Browsing by Author "Fernández Sánchez, Jesús José"

Now showing items 1-4 of 4

    • Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Teixeira, Ricardo Gonçalves; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Alba-González, Anabel; Salamini-Montemurri, Martín; Pech-Puch, Dawrin; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2021-02-11)
      [Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...

    • Preparation and Characterization of Terdentate [C,N,N] Acetophenone and Acetylpyridine Hydrazone Platinacycles: A DFT Insight Into the Reaction Mechanism 

      Marcos-Cives, Ismael; Ojea, Vicente; Vázquez, Digna; Fernández Sánchez, Jesús José; Fernández, Alberto; López-Torres, Margarita; Lado Sanjurjo, Jorge; Vila, José (Royal Society of Chemistry, 2017-11-13)
      [Abstract] The reaction of N-ortho-chlorophenyl-substituted acetylpyridine hydrazones (a and d) with K2[PtCl4] (n-butanol/water, 100 °C) gave mononuclear complexes 1a and 1d with the ligands as [N,N] bidentate. In contrast, ...

    • RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Carvalho, Andreia; Fernandes, Alexandra; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2018-10-19)
      [Abstract] Ruthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present the synthesis and characterization of half-sandwich ...

    • Student-Generated Videos to Promote Understanding of Chemical Reactions 

      Fernández, Alberto; López-Torres, Margarita; Fernández Sánchez, Jesús José; Vázquez, Digna (ACS, 2023-02-03)
      [Abstract] Students were tasked with the creation of videos of ordinary reactions to promote significant learning of complex concepts underlying chemical transformations. Interactive infographics were used to deliver ...