Browsing by Author "Mariño, Ana"
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Characterization of chronic HCV infection in Northwest Spain: impact of the treatment strategic plan of the Spanish National Health Service on HCV cure
Grandal, Marta; Pernas, Berta; Mariño, Ana; Álvarez, Hortensia; Tabernilla, Andrés; Castro-Iglesias, Ángeles; Mena, Álvaro; Delgado, Manuel; Pértega-Díaz, Sonia; Poveda, Eva (Wiley, 2017-03-14)[Abstract] The aim of the study was to characterize HCV infection in Northwest Spain and assess the impact of the Spanish Strategic Plan to cure HCV infection. Overall, 387 patients were included (60.9% HIV/HCV coinfected ... -
Comparison of high ribavirin induction versus standard ribavirin dosing, plus peginterferon-α for the treatment of chronic hepatitis C in HIV-infected patients: the PERICO trial
Labarga, Pablo; Barreiro, Pablo; Silva, Alfredo da; Guardiola, Josep María; Rubio, Rafael; Aguirrebengoa, Koldo; Miralles, Pilar; Portu, Joseba; Téllez, María Jesús; Morano, Luis; Castro-Iglesias, Ángeles; Pineda, Juan Antonio; Terrón, Alberto; Hernández-Quero, José; Mariño, Ana; Ríos, María José; Echeverría, Santiago; Asensi, Víctor; Vispo, Eugenia; Soriano, Vincent (Oxford, 2012-07-17)[Abstract] BACKGROUND: Ribavirin (RBV) exposure seems to be critical to maximize treatment response in human immunodeficiency virus (HIV)-positive patients with chronic hepatitis C virus (HCV) infection. METHODS: ... -
Phylogeny and phylogeography of a recent HIV-1 subtype F outbreak among men who have sex with men in Spain deriving from a cluster with a wide geographic circulation in western Europe
Delgado, Elena; Cuevas, María Teresa; Domínguez, Francisco; Vega, Yolanda; Cabello, Marina; Fernández-García, Aurora; Pérez-Losada, Marcos; Castro-Iglesias, Ángeles; Montero, Vanessa; Sánchez, Mónica; Mariño, Ana; Álvarez, Hortensia; Ordoñez, Patricia; Ocampo, Antonio; Miralles, Celia; Pérez-Castro, Sonia; López-Álvarez, María José; Rodríguez, Raúl; Trigo, Matilde; Diz-Arén, Julio; Hinojosa, Carmen; Bachiller, Pablo; Hernáez-Crespo, Silvia; Cisterna, Ramón; Garduño, Eugenio; Pérez-Álvarez, Lucía; Thomson, Michael M. (PLOS, 2015-11-24)[Abstract] We recently reported the rapid expansion of an HIV-1 subtype F cluster among men who have sex with men (MSM) in the region of Galicia, Northwest Spain. Here we update this outbreak, analyze near full-length ... -
Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies
Grandal, Marta; Pernas, Berta; Tabernilla, Andrés; Mariño, Ana; Álvarez, Hortensia; Valcarce, Nieves; Mena, Álvaro; Castro-Iglesias, Ángeles; Pérez, Ana B.; Delgado, Manuel; Poveda, Eva (Wiley, 2018-02-10)[Abstract] The presence of resistance‐associated substitutions (RASs) at NS5A region might compromise the efficacy of Direct Acting Antiviral agents (DAAs). HCV resistance at NS5A region is mainly focused on patients with ...