Browsing by Author "Hermida-Prieto, Manuel"
Now showing items 1-15 of 15
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Analysis of the association between copy number variation and ventricular fibrillation in ST-elevation acute myocardial infarction
Lorente-Bermúdez, Roberto; Pan-Lizcano, Ricardo; Núñez, Lucía; López-Vázquez, Domingo; Rebollal-Leal, Fernando; Vázquez-Rodríguez, José Manuel; Hermida-Prieto, Manuel (MDPI, 2024-02-22)[Abstract] Sudden cardiac death due to ventricular fibrillation (VF) during ST-elevation acute myocardial infarction (STEAMI) significantly contributes to cardiovascular-related deaths. Although VF has been linked to genetic ... -
Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report
Núñez, Lucía; Crespo-Leiro, María Generosa; Marrón Liñares, Grecia Manuela; Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Hermida-Prieto, Manuel (Via Médica, 2016)[Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ... -
Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation
Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)[Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ... -
Familial Dilated Cardiomyopathy and Isolated Left Ventricular Noncompaction Associated With Lamin A/C Gene Mutations
Hermida-Prieto, Manuel; Monserrat, Lorenzo; Castro-Beiras, Alfonso; Laredo, Rafael; Soler Fernández, Rafaela; Peteiro-Vázquez, Jesús; Rodríguez, Esther; Bouzas-Zubeldia, Beatriz; Álvarez-García, Nemesio; Muñiz, Javier; Crespo-Leiro, María Generosa (Elsevier, 2004-06-23)[Abstract] LMNA mutations have been associated with familial or sporadic dilated cardiomyopathy (DC), with or without conduction system disease. We studied the LMNA gene in 67 consecutive patients with DC (18 had familial ... -
Gene expression profiling for monitoring graft rejection in heart transplant recipients
Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Hermida-Prieto, Manuel; Castro-Beiras, Alfonso (Elsevier, 2009-08-26)[Abstract] Heart transplantation is a life-prolonging therapy for many patients with stage D heart failure and other forms of advanced heart disease. However, graft rejection and/or immunosuppression-related side effects ... -
HCV clearance patterns in saliva and serum of patients with chronic HCV infection under interferon plus ribavirin therapy
Diz Dios, P.; Castro-Iglesias, Ángeles; Rodríguez, I.; Reforma, N.G.; Castro, M.; Eirea, M.; Hermida-Prieto, Manuel (Wiley, 2005-03-30)[Abstract] Statements of the problem: Hepatitis C virus (HCV)-RNA is often present in saliva of HCV-infected patients, with plasma viral load being the only known predictable factor. Interferon plus ribavirin therapy ... -
lncRNA CDKN2B-AS1 is downregulated in patients with ventricular fibrillation in acute myocardial infarction
Pan-Lizcano, Ricardo; Núñez, Lucía; Piñón-Esteban, Pablo; Aldama-López, Guillermo; Flores-Ríos, Xacobe; Calviño-Santos, Ramón; Vázquez-Rodríguez, José Manuel; Hermida-Prieto, Manuel (PLoS One, 2024-05-21)[Abstract] Ventricular fibrillation (VF) in acute myocardial infarction (AMI) is the main cause of deaths occurring in the acute phase of an ischemic event. Although it is known that genetics may play an important role in ... -
Microchimerism after heart transplantation: prevalence, predisposing factors, natural history, and prognosis
Crespo-Leiro, María Generosa; Hermida-Prieto, Manuel; Rodríguez-Fernández, José Ángel; Muñiz, Javier; Barral, S.; Paniagua-Martín, María J.; Hermida, L.F.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2002-04-10) -
Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection
