Browsing by Author "Arenillas, Juan"
Now showing items 1-18 of 18
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A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment
Gallego-Fábrega, Cristina; Temprano-Sagrera, Gerard; Cárcel-Márquez, Jara; Muiño, Elena; Cullel, Natalia; Lledós, Miquel; Llucià-Carol, Laia; Martín-Campos, Jesús M.; Sobrino, Tomás; Castillo, José; Millán, Mónica; Muñoz-Narbona, Lucía; López-Cancio Martínez, Elena; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fàbregas, Joan; Freijo Guerrero, María del Mar; Moniche Álvarez, Francisco; Castellanos, María del Mar; Morrison, Alana C.; Smith, Nicholas L.; de Vries, Paul S.; Fernández-Cadenas, Israel; Sabater-Lleal, María (Elsevier, 2023-12-15)[Abstract] Background: Thrombolytic recombinant tissue plasminogen activator (r-tPA) treatment is the only pharmacologic intervention available in the ischemic stroke acute phase. This treatment is associated with an ... -
Delayed neurological improvement after full endovascular reperfusion in acute anterior circulation ischemic stroke
Talavera, Blanca; Gómez-Vicente, Beatriz; Martínez-Galdámez, Mario; López-Cancio, Elena; García-Cabo, Carmen; Castellanos, María del Mar; Roel, Alexia; Tejada-Meza, Herbert; Marta-Moreno, Javier; Pérez-Lázaro, Cristina; Navarro-Pérez, María Pilar; Bravo-Anguiano, Yolanda; Bártulos-Iglesias, Mónica; Tejada-García, Javier; Rodrigo-Stevens, Gabriela; Martínez-Zabaleta, Maite; Riva, Patricia de la; Timiraos-Fernández, Juan José; Freijo Guerrero, María del Mar; Luna, Alain; García-Sánchez, Juan Manuel; Gil-Alzueta, María del Carmen; Palacio-Portilla, Enrique Jesús; Jiménez-López, Yésica; López-Mesonero, Luis; Redondo-Robles, Laura; Mayo-Íscar, Agustín; Arenillas, Juan (American Heart Association, 2021-05-20)[Abstract] Background and purpose: We aimed to determine the prevalence and predictors of delayed neurological improvement (DNI) after complete endovascular reperfusion in anterior circulation acute ischemic stroke ... -
Dyslipidemias and stroke prevention: recommendations of the Study Group of Cerebrovascular Diseases of the Spanish Society of Neurology
Palacio-Portilla, Enrique Jesús; Roquer, Jaume; Amaro, Sergio; Arenillas, Juan; Ayo-Martín, Óscar; Castellanos, María del Mar; Freijo Guerrero, María del Mar; Fuentes, Blanca; García Pastor, Andrés; Gomis, Meritxell; Gómez Choco, Manuel; López-Cancio Martínez, Elena; Martínez Sánchez, Patricia; Morales, Ana; Rodríguez-Yáñez, Manuel; Segura, Tomás; Serena, Joaquín; Vivancos-Mora, José; Alonso de Ceciñana, María (Elsevier, 2022-01)[Abstract] Objective: We present an update of the Spanish Society of Neurology's recommendations for prevention of both primary and secondary stroke in patients with dyslipidaemia. Development: We performed a ... -
Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain
