Browsing by Author "Espada, Jesús"
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Hedgehog signalling as a target in cancer stem cells
Medina Villaamil, Vanessa; Blanco, Moisés; Díaz-Prado, Silvia; Espada, Jesús (Spirnger, 2009)[Abstract] Hedgehog (Hh) is one of the most important signalling pathways. Together with the Wnt, TGF-β/BMP and Notch pathways, it is involved in both embryonic development and adult tissue homeostasis. This is because Hh ... -
Wnt signalling and cancer stem cells
Espada, Jesús; Calvo, Moisés B.; Díaz-Prado, Silvia; Medina, Vanessa (Springer, 2009-07-15)[Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and ...