Listar por tema "Sunitinib"

Mostrando ítems 1-3 de 3

    • Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma 

      Puente, Javier; Lainez, Nuria; Dueñas, Marta; Méndez-Vidal, María José; Esteban, Emilio; Castellano, Daniel; Martínez-Fernández, Mónica; Basterretxea, Laura; Juan-Fita, María José; Antón-Aparicio, Luis M.; León, Luis; Lambea, Julio; Pérez-Valderrama, Begoña; Vázquez, Sergio; Suárez, Cristina; García del Muro, Xavier; Gallardo, Enrique; Maroto, José Pablo; Samaniego, M. Luz; Suárez-Paniagua, Beatriz; Sanz, Julián; Paramio, Jesús M. (Impact Journals, 2017-03-23)
      [Abstract] Background: Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further ...

    • Sunitinib-induced asthenia: from molecular basis to clinical relief 

      Antón-Aparicio, Luis M.; Grande Pulido, Enrique; Aparicio Gallego, Guadalupe (Taylor & Francis, 2011-11-01)
      [Abstract] Asthenia-fatigue syndrome (AFS) is defined as a persistent, subjective sense of tiredness related to cancer or its treatment and greatly impacts quality of life among cancer patients. All tyrosine kinase inhibitors, ...

    • Treatment of sunitinib-induced hypertension in solid tumor by nitric oxide donors 

      León-Mateos, L.; Mosquera, J.; Antón-Aparicio, Luis M. (Elsevier, 2015-09-10)
      [Abstract] Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) are overexpressed in the majority of renal cell carcinomas. This characteristic has supported the rationale of targeting VEGF-driven tumour ...