Tejada Meza, Herbert; Lambea Gil, Álvaro; Sancho Saldaña, Agustín; Martínez-Zabaleta, Maite; Riva Juez, Patricia de la; López-Cancio Martínez, Elena; Castañón Apilánez, María; Herrera Isasi, María; Marta Enguita, Juan; Lera Alfonso, Mercedes de; Arenillas, Juan; Segurola Olaizola, Jon; Timiraos Fernández, Juan José; Sánchez, Joaquín; Castellanos, María del Mar; Roel, Alexia; Casado Menéndez, Ignacio; Freijo Guerrero, María del Mar; Luna Rodríguez, Alain; Palacio Portilla, Enrique; Jiménez López, Yésica; Rodríguez Castro, Emilio; Arias Rivas, Susana; Tejada García, Javier; Beltrán Rodríguez, Iria; Julián-Villaverde, Francisco; Moreno García, María Pilar; Trejo-Gabriel-Galán, José María; Echevarría Íñiguez, Ana; Tejero Juste, Carlos; Pérez Lázaro, Cristina; Marta Moreno, Javier (Sage, 2020-06-11)[Abstract] Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital ... -
Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain
Tejada Meza, Herbert; Lambea Gil, Álvaro; Sancho Saldaña, Agustín; Martínez-Zabaleta, Maite; de la Riva, Patricia; López-Cancio Martínez, Elena; Castañón Apilánez, María; Herrera Isasi, María; Marta Enguita, Juan; Lera Alfonso, Mercedes de; Arenillas, Juan; Segurola Olaizaola, Jon; Timiraos Fernández, Juan José; Sánchez, Joaquín; Castellanos, María del Mar; Roel, Alexia; Casado Menéndez, Ignacio; Freijo Guerrero, María del Mar; Luna, Alain; Palacio-Portilla, Enrique Jesús; Jiménez López, Yésica; Rodríguez Castro, Emilio; Arias Rivas, Susana; Tejada García, Javier; Beltrán Rodríguez, Iria; Julián Villaverde, Francisco; Moreno García, María Pilar; Trejo-Gabriel-Galán, José María; Echevarría Íñiguez, Ana; Tejero Juste, Carlos; Pérez Lázaro, Cristina; Marta Moreno, Javier (Sage, 2020-06-11)[Abstract] Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital ... -
Impact of mediterranean diet prior to stroke on the prognosis of patients undergoing endovascular treatment
García-Cabo, Carmen; Castañón Apilánez, María; Benavente-Fernández, Lorena; Jiménez, José María; Arenillas, Juan; Castellanos, María del Mar; Rodrigo-Stevens, Gabriela; Tejada Meza, Herbert; Pérez, Cristina; Martínez-Zabaleta, Maite; Rodríguez-Castro, Emilio; Sánchez, Joaquín; Julián-Villaverde, Francisco; Pinedo Brochado, Ana; Palacio, Enrique; López-Cancio Martínez, Elena (Karger, 2021-03-17)[Abstract] Introduction: Mediterranean diet (MeDiet) has been associated with lower risk of stroke. Additionally, animal models suggested that some components of MeDiet are associated with better outcomes after ischemic ... -
Incidence and outcoMes of MInor stroke and high-risk traNsient ischEmic attack in NordicTus: IMMINENT study
Ramos-Araque, María E.; Castellanos, María del Mar; Naya Rios, Lucía; López-Cancio Martínez, Elena; Molina-Gil, Javier; Marta Moreno, Javier; Tejada Meza, Herbert; Temprano-Fernández, María Teresa; Antón-González, Celia; Vidal-de Francisco, Diana; Tejada García, Javier; Maciñeiras Montero, José Luis; Vicente Alba, Pablo; García-Sánchez, Juan Manuel; Aguilera-Irazabal, Borja; Martínez-Zabaleta, Maite; Díez, I.N.; Pinedo Brochado, Ana; Azcune-Calle, Itxaso; Freijo Guerrero, María del Mar; Moreno-Estebanez, A.; Palacio-Portilla, Enrique Jesús; Manrique Arregui, L.; Rodríguez-Yáñez, Manuel; Santamaría Cadavid, María; Timiraos Fernández, Juan José; Herrero-Infante, Yolanda; Trejo-Gabriel-Galán, José María; Echavarría-Iñiguez, Ana; Tejero Juste, Carlos; Rodríguez-Montolio, Joana; Julián Villaverde, Francisco José; Moreno García, María Pilar; López-Mesonero, Luis; Redondo-Robles, Laura; Aymerich, Nuria; Korroza, J.; Arenillas, Juan (Elsevier, 2024-07-03)[Abstract] Background. Our primary aim was to investigate the incidence of non-cardioembolic minor acute ischemic stroke (AIS) and high-risk transient ischemic attack (TIA) and to identify predictors of stroke recurrence/death ... -
