Browsing by Author "Gubern-Mérida, Carme"

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Cav-1 protein levels in serum and infarcted brain correlate with hemorrhagic volume in a mouse model of thromboembolic stroke, independently of rt-PA administration

Gubern-Mérida, Carme; Comajoan, Pau; Huguet, Gemma; García-Yebenes, Isaac; Lizasoain, Ignacio; Moro, María Ángeles; Puig-Parnau, Irene; Sánchez, Juan Manuel; Serena, Joaquín; Kádár, Elisabet; Castellanos, María del Mar (Springer Nature, 2022-01-05)

[Abstract] Thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA) is currently the only FDA-approved drug for acute ischemic stroke. However, its administration is still limited due to the associated ...
MiRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis

Gubern-Mérida, Carme; Camós, Susanna; Ballesteros, Iván; Rodríguez, Rocío; Romera, Víctor G.; Cañadas, Roberto; Lizasoain, Ignacio; Moro, María Ángeles; Serena, Joaquín; Mallolas, Judith; Castellanos, María del Mar (FEBS Press, 2013-10-01)

[Abstract] Despite the large number of molecules reported as being over-expressed after ischaemia, little is known regarding their regulation. miRNAs are potent post-transcriptional regulators of gene expression, and reports ...