Marrón Liñares, Grecia Manuela; Núñez, Lucía; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Pombo-Otero, Jorge; Paniagua-Martín, María J.; Suárez-Fuentetaja, Natalia; Cid, Javier; Grille Cancela, Zulaika; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez Rodríguez, José Manuel; Hermida-Prieto, Manuel (Elsevier, 2017-07-15)[Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ... -
Preliminary investigation on efficacy and safety of substance p-coated stent for promoting re-endothelialization: a porcine coronary artery restenosis model
Park, Dae Sung; Oh, Seok; Jin, Yu Jeong; Na, Mi Hyang; Kim, Munki; Kim, Jeong Ha; Hyun, Dae Young; Cho, Kyung Hoon; Hong, Young Joon; Kim, Ju Han; Ahn, Youngkeun; Hermida-Prieto, Manuel; Vázquez-Rodríguez, José Manuel; Gutiérrez-Chico, Juan Luis; Mariñas-Pardo, Luis; Lim, Kyung Seob; Park, Jun-Kyu; Byeon, Dae-Heung; Cho, Young-Nan; Kee, Seung-Jung; Sim, Doo Sun; Jeong, Myung Ho (Springer Nature, 2023-11-16)[Abstract] Background: Current polymer-based drug-eluting stents (DESs) have fundamental issues about inflammation and delayed re-endothelializaton of the vessel wall. Substance-P (SP), which plays an important role in ... -
Presence of Bacterial DNA in Thrombotic Material of Patients with Myocardial Infarction
Piñón-Esteban, Pablo; Núñez, Lucía; Moure, Raquel; Marrón Liñares, Grecia Manuela; Flores Ríos, Xacobe; Aldama López, Guillermo; Salgado-Fernández, Jorge; Calviño-Santos, Ramón; Rebollal-Leal, Fernando; Pan Lizcano, Ricardo Francisco; Vázquez-González, Nicolás; Bou, Germán; Tomás, María; Hermida-Prieto, Manuel; Vázquez Rodríguez, José Manuel (Nature Publishing Group, 2020-10-01)[Abstract] Infectious agents have been suggested to be involved in etiopathogenesis of Acute Coronary Syndrome (ACS). However, the relationship between bacterial infection and acute myocardial infarction (AMI) has not yet ... -
Rare variants in genes of the cholesterol pathway are present in 60% of patients with acute myocardial infarction
Pan-Lizcano, Ricardo; Mariñas-Pardo, Luis; Núñez, Lucía; Rebollal-Leal, Fernando; López-Vázquez, Domingo; Pereira, Ana; Molina-Nieto, Aránzazu; Calviño, Ramón; Vázquez-Rodríguez, José Manuel; Hermida-Prieto, Manuel (MDPI, 2022-12-17)[Abstract] Acute myocardial infarction (AMI) is a pandemic in which conventional risk factors are inadequate to detect who is at risk early in the asymptomatic stage. Although gene variants in genes related to cholesterol, ... -
Screening Mutations in Myosin Binding Protein C3 Gene in a Cohort of Patients With Hypertrophic Cardiomyopathy
Rodríguez García, María Isabel; Monserrat, Lorenzo; Ortiz, Martín; Fernández, Xusto; Cazón, Laura; Núñez, Lucía; Barriales-Villa, Roberto; Maneiro, Emilia; Veira, Elena; Castro-Beiras, Alfonso; Hermida-Prieto, Manuel (BioMed Central, 2010)[Abstract] Background. MyBPC3 mutations are amongst the most frequent causes of hypertrophic cardiomyopathy, however, its prevalence varies between populations. They have been associated with mild and late onset disease ... -
Sirolimus treatment of left ventricular hypertrophy: who, and when?
Crespo-Leiro, María Generosa; Hermida-Prieto, Manuel (Oxford, 2008-10-19) -
Systemic treatment of immune-mediated keratoconjunctivitis sicca with allogeneic stem cells improves the schirmer tear test score in a canine spontaneous model of disease
Hermida-Prieto, Manuel; Gascía-Castro, Javier; Mariñas-Pardo, Luis (MDPI, 2021-12-20)[Abstract] Keratoconjunctivitis sicca (KCS) is characterized by ocular discomfort, conjunctival hyperaemia, and corneal scarring, causing reduced aqueous tear production that can be measured using the standard Schirmer ...