Oral anticoagulation and risk of symptomatic hemorrhagic transformation in stroke patients treated with mechanical thrombectomy: data from the nordictus registry
Ramos-Araque, María E.; Chavarría-Miranda, Alba; Gómez-Vicente, Beatriz; López-Cancio Martínez, Elena; Castañón Apilánez, María; Castellanos, María del Mar; López Fernández, María; Tejada Meza, Herbert; Marta Moreno, Javier; Tejada García, Javier; Beltrán Rodríguez, Iria; de la Riva, Patricia; Díez, Noemí; Arias Rivas, Susana; Santamaría Cadavid, María; Bravo Anguiano, Yolanda; Bártulos Iglesias, Mónica; Palacio-Portilla, Enrique Jesús; Revilla García, Marian; Timiraos Fernández, Juan José; Arenaza Basterrechea, Naroa; Maciñeiras Montero, José Luis; Vicente Alba, Pablo; Julián Villaverde, Francisco José; Pinedo Brochado, Ana; Azkune, Itxaso; Freijo Guerrero, María del Mar; Luna, Alain; Arenillas, Juan (Frontiers, 2020-11-26)[Abstract] Introduction: We aimed to evaluate if prior oral anticoagulation (OAC) and its type determines a greater risk of symptomatic hemorrhagic transformation in patients with acute ischemic stroke (AIS) subjected to ... -
Prevención de ictus en pacientes con diabetes mellitus tipo 2 o prediabetes: recomendaciones del Grupo de Estudio de Enfermedades Cerebrovasculares de la Sociedad Española de Neurología
Fuentes, Blanca; Amaro, Sergio; Alonso de Ceciñana, María; Arenillas, Juan; Ayo-Martín, Óscar; Castellanos, María del Mar; Freijo Guerrero, María del Mar; García Pastor, Andrés; Gomis, Meritxell; Gómez Choco, Manuel; López-Cancio Martínez, Elena; Martínez Sánchez, Patricia; Morales, Ana; Palacio-Portilla, Enrique Jesús; Rodríguez-Yáñez, Manuel; Roquer, Jaume; Segura, Tomás; Serena, Joaquín; Vivancos-Mora, José (Elsevier, 2020-09-24)[Resumen] Objetivo. Actualizar las recomendaciones de la Sociedad Española de Neurología para la prevención del ictus en pacientes con DM-2 o prediabetes, analizando las evidencias disponibles sobre el efecto del control ... -
Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: consensus document and practice guidance
Gil-Núñez, Antonio; Masjuan, Jaime; Montaner, Joan; Castellanos, María del Mar; Segura, Tomás; Cardona, Pere; Tembl, José Ignacio; Purroy, Francesc; Arenillas, Juan; Palacio, Enrique (Elsevier, 2021-12-11)[Abstract] Introduction: Patients with history of stroke or transient ischaemic attack present considerable risk of future vascular events. Reducing levels of low-density lipoprotein (LDL) cholesterol decreases the ... -
Recommendations of the Spanish Society of Neurology for the prevention of stroke: interventions on lifestyle and air pollution
García Pastor, Andrés; López-Cancio Martínez, Elena; Rodríguez-Yáñez, Manuel; Alonso de Ceciñana, María; Amaro, Sergio; Arenillas, Juan; Ayo-Martín, Óscar; Castellanos, María del Mar; Fuentes, Blanca; Freijo Guerrero, María del Mar; Gomis, Meritxell; Gómez Choco, Manuel; Martínez Sánchez, Patricia; Morales, Ana; Palacio-Portilla, Enrique Jesús; Segura, Tomás; Serena, Joaquín; Vivancos-Mora, José; Roquer, Jaume (Elsevier, 2021-03-27)[Abstract] Objective: To update the recommendations of the Spanish Society of Neurology regarding lifestyle interventions for stroke prevention. Development: We reviewed the most recent studies related to lifestyle ... -
