Now showing items 1-7 of 7

    • Circulating levels of GDF15, MMP7 and miR-200c as a poor prognostic signature in gastric cancer 

      Blanco, Moisés; Tarrío, Nuria; Reboredo, Margarita; Haz, Mar; García, Jorge; Quindós-Varela, María; Figueroa, Angélica; Antón-Aparicio, Luis M.; Calvo, Lourdes; Valladares-Ayerbes, Manuel (Future Science, 2014-06-20)
      [Abstract] Aim: To analyze GDF15 and MMP7 serum levels as diagnostic biomarkers in gastric cancer (GC) patients. The prognostic value of GDF15 and MMP7 serum levels in combination with miR-200c blood expression was also ...
    • Circulating microRNAs: molecular microsensors in gastrointestinal cancer 

      Blanco, Moisés; Calvo, Lourdes; Figueroa, Angélica; Haz, Mar; Antón-Aparicio, Luis M.; Valladares-Ayerbes, Manuel (MPDI, 2012-07-09)
      [Abstract] MicroRNAs (miRNAs) are small molecules of single strand non-coding RNAs, which are able to regulate gene expression. miRNAs have been involved in multiple cellular processes, such as proliferation, apoptosis and ...
    • Circulating miR-200c and miR-141 and outcomes in patients with breast cancer 

      Antolín, Silvia; Calvo, Lourdes; Blanco, Moisés; Paz Santiago, María; Lorenzo-Patiño, María J.; Haz, Mar; Santamarina, Isabel; Figueroa, Angélica; Antón-Aparicio, Luis M.; Valladares-Ayerbes, Manuel (BioMed Central, 2015)
      [Abstract] Background. The deregulation of microRNAs in both tumours and blood has led to the search for microRNAs to indicate the presence of cancer and predict prognosis. We hypothesize the deregulation of miR-200c/miR-141 ...
    • Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer 

      Valladares-Ayerbes, Manuel; Reboredo, Margarita; Medina Villaamil, Vanessa; Iglesias-Díaz, Pilar; Lorenzo-Patiño, María J.; Haz, Mar; Santamarina, Isabel; Blanco, Moisés; Fernández-Tajes, Juan; Quindós-Varela, María; Carral, Alberto; Figueroa, Angélica; Antón-Aparicio, Luis M.; Calvo, Lourdes (BioMed Central, 2012-09-06)
      [Abstract] Background. MicroRNAs are aberrantly expressed and correlate with tumourigenesis and the progression of solid tumours. The miR-200 family determines the epithelial phenotype of cancer cells and regulates ...
    • Clinical implications of epithelial cell plasticity in cancer progression 

      Antón-Aparicio, Luis M.; Blanco, Moisés; Castosa, Raquel; Concha, Ángel; Valladares-Ayerbes, Manuel; Calvo, Lourdes; Figueroa, Angélica (Elsevier, 2015)
      [Abstract] In the last few years, the role of epithelial cell plasticity in cancer biology research has gained increasing attention. This concept refers to the ability of the epithelial cells to dynamically switch between ...
    • Diagnostic accuracy of small breast epithelial mucin mRNA as a marker for bone marrow micrometastasis in breast cancer: a pilot study 

      Valladares-Ayerbes, Manuel; Iglesias-Díaz, Pilar; Díaz Prado, Silvia; Ayude, Daniel; Medina Villaamil, Vanessa; Haz, Mar; Reboredo, Margarita; Antolín, Silvia; Calvo, Lourdes; Antón-Aparicio, Luis M. (Springer-Verlag, 2009-02-17)
      [Abstract] Background. Detection of isolated tumour cells (ITC) in the blood or minimal deposits in distant organs such as bone marrow (BM) could be important to identify breast cancer patients at high risk of relapse or ...
    • Prognostic impact of disseminated tumor cells and microRNA-17-92 cluster deregulation in gastrointestinal cancer 

      Valladares-Ayerbes, Manuel; Blanco, Moisés; Haz, Mar; Medina, Vanessa; Iglesias-Díaz, Pilar; Lorenzo-Patiño, María J.; Reboredo, Margarita; Santamarina, Isabel; Figueroa, Angélica; Antón-Aparicio, Luis M.; Calvo, Lourdes (Spandidos, 2011-07-04)
      [Abstract] The presence of tumor cells in the bone marrow (BM) could be relevant to identifying high risk of disease progression and death in gastrointestinal cancer. However, the molecular profile associated with disseminated ...