Browsing by Author "Barreiro-Alonso, Aida"
Now showing items 1-15 of 15
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Aprendizaje cooperativo para el estudio semipresencial de técnicas de secuenciación de nueva generación
Barreiro-Alonso, Aida; Lamas, Mónica (Universidade da Coruña, Cufie, 2019)[Resumen] El aprendizaje cooperativo presenta un nuevo enfoque metodológico que pretende incrementar el rendimiento académico potenciando las relaciones sociales y el trabajo en grupo. En este trabajo, se ha diseñado el ... -
Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications
Barreiro-Alonso, Aida; Cámara-Quílez, María; Salamini-Montemurri, Martín; Lamas, Mónica; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Martínez-Iglesias, Olaia; Figueroa, Angélica; Cerdán, María Esperanza (MDPI, 2019-11-05)[Abstract] High mobility group box B (HMGB) proteins are pivotal in the development of cancer. Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement of HMGB proteins and their interactome ... -
Delineating the HMGB1 and HMGB2 Interactome in Prostate and Ovary Epithelial Cells and Its Relationship With Cancer
Barreiro-Alonso, Aida; Lamas, Mónica; García-Díaz, Rosa; Rodríguez-Belmonte, Esther; Yu, Lu; Pardo, Mercedes; Choudhary, Jyoti; Cerdán, María Esperanza (Impact Journals, 2018-04-10)[Abstract] High Mobility Group B (HMGB) proteins are involved in cancer progression and in cellular responses to platinum compounds used in the chemotherapy of prostate and ovary cancer. Here we use affinity purification ... -
Differential Characteristics of HMGB2 Versus HMGB1 and their Perspectives in Ovary and Prostate Cancer
Cámara-Quílez, M.; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza; Lamas, Mónica (Bentham Science, 2020)[Abstract] We have summarized common and differential functions of HMGB1 and HMGB2 proteins with reference to pathological processes, with a special focus on cancer. Currently, several “omic” approaches help us compare the ... -
HMG Proteins from Molecules to Disease [Editorial]
Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2022-02-17) -
HMGB1 Protein Interactions in Prostate and Ovary Cancer Models Reveal Links to RNA Processing and Ribosome Biogenesis through NuRD, THOC and Septin Complexes
Barreiro-Alonso, Aida; Lamas, Mónica; Lorenzo Catoira, Lidia; Pardo, Mercedes; Yu, Lu; Choudhary, Jyoti S.; Cerdán, María Esperanza (MDPI, 2021-09-18)[Abstract] This study reports the HMGB1 interactomes in prostate and ovary cancer cells lines. Affinity purification coupled to mass spectrometry confirmed that the HMGB1 nuclear interactome is involved in HMGB1 known ... -
Identification of lncRNAs Deregulated in Epithelial Ovarian Cancer Based on a Gene Expression Profiling Meta-Analysis
Salamini-Montemurri, Martín; Lamas, Mónica; Lorenzo-Catoira, Lidia; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2023-06-28)[Abstract] Epithelial ovarian cancer (EOC) is one of the deadliest gynecological cancers worldwide, mainly because of its initially asymptomatic nature and consequently late diagnosis. Long non-coding RNAs (lncRNA) are ... -
Interactome of Ixr1, HMGB1 and HMGB2 proteins in relation to their cellular functions
Barreiro-Alonso, Aida (2017)[Abstract]The Saccharomyces cerevisiae protein, Ixr1, and human HMGB1 and HMGB2 proteins belong to the HMGB protein family. The main objective of this work was to identify new proteins binding Ixr1, HMGB1 and HMGB2 ... -
O programa STEmbach na Área de Bioquímica e Bioloxía Molecular da Facultade de Ciencias
Lamas, Mónica; Lourido Salas, Lucía María; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Vizoso-Vázquez, Ángel (Centro Universitario de Formación e Innovación Educativa (CUFIE), Universidade da Coruña, 2022)[Resumo] O programa do bacharelato de excelencia en Ciencias e Tecnoloxía, STEMbach, é un programa da Xunta de Galicia, orientado a alumnos de primeiro e segundo de Bacharelato cuxo obxetivo é fomentar as ciencias entre ... -
Role of the E3 Ubiquitin-Ligase Hakai in Intestinal Inflammation and Cancer Bowel Disease
Roca-Lema, Daniel; Quiroga, Macarena; Khare, Vineeta; Díaz-Díaz, Andrea; Barreiro-Alonso, Aida; Rodríguez-Alonso, Andrea; Concha, Ángel; Romay, Gabriela; Cerdán, María Esperanza; Gasche, Christoph; Figueroa, Angélica (Springer Nature, 2022-10-20)[Abstract] The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the ... -
Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer [Review]
Lamas, Mónica; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Cámara-Quílez, M.; Cerdán, María Esperanza (MDPI, 2023-04-11)[Abstract] Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of ... -
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use
Salamini-Montemurri, Martín; Lamas, Mónica; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2020-04-21)[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor. In this review we aim to highlight ... -
The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer
Salamini-Montemurri, Martín; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Lorenzo-Catoira, Lidia; Rodríguez-Belmonte, Esther; Cerdán, María Esperanza; Lamas, Mónica (MDPI, 2024-03-07)[Abstract] Human high-mobility group-B (HMGB) proteins regulate gene expression in prostate cancer (PCa), a leading cause of oncological death in men. Their role in aggressive PCa cancers, which do not respond to hormonal ... -
The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis
Rico Díaz, Agustín; Barreiro-Alonso, Aida; Rey-Souto, Cora; Becerra, Manuel; Lamas, Mónica; Cerdán, María Esperanza; Vizoso-Vázquez, Ángel (MDPI, 2021-08-21)[Abstract] In the traditional fermentative model yeast Saccharomyces cerevisiae, ScIxr1 is an HMGB (High Mobility Group box B) protein that has been considered as an important regulator of gene transcription in response ... -
The HMGB1-2 Ovarian Cancer Interactome: the Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response
Cámara-Quílez, María; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2020-08-27)[Abstract] High mobility group box B (HMGB) proteins are overexpressed in different types of cancers such as epithelial ovarian cancers (EOC). We have determined the first interactome of HMGB1 and HMGB2 in epithelial ovarian ...