RP11-362K2.2:RP11-767I20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma: a GWAS meta-analysis
Muiño, Elena; Cárcel-Márquez, Jara; Carrera, Caty; Llucià-Carol, Laia; Gallego-Fábrega, Cristina; Cullel, Natalia; Lledós, Miquel; Castillo, José; Sobrino, Tomás; Campos, Francisco; Rodríguez-Castro, Emilio; Millán, Mónica; Muñoz-Narbona, Lucía; Bustamante, Alejandro; López-Cancio Martínez, Elena; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Giralt-Steinhauer, Eva; Soriano-Tárraga, Carolina; Vives-Bauza, Cristófol; Díaz Navarro, Rosa; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fàbregas, Joan; Delgado-Mederos, Raquel; Camps-Renom, Pol; Prats-Sánchez, Luis; Guisado, Daniel; Guasch, Marina; Marin, Rebeca; Martínez-Domeño, Alejandro; Freijo Guerrero, María del Mar; Moniche Álvarez, Francisco; Cabezas, Juan Antonio; Castellanos, María del Mar; Krupinsky, Jerzy; Strbian, Daniel; Tatlisumak, Turgut; Thijs, Vincent; Lemmens, Robin; Slowik, Agnieszka; Pera, Joanna; Heitsch, Laura; Ibáñez, Laura; Cruchaga, Carlos; Dhar, Rajat; Lee, Jin-Moo; Montaner, Joan; Fernández-Cadenas, Israel (MDPI, 2021-07-16)[Abstract] Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase ... -
Safety and efficacy of ApTOLL in patients with ischemic stroke undergoing endovascular treatment: a phase 1/2 randomized clinical trial
Hernández-Jiménez, Macarena; Abad-Santos, Francisco; Cotgreave, Ian; Gallego, Jaime; Jilma, Bernd; Flores, Alan; Jovin, Tudor G.; Vivancos, José; Hernández-Pérez, María; Molina, Carlos A.; Montaner, Joan; Casariego, Joaquín; Dalsgaard, Mads; Liebeskind, David S.; Cobo, Erik; Castellanos, María del Mar; Cardona Portela, Pere; Masjuán, Jaime; Moniche, Francisco; Tembl, José Ignacio; Terceño Izaga, Mikel; Arenillas, Juan; Calleja, Patricia; Olivot, Jean Marc; Calviere, Lionel; Henon, Hilde; Mazighi, Mikael; Piñeiro, David; Pugliese, Marco; González, Víctor M.; Moro, María Ángeles; García-Tornel, Álvaro; Lizasoain, Ignacio; Ribo, Marc (American Medical Association, 2023-06-20)[Abstract] Importance: ApTOLL is a TLR4 antagonist with proven preclinical neuroprotective effect and a safe profile in healthy volunteers. Objective: To assess the safety and efficacy of ApTOLL in combination with ... -
Serum cellular fibronectin and matrix metalloproteinase-9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke: a multicenter confirmatory study
Castellanos, María del Mar; Sobrino, Tomás; Millán, Mónica; García, María M.; Arenillas, Juan; Nombela, Florentino; Brea, David; Pérez de la Ossa, Natalia; Serena, Joaquín; Vivancos, José; Castillo, José; Dávalos, Antoni (American Heart Association, 2007-05-03)[Abstract] Background and purpose: Plasma levels of cellular fibronectin (c-Fn) > or =3.6 microg/mL and of matrix metalloproteinase-9 (MMP-9) > or =140 ng/mL have been associated with parenchymal hematoma (PH) after ... -
Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma
Carrera, Caty; Cárcel-Márquez, Jara; Cullel, Natalia; Torres-Águila, Nuria; Muiño, Elena; Castillo, José; Sobrino, Tomás; Campos, Francisco; Rodríguez-Castro, Emilio; Llucià-Carol, Laia; Millán, Mónica; Muñoz-Narbona, Lucía; López-Cancio, Elena; Bustamante, Alejandro; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Giralt-Steinhauer, Eva; Soriano-Tárraga, Carolina; Mola-Caminal, Marina; Vives-Bauza, Cristófol; Díaz Navarro, Rosa; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fábregas, Joan; Delgado-Mederos, Raquel; Freijo Guerrero, María del Mar; Moniche, Francisco; Cabezas, Juan Antonio; Castellanos, María del Mar; Gallego-Fábrega, Cristina; González-Sánchez, Jonathan; Krupinsky, Jurek; Strbian, Daniel; Tatlisumak, Turgut; Thijs, Vincent; Lemmens, Robin; Slowik, Agnieszka; Pera, Johanna; Kittner, Steven; Cole, John; Heitsch, Laura; Ibáñez, Laura; Cruchaga, Carlos; Lee, Jin-Moo; Montaner, Joan; Fernández-Cárdenas, Israel (Oxford University Press, 2021-03-16)[Abstract] Haemorrhagic transformation is a complication of recombinant tissue-plasminogen activator treatment. The most severe form, parenchymal haematoma, can result in neurological deterioration, disability, and death. ... -
Stroke prevention in patients with arterial hypertension: recommendations of the Spanish Society of Neurology's Stroke Study Group
Rodríguez-Yáñez, Manuel; Gómez Choco, Manuel; López-Cancio Martínez, Elena; Amaro, Sergio; Alonso de Ceciñana, María; Arenillas, Juan; Ayo-Martín, Óscar; Castellanos, María del Mar; Freijo Guerrero, María del Mar; García Pastor, Andrés; Gomis, Meritxell; Martínez Sánchez, Patricia; Morales, Ana; Palacio-Portilla, Enrique Jesús; Roquer, Jaume; Segura, Tomás; Serena, Joaquín; Vivancos-Mora, José; Fuentes, Blanca (Elsevier, 2021-04-23)[Abstract] Objective: To update the recommendations of the Spanish Society of Neurology on primary and secondary stroke prevention in patients with arterial hypertension. Development: We proposed several questions ... -
Use of cardiovascular polypills for the secondary prevention of cerebrovascular disease
Masjuan, Jaime; Gállego, Jaime; Aguilera, José María; Arenillas, Juan; Castellanos, María del Mar; Díaz, Fernando; Portilla, Juan Carlos; Purroy, Francesc (Elsevier, 2019-08-11)[Abstract] Introduction: There is little control of cardiovascular (CV) risk factors in secondary prevention after an ischaemic stroke, in part due to a lack of adherence to treatment. The CV polypill may contribute ... -
Will neurological care change over the next 5 years due to the COVID-19 pandemic?: key informant consensus survey
Matías-Guiu, J.; Matías-Guiu, Jordi A.; Álvarez-Sabín, José; Ara, José Ramón; Arenillas, Juan; Casado-Naranjo, Ignacio; Castellanos, María del Mar; Jiménez-Hernández, María Dolores; Lainez-Andrés, José Miguel; Moral, Esther; Morales, Ana; Rodríguez-Antigüedad, Alfredo; Segura, Tomás; Serrano-Castro, Pedro; Díez-Tejedor, Exuperio (Elsevier, 2020-05-21)[Abstract] Introduction. The COVID-19 pandemic will give rise to long-term changes in neurological care, which are not easily predictable. Material and methods. A key informant survey was used to enquire about the changes ...