; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Giralt-Steinhauer, Eva; Soriano-Tárraga, Carolina; Vives-Bauza, Cristófol; Díaz Navarro, Rosa; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fàbregas, Joan; Delgado-Mederos, Raquel; Camps-Renom, Pol; Prats-Sánchez, Luis; Guisado, Daniel; Guasch, Marina; Marin, Rebeca; Martínez-Domeño, Alejandro; Freijo Guerrero, María del Mar; Moniche Álvarez, Francisco; Cabezas, Juan Antonio; Castellanos, María del Mar; Krupinsky, Jerzy; Strbian, Daniel; Tatlisumak, Turgut; Thijs, Vincent; Lemmens, Robin; Slowik, Agnieszka; Pera, Joanna; Heitsch, Laura; Ibáñez, Laura; Cruchaga, Carlos; Dhar, Rajat; Lee, Jin-Moo; Montaner, Joan; Fernández-Cadenas, Israel (MDPI, 2021-07-16)
      [Abstract] Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase ...

    • Safety and efficacy of ApTOLL in patients with ischemic stroke undergoing endovascular treatment: a phase 1/2 randomized clinical trial 

      Hernández-Jiménez, Macarena; Abad-Santos, Francisco; Cotgreave, Ian; Gallego, Jaime; Jilma, Bernd; Flores, Alan; Jovin, Tudor G.; Vivancos, José; Hernández-Pérez, María; Molina, Carlos A.; Montaner, Joan; Casariego, Joaquín; Dalsgaard, Mads; Liebeskind, David S.; Cobo, Erik; Castellanos, María del Mar; Cardona Portela, Pere; Masjuan, Jaime; Moniche, Francisco; Tembl, José Ignacio; Terceño Izaga, Mikel; Arenillas, Juan; Calleja, Patricia; Olivot, Jean Marc; Calviere, Lionel; Henon, Hilde; Mazighi, Mikael; Piñeiro, David; Pugliese, Marco; González, Víctor M.; Moro, María Ángeles; García-Tornel, Álvaro; Lizasoain, Ignacio; Ribo, Marc (American Medical Association, 2023-06-20)
      [Abstract] Importance: ApTOLL is a TLR4 antagonist with proven preclinical neuroprotective effect and a safe profile in healthy volunteers. Objective: To assess the safety and efficacy of ApTOLL in combination with ...

    • Safety and efficacy of tirofiban in acute ischemic stroke due to tandem lesions undergoing mechanical thrombectomy: A multicenter randomized clinical trial (ATILA) protocol 

      Medina-Rodríguez, M; Moniche, Francisco; Albóniga-Chindurza, Asier de; Ortega-Quintanilla, Joaquín; Ainz-Gómez, Leire; Pardo-Galiana, Blanca; Cabezas-Rodríguez, Juan Antonio; Aguilar-Pérez, Marta; Zamora, Aynara; Delgado-Acosta, Fernando; Jiménez-Gómez, Elvira; Bravo Rey, Isabel; Oteros Fernández, Rafael; Freijo Guerrero, María del Mar; González Díaz, Eva; Escudero-Martínez, Irene; Morale Caba, Lluis; Vielba-Gómez, Isabel; Mosteiro, Sonia; Castellanos, María del Mar; Amaya Pascasio, Laura; Hidalgo, Carlos; Fernández Prudencio, Luis; Ramírez Moreno, José María; Díaz Pérez, José; Sanz-Fernández, Gema; Baena-Palomino, Pablo; Gamero-García, Miguel Ángel; Jiménez Jorge, Silvia; Rosso Fernández, Clara; Montaner, Joan; González García, Alejandro; Zapata-Arriaza, Elena (Sage, 2022-12-28)
      [Abstract] Background: In-stent thrombosis after mechanical thrombectomy (MT) worsen outcomes in acute ischemic stroke (AIS) due to tandem lesions (TL). Although an optimal antiplatelet therapy is needed, the best approach ...

    • Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma 

      Carrera, Caty; Cárcel-Márquez, Jara; Cullel, Natalia; Torres-Águila, Nuria; Muiño, Elena; Castillo, José; Sobrino, Tomás; Campos, Francisco; Rodríguez-Castro, Emilio; Llucià-Carol, Laia; Millán, Mónica; Muñoz-Narbona, Lucía; López-Cancio, Elena; Bustamante, Alejandro; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Giralt-Steinhauer, Eva; Soriano-Tárraga, Carolina; Mola-Caminal, Marina; Vives-Bauza, Cristófol; Díaz Navarro, Rosa; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fábregas, Joan; Delgado-Mederos, Raquel; Freijo Guerrero, María del Mar; Moniche, Francisco; Cabezas, Juan Antonio; Castellanos, María del Mar; Gallego-Fábrega, Cristina; González-Sánchez, Jonathan; Krupinsky, Jurek; Strbian, Daniel; Tatlisumak, Turgut; Thijs, Vincent; Lemmens, Robin; Slowik, Agnieszka; Pera, Johanna; Kittner, Steven; Cole, John; Heitsch, Laura; Ibáñez, Laura; Cruchaga, Carlos; Lee, Jin-Moo; Montaner, Joan; Fernández-Cárdenas, Israel (Oxford University Press, 2021-03-16)
      [Abstract] Haemorrhagic transformation is a complication of recombinant tissue-plasminogen activator treatment. The most severe form, parenchymal haematoma, can result in neurological deterioration, disability, and death. ...

    • Statistical analysis plan for the multicenter, open, randomized controlled clinical trial to assess the efficacy and safety of intravenous tirofiban vs aspirin in acute ischemic stroke due to tandem lesion, undergoing recanalization therapy by endovascular treatment (ATILA trial) 

      Zapata-Arriaza, Elena; Medina-Rodríguez, M; Moniche Álvarez, Francisco; Albóniga‑Chindurza, Asier de; Aguilar-Pérez, Marta; Ainz-Gómez, Leire; Baena-Palomino, Pablo; Zamora, Aynara; Pardo-Galiana, Blanca; Delgado-Acosta, Fernando; Valverde Moyano, Roberto; Jiménez-Gómez, Elvira; Bravo Rey, Isabel; Oteros Fernández, Rafael; Escudero-Martínez, Irene; Vielba-Gómez, Isabel; Morales Caba, Lluis; Díaz Pérez, José; García Molina, Estefanía; Mosteiro, Sonia; Castellanos, María del Mar; Amaya Pascasio, Laura; Hidalgo, Carlos; Freijo Guerrero, María del Mar; González-Díaz, Eva; Ramírez Moreno, José María; Fernández Prudencio, Luis; Terceño Izaga, Mikel; Bashir Viturro, Saima; Gamero-García, Miguel Ángel; Jiménez Jorge, Silvia; Rosso Fernández, Clara; Montaner, Joan; González García, Alejandro (Springer Nature, 2024-01-09)
      [Abstract] Rationale: In-stent reocclusion after endovascular therapy has a negative impact on outcomes in acute ischemic stroke (AIS) due to tandem lesions (TL). Optimal antiplatelet therapy approach in these patients ...