Browsing by Author "Martínez Matamoros, Diana"
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Absolute Configuration by Vibrational Circular Dichroism of Anti-inflammatory Macrolide Briarane Diterpenoids From the Gorgonian Briareum Asbestinum
Pech-Puch, Dawrin; Joseph-Nathan, Pedro; Burgueño-Tapia, Eleuterio; González-Salas, Carlos; Martínez Matamoros, Diana; Pereira, David; Pereira, Renato; Jiménez, Carlos; Rodríguez, Jaime (Springer Nature, 2021-01-12)[Abstract] The four new briarane diterpenoids 2-butyryloxybriarane B-3 (2), 9-acetylbriarenolide S (3), briarenolide W (4), and 12-isobriarenolide P (5), along with briarane B-3 (1) and the five known diterpenes 6–10 were ... -
Conjugation of different immunogenic enterococcal vaccine target antigens leads to extended strain coverage
Romero-Saavedra, Felipe; Laverde, Diana; Kalfopoulou, Ermioni; Martini, Cecilia; Torelli, Riccardo; Martínez Matamoros, Diana; Sanguinetti, Maurizio; Huebner, Johannes (Oxford University Press, 2019-07-09)[Abstract] Enterococci have emerged as important nosocomial pathogens due to their resistance to the most commonly used antibiotics. Alternative treatments or prevention options are aimed at polysaccharides and surface-related ... -
Detection of Aeromonas Salmonicida Subsp. Salmonicida Infection in Zebrafish by Labelling Bacteria With Gfp and a Fluorescent Probe Based on the Siderophore Amonabactin
Rodríguez-Pedrouzo, A.; Cisneros Sureda, Javier; Martínez Matamoros, Diana; Rey-Varela, Diego; Balado, Miguel; Rodríguez, Jaime; Lemos, Manuel L.; Folgueira, Mónica; Jiménez, Carlos (Elsevier, 2023-10-21)[Abstract] Zebrafish (Danio rerio) is an excellent model to study bacterial infections in fish and their treatment. We used zebrafish as a model of infection for Aeromonas salmonicida subsp. salmonicida (hereinafter A. ... -
Estudio químico de bacterias de origen marino: aislamiento de productos naturales bioactivos, proteínas recombinantes receptoras de sideróforos de bacterias patógenas en peces de acuicultura y síntesis de conjugados de sideróforos con nanopartículas magnéticas
Martínez Matamoros, Diana (2018)[Resumen] Esta Tesis Doctoral está dividida en tres partes. En la primera parte, se describe la importancia de los sistemas de captación de hierro en bacterias patógenas de peces y el uso de proteínas receptoras de ... -
FrpA Is the Outer Membrane Piscibactin Transporter in Vibrio Anguillarum: Structural Elements in Synthetic Piscibactin Analogues Required for Transport
Lages, Marta Afonso; De la Fuente, Carmen; Ageitos, Lucía; Martínez Matamoros, Diana; Rodríguez, Jaime; Balado, Miguel; Jiménez, Carlos; Lemos, Manuel L. (Springer Nature, 2021-11-18)[Abstract] Piscibactin (Pcb) is a labile siderophore widespread among Vibrionaceae. Its production is a major virulence factor of some fish pathogens such as Photobacterium damselae subsp. piscicida and Vibrio anguillarum. ... -
Preparation of Functionalized Magnetic Nanoparticles Conjugated with Feroxamine and Their Evaluation for Pathogen Detection
Martínez Matamoros, Diana; Castro-García, Socorro; Balado, Miguel; Matamoros Veloza, Adriana; Camargo-Valero, Miller Alonso; Óscar, Céspedes; Rodríguez, Jaime; Lemos, Manuel L.; Jiménez, Carlos (Royal Society of Chemistry, 2019-05-01)[Abstract] This work reports the preparation of a conjugate between amino-functionalized silica magnetite and the siderophore feroxamine. The morphology and properties of the conjugate and intermediate magnetic nanoparticles ... -
Structural Requirements for Ga3+ Coordination in Synthetic Analogues of the Siderophore Piscibactin Deduced by Chemical Synthesis and Density Functional Theory Calculations
De la Fuente, Carmen; Ageitos, Lucía; Lages, Marta Afonso; Martínez Matamoros, Diana; Forero, Abel M.; Balado, Miguel; Lemos, Manuel L.; Rodríguez, Jaime; Jiménez, Carlos (American Chemical Society, 2023-05-04)[Abstract] Stereoselective total synthesis of several analogues of piscibactin (Pcb), the siderophore produced by different pathogenic Gram-negative bacteria, was performed. The acid-sensitive α-methylthiazoline moiety was ... -
The Siderophore Piscibactin Is a Relevant Virulence Factor for Vibrio anguillarum Favored at Low Temperatures
Balado, Miguel; Lages, Marta Afonso; Fuentes-Monteverde, Juan Carlos; Martínez Matamoros, Diana; Rodríguez, Jaime; Jiménez, Carlos; Lemos, Manuel L. (Frontiers, 2018-08-02)[Abstract] Vibrio anguillarum causes vibriosis, a hemorrhagic septicaemia that affects many cultured marine fish species worldwide. Two catechol siderophores, vanchrobactin and anguibactin, were previously identified in ...
